cadvion o3 180 mg/120 mg capsule - Eicosapentaenoic acid (180mg) + Docosahexanoic acid(DHA) (120mg) medicine

cadvion o3 180 mg/120 mg capsule - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Merck Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is cadvion o3 180 mg/120 mg capsule used for?

Com 6 Capsule (Omega-3 fatty acids (Eicosapentaenoic Acid and Docosahexaenoic Acid)) is used to treat VITAMINS MINERALS NUTRIENTS. It contains Eicosapentaenoic acid (180mg) + Docosahexanoic acid(DHA) (120mg), which Replaces arachidonic acid in cell membranes, reducing production of pro-inflamma. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Omega-3 fatty acids (Eicosapentaenoic Acid and Docosahexaenoic Acid)
  • Manufacturer: Merck Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š cadvion o3 180 mg/120 mg capsule Uses & Benefits

Hypertriglyceridemia, secondary prevention of cardiovascular disease, rheumatoid arthritis, inflammatory conditions.

Off-label uses: Depression, ADHD, Alzheimer's disease, dry eye syndrome.

๐Ÿ“‹ Drug Information

Generic Name(s)Omega-3 fatty acids (Eicosapentaenoic Acid and Docosahexaenoic Acid)
Brand NameCom 6 Capsule
ManufacturerMerck Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action ClassOmega-3 fatty acids
Route of AdministrationOral.
StorageStore at room temperature (20-25ยฐC) away from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed in the small intestine after hydrolysis by pancreatic lipases; absorption is enhanced when taken with dietary fat.
DistributionIncorporated into cell membrane phospholipids; distributed to tissues including brain, retina, and heart.
Protein BindingHighly protein-bound (>99%) to albumin.
MetabolismPrimarily metabolized via beta-oxidation in the liver; also undergoes elongation and desaturation.
Half-LifeApproximately 8-10 hours for EPA and DHA.
ExcretionExcreted as carbon dioxide via lungs and as metabolites in urine and feces.
BioavailabilityVariable; approximately 30-50% when taken with food.
Onset of ActionSeveral weeks to months for therapeutic effects.
Peak Plasma Time5-7 hours after oral administration.
Duration of ActionSustained with regular dosing; effects persist for weeks after discontinuation.

How It Works

Replaces arachidonic acid in cell membranes, reducing production of pro-inflammatory eicosanoids; also activates PPAR-alpha and reduces triglyceride synthesis.

Mechanism Steps

1Inhibition of diacylglycerol acyltransferase (DGAT) reducing triglyceride synthesis
2Increased beta-oxidation of fatty acids in the liver
3Reduced production of pro-inflammatory eicosanoids from arachidonic acid

๐Ÿ’ก How to Take cadvion o3 180 mg/120 mg capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cadvion o3 180 mg/120 mg capsule

โœ… Common Side Effects

  • Fishy aftertaste
  • Nausea
  • Diarrhea
  • Belching
  • Dyspepsia

๐Ÿšจ Serious Side Effects

  • Bleeding
  • Hemorrhagic stroke
  • Atrial fibrillation (rare)

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Liver enzyme elevation
  • Rash

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Anticoagulants Major Increased bleeding risk
Antiplatelet drugs Major Increased bleeding risk
Orlistat Moderate Reduced absorption of omega-3 fatty acids
Vitamin E supplements Moderate Possible additive antioxidant effects
Cyclosporine Minor May increase cyclosporine levels
Tacrolimus Minor May increase tacrolimus levels

๐Ÿšจ Major Interactions

  • Warfarin
  • Anticoagulants
  • Antiplatelet drugs

โšก Moderate Interactions

  • Orlistat
  • Vitamin E supplements

โ„น๏ธ Minor Interactions

  • Cyclosporine
  • Tacrolimus

๐Ÿฝ๏ธ Food Interactions

High-fat meals increase absorption, Grapefruit juice may reduce absorption

๐Ÿท Alcohol Interaction

No significant interaction; moderate alcohol consumption may increase triglyceride levels.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to fish or omega-3 fatty acids; active bleeding disorders.

๐Ÿ“Š Monitoring Parameters

Serum triglycerides, bleeding time, liver function tests.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; considered safe in moderate doses.

๐Ÿ’Š Overdose Management

Gastric lavage if recent; supportive care; monitor bleeding parameters.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

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