Calcitriol + Eicosapentaenoic Acid Softgel Capsule: Comprehensive Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe nausea, vomiting, or abdominal pain
- Confusion, drowsiness, or irregular heartbeat
- Excessive thirst and frequent urination
- Blood in urine or severe flank pain
- Swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is calzomix max soft gelatin capsule used for?
This medicine is a combination of Calcitriol and Eicosapentaenoic Acid used to support bone health and reduce inflammation. It is taken orally once daily with food.
- Generic Name: Calcitriol + Eicosapentaenoic Acid
- Manufacturer: Venova Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 calzomix max soft gelatin capsule के बारे में (Hindi Summary)
उपयोग: यह दवा कैल्सिट्रियोल और ईकोसापेंटेनोइक एसिड का संयोजन है, जिसका उपयोग हड्डियों की मजबूती के लिए और सूजन कम करने के लिए किया जाता है। यह ऑस्टियोपोरोसिस, क्रोनिक किडनी रोग और कैल्शियम की कमी में मदद करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, कब्ज, सिरदर्द और धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन उच्च कैल्शियम स्तर, गुर्दे की पथरी या एलर्जी प्रतिक्रिया हो सकती है।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। कैल्शियम और किडनी फंक्शन की नियमित जांच कराएं। बिना सलाह के अन्य विटामिन डी या कैल्शियम सप्लीमेंट न लें। पर्याप्त पानी पिएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 calzomix max soft gelatin capsule Uses & Benefits
[{"condition":"Osteoporosis","description":"Helps maintain bone density and reduces fracture risk by improving calcium absorption.","evidence":"Well-established"},{"condition":"Chronic kidney disease-associated mineral bone disorder","description":"Used to manage low calcium levels and bone disease in patients with kidney disease.","evidence":"Well-established"},{"condition":"Hypocalcemia","description":"Treats low blood calcium levels, especially in patients with hypoparathyroidism.","evidence":"Well-established"},{"condition":"Inflammatory conditions","description":"Eicosapentaenoic Acid may help reduce inflammation in conditions like rheumatoid arthritis.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Cardiovascular risk reduction","description":"Omega-3 fatty acids may be used off-label to support heart health.","evidence":"Limited"},{"condition":"Depression","description":"Some evidence suggests omega-3s may help with mood disorders, but not standard.","evidence":"Limited"}]
Primary treatment for: Osteoporosis
Also treats: Chronic kidney disease, Hypocalcemia, Rheumatoid arthritis
📋 Drug Information
| Generic Name(s) | Calcitriol + Eicosapentaenoic Acid |
| Brand Name | Calcigo Max Softgel Capsule |
| Manufacturer | Venova Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Vitamin D Analog + Omega-3 Fatty Acid |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Calcitriol binds to vitamin D receptors in the intestine, bone, kidney, and parathyroid glands, increasing calcium absorption and regulating bone mineralization. Eicosapentaenoic Acid is incorporated into cell membranes and competes with arachidonic acid for cyclooxygenase and lipoxygenase enzymes, reducing the production of pro-inflammatory eicosanoids.
Mechanism Steps
💡 How to Take calzomix max soft gelatin capsule
Strength: Each softgel capsule contains Calcitriol 0.25 mcg and Eicosapentaenoic Acid 180 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one softgel capsule once daily or as directed by your physician. The dose may be adjusted based on your calcium levels, kidney function, and the condition being treated. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of calcitriol. Dose adjustment may be necessary based on renal function and calcium levels. Consult your doctor. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be required. Monitor calcium and phosphate levels closely. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Monitor liver function and calcium levels. |
| Maximum Daily Dose | The maximum daily dose should not exceed one capsule unless prescribed otherwise by your doctor. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of calzomix max soft gelatin capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Thiazide diuretics | Major | |
| Digoxin | Major | |
| Warfarin | Major | |
| Corticosteroids | Moderate | |
| Orlistat | Moderate | |
| Bile acid sequestrants | Moderate | |
| Antacids (magnesium) | Minor | |
| Ketoconazole | Minor |
🚨 Major Interactions
- Thiazide diuretics
- Digoxin
- Warfarin
⚡ Moderate Interactions
- Corticosteroids
- Orlistat
- Bile acid sequestrants
🍷 Alcohol Interaction
Alcohol may impair calcium absorption and increase risk of bone loss. It is advisable to limit or avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypercalcemia","Hypervitaminosis D","Hypersensitivity to calcitriol, eicosapentaenoic acid, or any component","Severe renal impairment without monitoring","Hyperphosphatemia"]
⚠️ Warnings & Precautions
["Monitor calcium levels regularly to avoid hypercalcemia.","Avoid concurrent use of other vitamin D supplements without medical advice.","Use cautiously in patients with kidney stones or renal impairment.","May increase risk of bleeding when taken with anticoagulants.","Not recommended for children without pediatrician guidance.","Inform your doctor if you are pregnant or breastfeeding."]
🤱 Lactation Safety
Calcitriol is excreted in breast milk. Eicosapentaenoic Acid is also present in breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause hypercalcemia, nausea, vomiting, confusion, and cardiac arrhythmias. Seek immediate medical attention. Treatment includes discontinuation of the medicine, hydration, and symptomatic management. In severe cases, corticosteroids or calcitonin may be used.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Regular blood tests to monitor calcium, phosphate, and kidney function are important. Avoid taking additional vitamin D or calcium supplements without consulting your doctor. Stay well hydrated. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Avoid alcohol as it may affect calcium metabolism. Do not stop this medicine abruptly without medical advice. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to hypercalcemia and kidney issues. Regular monitoring and dose adjustments are important.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy. Calcitriol may be continued if benefits outweigh risks, but dose adjustment may be needed.
🏥 Post-Surgery Considerations
Inform your surgeon about this medicine before any surgery. It may affect calcium levels and bleeding risk.
🦷 Dental Procedures
Inform your dentist about this medicine, especially if you have a history of bleeding or are on anticoagulants.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is encouraged, but avoid high-impact activities if you have osteoporosis or joint pain. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine generally does not affect your ability to work or drive. However, if you experience dizziness or confusion due to high calcium, avoid driving or operating machinery.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use requires regular monitoring of calcium, phosphate, and kidney function. Unmonitored use can lead to hypercalcemia, kidney stones, and soft tissue calcification. Periodic dose adjustments may be needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May be used alone if EPA is not needed.
Evidence: Well-establishedIncreasing calcium and omega-3 intake through food.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. Continue routine vaccinations as advised by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme heat. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Calcitriol starts working within hours, but improvements in bone health may take weeks to months.
A: Consult your doctor before adding any supplements, especially calcium or vitamin D.
🤔 Common Patient Concerns
🔄 Substitutes for calzomix max soft gelatin capsule
View AllAlternative brands with exact same active ingredient:
-
biocod-mx softgel capsuleWinsome Bioceuticals ₹365.60 14.3% COSTLIER
-
calcigo max softgel capsuleResolute Healthcare ₹392.80 22.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. - Myth: More is better for bone health.
Fact: Taking more than prescribed can lead to dangerous high calcium levels.
🔄 Alternative Options
Generic Alternatives
- Calcitriol + Eicosapentaenoic Acid softgel capsules