Calmer 10mg Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Irregular or fast heartbeat
- Fainting or loss of consciousness
- Seizures or convulsions
- Severe allergic reaction (rash, swelling, difficulty breathing)
- Yellowing of skin or eyes (jaundice)
- Unusual bruising or bleeding
- Severe drowsiness or confusion
If experiencing severe symptoms, call emergency services immediately.
What is calmer 10mg syrup used for?
This medicine is an oral syrup containing hydroxyzine, an antihistamine used to treat allergic conditions like hay fever and hives, as well as anxiety and preoperative sedation. It works by blocking histamine receptors and has a calming effect. It is available by prescription only.
- Generic Name: Hydroxyzine
- Manufacturer: Esquire Drug House
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 calmer 10mg syrup के बारे में (Hindi Summary)
उपयोग: यह दवा हाइड्रोक्सीज़िन नामक एंटीहिस्टामिन का सिरप रूप है, जिसका उपयोग एलर्जी जैसे नाक बहना, छींक आना, खुजली, पित्ती और त्वचा पर लाल चकत्ते के इलाज के लिए किया जाता है। यह चिंता और घबराहट को कम करने और सर्जरी से पहले मरीज को शांत करने के लिए भी इस्तेमाल किया जाता है। यह दवा दिमाग में हिस्टामिन रिसेप्टर्स को ब्लॉक करके काम करती है, जिससे एलर्जी के लक्षण कम होते हैं और नींद आती है। यह केवल डॉक्टर के पर्चे पर मिलती है और डॉक्टर की सलाह के अनुसार ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सबसे आम दुष्प्रभावों में नींद आना, मुँह सूखना, सिरदर्द, चक्कर आना और धुंधली दृष्टि शामिल हैं। कुछ लोगों को कब्ज या जी मिचलाना भी हो सकता है। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको दिल की धड़कन तेज या अनियमित लगे, दौरा पड़े, या गंभीर एलर्जी हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा न बढ़ाएँ। इस दवा को लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या कोई अन्य दवा ले रही हैं, तो डॉक्टर को बताएं। दवा को बच्चों की पहुँच से दूर, ठंडी और सूखी जगह पर रखें।
💊 calmer 10mg syrup Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, and itchy, watery eyes caused by seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Urticaria (hives)","description":"Reduces itching and the size of hives by blocking histamine release.","evidence":"Well-established"},{"condition":"Anxiety","description":"Provides short-term relief of anxiety symptoms due to its sedative properties.","evidence":"Well-established"},{"condition":"Preoperative sedation","description":"Used to calm patients before surgery and reduce anxiety.","evidence":"Well-established"},{"condition":"Pruritus (itching) due to various causes","description":"Helps control itching associated with skin conditions or allergies.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Insomnia","description":"Sometimes used off-label as a short-term sleep aid due to its sedative effects.","evidence":"Limited"},{"condition":"Nausea and vomiting","description":"Occasionally used for its antiemetic properties, though not a first-line choice.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Urticaria, Anxiety, Pruritus, Preoperative sedation
📋 Drug Information
| Generic Name(s) | Hydroxyzine |
| Brand Name | Atarax |
| Manufacturer | Esquire Drug House |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | H1 Antihistaminics (First Generation) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the bottle tightly closed when not in use. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively blocking histamine H1 receptors in the central nervous system and peripheral tissues. By occupying these receptors, it prevents histamine from binding and triggering allergic responses such as itching, sneezing, and vasodilation. Additionally, it has anticholinergic and central nervous system depressant effects, which contribute to its sedative and anti-anxiety actions.
Mechanism Steps
💡 How to Take calmer 10mg syrup
Strength: Each 5 ml of syrup contains 10 mg of hydroxyzine.
Dosage Information
| Adult Dosage | The usual adult dose for anxiety is 25 to 100 mg three to four times daily. For allergic conditions, the dose is 25 to 50 mg three to four times daily. For preoperative sedation, 50 to 100 mg is given 30 to 60 minutes before surgery. The syrup formulation allows for flexible dosing. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | For children over 2 years of age, the dose is based on weight and is typically 0.5 to 1 mg/kg per dose, given every 6 to 8 hours as needed. The maximum dose should not exceed 100 mg per day. Pediatric dosing is not established from available information for children under 2 years. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. The starting dose should be reduced, typically 25 mg once or twice daily, and increased cautiously based on response and tolerability. Regular monitoring for confusion, falls, and urinary retention is advised. |
| Renal Impairment | In patients with renal impairment, the dose should be reduced due to decreased clearance. The exact adjustment depends on the degree of impairment. Consult a healthcare professional for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, the dose should be reduced because hydroxyzine is metabolized in the liver. The exact adjustment depends on the severity of impairment. Consult a healthcare professional for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose for adults is 400 mg per day in divided doses. For children, the maximum daily dose is 100 mg per day. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of calmer 10mg syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| CNS depressants | Major | |
| MAO inhibitors | Major | |
| QT-prolonging drugs | Major | |
| Anticholinergic drugs | Moderate | |
| Beta-blockers | Moderate | |
| Cimetidine | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- CNS depressants (e.g., opioids, benzodiazepines, alcohol)
- MAO inhibitors
- QT-prolonging drugs (e.g., amiodarone, sotalol, certain antipsychotics)
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, benztropine, tricyclic antidepressants)
- Beta-blockers
- Cimetidine
🍷 Alcohol Interaction
Alcohol should be strictly avoided while taking this medicine because it can significantly enhance the sedative and central nervous system depressant effects, leading to excessive drowsiness, impaired coordination, and increased risk of accidents.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to hydroxyzine or any component of the formulation","Use in patients with prolonged QT interval or congenital long QT syndrome","Severe hepatic impairment","Narrow-angle glaucoma","Urinary retention","Use in early pregnancy (first trimester) unless clearly needed"]
⚠️ Warnings & Precautions
["May impair mental and physical abilities required for driving or operating machinery.","Avoid concurrent use with alcohol or other CNS depressants.","Use with caution in elderly patients due to increased risk of confusion, falls, and anticholinergic effects.","May cause anticholinergic effects; use with caution in patients with glaucoma, constipation, or urinary retention.","Prolonged use may lead to tolerance and dependence.","Do not use in children under 2 years of age unless directed by a doctor.","May cause false-positive results in certain urine steroid tests."]
🤱 Lactation Safety
Hydroxyzine is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose of this medicine may cause severe drowsiness, confusion, seizures, respiratory depression, and cardiac arrhythmias. If overdose is suspected, seek emergency medical attention immediately. Treatment is supportive and symptomatic, including gastric lavage if within 1-2 hours of ingestion, monitoring of vital signs, and management of seizures or arrhythmias. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it more often than directed. Avoid driving or operating machinery until you know how this medicine affects you, as it can cause significant drowsiness. Do not drink alcohol while taking this medicine, as it can intensify drowsiness and impair your ability to think clearly. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Also tell your doctor about all other medicines you are taking, especially those for depression, anxiety, or sleep, as well as any heart rhythm medicines. Keep this medicine out of reach of children and store it at room temperature away from direct sunlight. Do not use it after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to the sedative and anticholinergic effects of this medicine, including confusion, dry mouth, constipation, and urinary retention. They are also at higher risk of falls. The starting dose should be lower, and regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. It is classified as Pregnancy Category C, and its safety in pregnancy is not fully established. Alternative treatments may be considered.
🏥 Post-Surgery Considerations
This medicine may be used for preoperative sedation. After surgery, it may add to the effects of anesthesia and other medications, increasing drowsiness and respiratory depression. Inform your surgeon and anesthesiologist if you are taking this medicine.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it can cause dry mouth and may interact with other medications used during dental procedures. It may also increase drowsiness when combined with sedatives used in dentistry.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness, which may affect your coordination and balance. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you exercise, do so with caution and stay hydrated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause significant drowsiness, which may impair your ability to perform tasks that require alertness, such as driving, operating machinery, or working at heights. It is advisable to take it at bedtime if possible to minimize daytime sedation. Discuss with your employer if your job requires high alertness.
🛑 When to Stop This Medicine
Do not stop taking this medicine abruptly without consulting your doctor, especially if you have been taking it for a long time. Your doctor may recommend a gradual dose reduction to prevent withdrawal symptoms. If you experience serious side effects, seek medical advice immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance, meaning the effects may diminish over time. It can also cause dependence and withdrawal symptoms if stopped abruptly. Prolonged use may increase the risk of tardive dyskinesia and other movement disorders. Regular monitoring by a doctor is recommended for long-term therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Non-sedating antihistamines like cetirizine or loratadine can be used for allergic conditions with less drowsiness.
Evidence: Well-establishedFor anxiety, therapy can be an effective alternative or complement to medication.
Evidence: Well-establishedIdentifying and avoiding allergens can reduce the need for medication.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for allergy testing, inform your doctor, as antihistamines can interfere with skin test results. You may need to stop this medicine a few days before the test.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it in your carry-on luggage to avoid extreme temperatures. If crossing time zones, consult your doctor about adjusting the dosing schedule. Do not expose the medicine to direct sunlight or high heat.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The sedative effects usually begin within 15 to 30 minutes, while antihistamine effects may take 30 to 60 minutes.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal or snack.
A: No, this medicine can cause drowsiness and impair your ability to drive. Avoid driving until you know how it affects you.
A: Consult your doctor. This medicine is Pregnancy Category C and should be used only if clearly needed.
A: Seek emergency medical attention immediately. Overdose can cause severe drowsiness, seizures, and heart problems.
🤔 Common Patient Concerns
🔄 Substitutes for calmer 10mg syrup
View AllAlternative brands with exact same active ingredient:
-
biorex syrupJK Biochem Healthcare Pvt Ltd ₹42.19 18.2% CHEAPER
-
alrax 10mg syrupSG Lifecare Pvt Ltd ₹46.88 9.1% CHEAPER
-
xtrex 10mg syrupBest Biotech ₹51.56 SAME PRICE
-
prugain drops honeyHermes Therapeutics Pvt Ltd. ₹54.38 5.5% COSTLIER
-
unihyzi syrupUniza Healthcare LLP ₹56.25 9.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe to take with alcohol.
Fact: No, alcohol can increase drowsiness and other side effects. Avoid alcohol while taking this medicine. - Myth: This medicine is not habit-forming.
Fact: While not typically addictive, prolonged use can lead to tolerance and psychological dependence. Use only as prescribed. - Myth: This medicine can be used for a runny nose due to a cold.
Fact: This medicine is for allergic rhinitis, not the common cold. It may not be effective for cold symptoms.
🔄 Alternative Options
Generic Alternatives
- Hydroxyzine hydrochloride syrup
- Hydroxyzine pamoate suspension
Brand Alternatives
- Atarax
- Vistaril
- Aterax
- Hydroxyzine HCl