cadvion o3 180 mg/120 mg capsule - Eicosapentaenoic acid (180mg) + Docosahexanoic acid(DHA) (120mg) medicine

Com 6 Capsule: Omega-3 Supplement For Heart Health

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🏭 Merck Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 27, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Signs of allergic reaction such as rash, itching, or swelling of face, lips, or throat.
  • Unusual bleeding or bruising.
  • Severe abdominal pain.
  • Blood in stool or vomit.
  • Chest pain or difficulty breathing.
  • Yellowing of skin or eyes.

If experiencing severe symptoms, call emergency services immediately.

What is cadvion o3 180 mg/120 mg capsule used for?

This medicine is a combination of omega-3 fatty acids EPA and DHA used to lower triglycerides and support heart health.

  • Generic Name: Omega-3 fatty acids (Eicosapentaenoic Acid and Docosahexaenoic Acid)
  • Manufacturer: Merck Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cadvion o3 180 mg/120 mg capsule के बारे में (Hindi Summary)

उपयोग: यह दवा ओमेगा-3 फैटी एसिड का संयोजन है जो ट्राइग्लिसराइड को कम करने और हृदय स्वास्थ्य का समर्थन करने में मदद करती है। इसका उपयोग रुमेटॉइड गठिया में सूजन कम करने के लिए भी किया जा सकता है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मछली जैसा स्वाद, मतली, पेट में परेशानी और दस्त शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी या रक्तस्राव की समस्या हो सकती है।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी दवाओं और स्वास्थ्य स्थितियों के बारे में बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। इसे ठंडी और सूखी जगह पर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 cadvion o3 180 mg/120 mg capsule Uses & Benefits

[{"condition":"Hypertriglyceridemia","description":"This medicine helps lower elevated triglyceride levels in the blood, reducing the risk of cardiovascular complications.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"The omega-3 fatty acids in this medicine may reduce joint pain and stiffness by modulating inflammatory responses.","evidence":"Moderate"},{"condition":"Cardiovascular health support","description":"This medicine supports overall heart health by improving lipid profiles and reducing inflammation.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Depression","description":"Some studies suggest omega-3 supplementation may help improve symptoms of depression, but evidence is not definitive.","evidence":"Limited"},{"condition":"Age-related macular degeneration","description":"Omega-3 fatty acids may slow the progression of AMD, though more research is needed.","evidence":"Limited"}]

Primary treatment for: Hypertriglyceridemia

Also treats: Rheumatoid arthritis, Cardiovascular disease

📋 Drug Information

Generic Name(s)Omega-3 fatty acids (Eicosapentaenoic Acid and Docosahexaenoic Acid)
Brand NameCom 6 Capsule
ManufacturerMerck Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action ClassOmega-3 fatty acids
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with meals to improve absorption and reduce stomach upset.
2
Inform your doctor if you are taking blood thinners, as this medicine may increase bleeding risk.
3
Do not exceed the recommended dose unless advised by your doctor.
4
If you experience any allergic reactions, stop the medicine and seek medical help immediately.
5
Store the capsules in a cool, dry place away from direct sunlight.
6
Consult your doctor before starting this medicine if you are pregnant or breastfeeding.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High triglycerides
This medicine is commonly prescribed for this.
Likely Use
✅
Joint pain
May help with inflammation.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionEPA and DHA are absorbed in the small intestine. Absorption is enhanced when taken with a meal containing fat. The bioavailability of these fatty acids from this medicine is generally good, but may vary depending on the formulation and food intake.
DistributionAfter absorption, EPA and DHA are transported in the blood bound to lipoproteins and albumin. They are distributed to various tissues, including the liver, heart, brain, and retina, where they incorporate into cell membranes.
Protein BindingNot established from the available information.
MetabolismEPA and DHA are metabolized primarily in the liver through beta-oxidation and other pathways. They can also be converted to bioactive metabolites such as resolvins and protectins.
Half-LifeNot established from the available information.
ExcretionMetabolites of EPA and DHA are excreted mainly in the bile and urine, and some may be exhaled as carbon dioxide.
BioavailabilityThe bioavailability of EPA and DHA from this medicine is influenced by the presence of dietary fat. Taking it with food increases absorption.
Onset of ActionThe onset of action for triglyceride lowering may take several weeks of consistent use. Anti-inflammatory effects may also take weeks to become noticeable.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effects of this medicine persist as long as it is taken regularly. Triglyceride levels may return to baseline within weeks after discontinuation.

How It Works

This medicine works by delivering eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) to the body. These omega-3 fatty acids are incorporated into cell membranes, where they influence the production of eicosanoids and other signaling molecules. EPA competes with arachidonic acid for cyclooxygenase and lipoxygenase enzymes, leading to reduced formation of pro-inflammatory mediators. DHA is important for brain and retinal function and also contributes to anti-inflammatory effects. Together, they help lower triglyceride synthesis in the liver and support cardiovascular health.

Mechanism Steps

1
Incorporation into cell membranes: EPA and DHA from this medicine are absorbed and incorporated into phospholipid membranes of cells throughout the body.
2
Modulation of eicosanoid production: EPA competes with arachidonic acid for enzymes, leading to production of less inflammatory eicosanoids.
3
Reduction of hepatic triglyceride synthesis: Omega-3 fatty acids reduce the activity of enzymes involved in triglyceride synthesis in the liver, lowering blood triglyceride levels.
4
Anti-inflammatory effects: DHA and EPA reduce the production of pro-inflammatory cytokines and other mediators.

💡 How to Take cadvion o3 180 mg/120 mg capsule

Strength: Capsule containing Eicosapentaenoic Acid 180 mg and Docosahexaenoic Acid 120 mg.

1Take this medicine orally with a full glass of water.
2Swallow the capsule whole; do not chew or crush.
3Take with meals to enhance absorption and reduce stomach upset.
4Follow the dosage schedule prescribed by your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one capsule once or twice daily, or as directed by your physician. The dose may be adjusted based on your condition and response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients, but caution is advised due to potential increased risk of bleeding.
Renal ImpairmentNo dose adjustment is required for patients with renal impairment.
Hepatic ImpairmentNo dose adjustment is required for patients with hepatic impairment, but monitoring is advised.
Maximum Daily DoseThe maximum recommended daily dose is 2 capsules, unless otherwise prescribed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Enhances absorption and reduces stomach upset.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cadvion o3 180 mg/120 mg capsule

✅ Common Side Effects

Fishy aftertaste (Common (5-10%))
Take with meals or freeze capsules to reduce taste.
Nausea (Common (5-10%))
Take with food. If persists, consult doctor.
Loose stools (Common (5-10%))
Usually resolves. Stay hydrated. Consult if severe.
Stomach discomfort (Common (5-10%))
Take with meals. Avoid taking on empty stomach.

🚨 Serious Side Effects

Allergic reaction (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, or difficulty breathing.
Increased bleeding tendency (Rare (<0.1%))
Report unusual bleeding or bruising to your doctor immediately.

⚠️ Rare Side Effects

Elevated liver enzymes
Regular monitoring may be needed if you have liver disease.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Aspirin Major
Clopidogrel Moderate
Orlistat Minor

🚨 Major Interactions

  • Warfarin
  • Aspirin

⚡ Moderate Interactions

  • Clopidogrel

🍷 Alcohol Interaction

Alcohol may increase the risk of bleeding when taken with this medicine. It is advisable to limit alcohol consumption while on this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to fish or any component of this medicine"]

⚠️ Warnings & Precautions

["Use with caution in patients with bleeding disorders.","Avoid in patients allergic to fish.","Consult doctor before surgery.","Not for children unless prescribed."]

🤱 Lactation Safety

It is not known if this medicine passes into breast milk. Consult your doctor before using while breastfeeding.

💊 Overdose Management

Overdose of this medicine is unlikely to cause serious effects. However, if you suspect an overdose, seek medical attention. Symptoms may include nausea, diarrhea, and increased bleeding tendency.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Before starting this medicine, inform your doctor if you have a bleeding disorder, are scheduled for surgery, or are taking anticoagulants or antiplatelet drugs. Do not exceed the recommended dose unless advised by your healthcare provider. Pregnant and breastfeeding women should consult their doctor before using this product. Store this medicine in a cool, dry place away from direct sunlight and out of reach of children. Do not use this product if the seal is broken or if the capsules are damaged. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Do not double the dose to catch up.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more prone to bleeding. Monitor for signs of bleeding and consult doctor regularly.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. The safety of this medicine during pregnancy is not well established.

🏥 Post-Surgery Considerations

Inform your surgeon if you are taking this medicine, as it may increase bleeding risk. It may need to be stopped before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, especially before any surgical dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight.
🥗
Exercise regularly.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Avoid smoking.
🧘
Limit alcohol consumption.

🏋️ Exercise Considerations

No specific exercise restrictions. However, if you experience unusual bleeding or bruising, consult your doctor before continuing strenuous activities.

🥗 Diet Recommendations

Include omega-3 rich foods like fish.
Reduce intake of saturated fats.
Stay hydrated.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or any unusual symptoms, avoid these activities until you feel better.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe. Regular monitoring of lipid profile and bleeding time may be advised. Consult your doctor for periodic evaluations.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Increasing intake of fatty fish and nuts can provide omega-3 fatty acids.

Evidence: Well-established
Regular exercise

Helps improve lipid profile and cardiovascular health.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Continue with your regular vaccination schedule.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place during travel. If crossing time zones, continue with your regular schedule as much as possible. Check customs regulations for supplements before traveling internationally.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 50-year-old man with high triglycerides
Started taking this medicine as prescribed by his doctor. After 3 months, his triglyceride levels dropped significantly. He took it with meals to avoid fishy aftertaste.
💡 Lesson: Consistent use with food improves tolerability and efficacy.
👤 A 45-year-old woman with rheumatoid arthritis
Added this medicine to her treatment regimen. She noticed reduced joint stiffness after 6 weeks. She informed her doctor about all her medications.
💡 Lesson: This medicine can complement arthritis treatment but requires patience and medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: It may take several weeks to see effects on triglyceride levels.

Q: Can I take it with other medicines?

A: Consult your doctor, especially if you take blood thinners.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cadvion o3 180 mg/120 mg capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can replace a healthy diet.
    Fact: It is a supplement and should be used alongside a balanced diet.
  • Myth: It causes immediate weight loss.
    Fact: It does not cause weight loss; it supports heart health.

🔄 Alternative Options

Generic Alternatives

  • Omega-3 fatty acid capsules

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"EPA 180 mg + DHA 120 mg","use":"Hypertriglyceridemia"},{"medicine":"Omega-3-acid ethyl esters","composition":"EPA + DHA","use":"Hypertriglyceridemia"}]

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