calzomix max soft gelatin capsule - Calcitriol (0.25mcg) + Eicosapentaenoic Acid (180mg) medicine

calzomix max soft gelatin capsule

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๐Ÿญ Venova Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jul 4, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 04, 2026

What is calzomix max soft gelatin capsule used for?

Calcigo Max Softgel Capsule (Calcitriol + Eicosapentaenoic Acid) is used to treat VITAMINS MINERALS NUTRIENTS. It contains Calcitriol (0.25mcg) + Eicosapentaenoic Acid (180mg), which Calcitriol binds to vitamin D receptor (VDR) to regulate calcium and phosphate h. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Calcitriol + Eicosapentaenoic Acid
  • Manufacturer: Venova Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š calzomix max soft gelatin capsule Uses & Benefits

Osteoporosis, vitamin D deficiency, hyperparathyroidism, dyslipidemia, cardiovascular support.

Off-label uses: Psoriasis, autoimmune conditions, cognitive decline.

๐Ÿ“‹ Drug Information

Generic Name(s)Calcitriol + Eicosapentaenoic Acid
Brand NameCalcigo Max Softgel Capsule
ManufacturerVenova Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action ClassVitamin D Analog + Omega-3 Fatty Acid
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionCalcitriol is rapidly absorbed from the gastrointestinal tract; EPA is well absorbed in the small intestine.
DistributionCalcitriol is distributed to bones, kidneys, and other tissues; EPA is incorporated into cell membranes.
Protein BindingCalcitriol: ~99.9% bound to vitamin D-binding protein; EPA: highly bound to albumin.
MetabolismCalcitriol is metabolized in the kidney and liver; EPA undergoes beta-oxidation and elongation.
Half-LifeCalcitriol: 5-7 hours; EPA: approximately 7-10 days.
ExcretionCalcitriol: primarily excreted in bile and feces; EPA: exhaled as CO2 and excreted in urine.
BioavailabilityCalcitriol: ~70%; EPA: ~90%.
Onset of ActionCalcitriol: 2-6 hours; EPA: weeks to months.
Peak Plasma TimeCalcitriol: 3-6 hours; EPA: 5-7 hours.
Duration of ActionCalcitriol: 3-5 days; EPA: sustained with regular dosing.

How It Works

Calcitriol binds to vitamin D receptor (VDR) to regulate calcium and phosphate homeostasis; EPA reduces inflammation and modulates lipid metabolism.

Mechanism Steps

1Calcitriol binds to VDR in intestinal cells, increasing calcium absorption.
2Calcitriol stimulates osteoclast activity, releasing calcium from bone.
3Calcitriol enhances renal calcium reabsorption.

๐Ÿ’ก How to Take calzomix max soft gelatin capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of calzomix max soft gelatin capsule

โœ… Common Side Effects

  • Hypercalcemia
  • Nausea
  • Constipation
  • Metallic taste
  • Fishy burps

๐Ÿšจ Serious Side Effects

  • Arrhythmias
  • Kidney stones
  • Pancreatitis
  • Allergic reactions

โš ๏ธ Rare Side Effects

  • Pseudotumor cerebri
  • Hepatic steatosis
  • Bleeding tendencies

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Thiazide diuretics Major Increased risk of hypercalcemia
Digitalis glycosides Major Increased risk of arrhythmias due to hypercalcemia
Cholestyramine Major Reduced absorption of calcitriol
Orlistat Major Reduced absorption of EPA
Corticosteroids Moderate Reduced calcium absorption
Phenytoin Moderate Increased metabolism of calcitriol
Barbiturates Moderate Increased metabolism of calcitriol
Rifampin Moderate Increased metabolism of calcitriol
Magnesium-containing antacids Minor Possible hypermagnesemia
Calcium supplements Minor Increased risk of hypercalcemia

๐Ÿšจ Major Interactions

  • Thiazide diuretics
  • Digitalis glycosides
  • Cholestyramine
  • Orlistat

โšก Moderate Interactions

  • Corticosteroids
  • Phenytoin
  • Barbiturates
  • Rifampin

โ„น๏ธ Minor Interactions

  • Magnesium-containing antacids
  • Calcium supplements

๐Ÿฝ๏ธ Food Interactions

Avoid excessive intake of calcium-rich foods; EPA absorption enhanced with fatty meals.

๐Ÿท Alcohol Interaction

Alcohol may reduce EPA levels and increase risk of liver toxicity.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypercalcemia, hypervitaminosis D, known hypersensitivity, severe renal impairment.

๐Ÿ“Š Monitoring Parameters

Serum calcium, phosphate, vitamin D levels, renal function, lipid profile.

๐Ÿคฑ Lactation Safety

Calcitriol is excreted in breast milk; EPA is present in breast milk; caution advised.

๐Ÿ’Š Overdose Management

Discontinue medication, monitor serum calcium, supportive care, hydration, loop diuretics if needed.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Jul 04, 2026

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