cachof 400mg tablet - Ofloxacin (400mg) medicine

Aloflox 400mg Tablet: Complete Medicine Guide

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🏭 Cachet Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (rash, hives, swelling of face or throat, difficulty breathing)
  • Blistering or peeling of skin
  • Signs of superinfection (new or worsening infection)
  • No improvement after a few days of use
  • Severe burning, itching, or redness at application site
  • Joint pain or swelling

If experiencing severe symptoms, call emergency services immediately.

What is cachof 400mg tablet used for?

This medicine is a topical antibiotic containing Ofloxacin 400mg, used to treat bacterial skin infections. It works by killing bacteria that cause infection. Apply as directed by your doctor, usually once or twice daily. Do not use on eyes or mucous membranes.

  • Generic Name: Ofloxacin
  • Manufacturer: Cachet Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cachof 400mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल एंटीबायोटिक है जिसमें ओफ्लोक्सासिन 400mg होता है। इसका उपयोग त्वचा और मुलायम ऊतकों के बैक्टीरियल संक्रमण के इलाज के लिए किया जाता है। यह घाव, जलन, अल्सर, इम्पेटिगो और फॉलिकुलिटिस जैसी स्थितियों में प्रभावी है। यह बैक्टीरिया को मारकर संक्रमण को रोकती है। इसे बाहरी उपयोग के लिए ही लगाया जाता है।

साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, लालिमा या सूखापन शामिल है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, त्वचा पर छाले, या सूजन हो सकती है। यदि कोई गंभीर प्रतिक्रिया हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का उपयोग केवल बाहरी त्वचा पर करें। आंखों, नाक और मुंह से संपर्क से बचें। लगाने से पहले और बाद में हाथ धोएं। धूप में अधिक समय तक न रहें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 cachof 400mg tablet Uses & Benefits

[{"condition":"Infected wounds","description":"Used to treat bacterial infections in cuts, abrasions, and surgical wounds.","evidence":"Well-established"},{"condition":"Burns with secondary infection","description":"Helps prevent or treat bacterial infection in burn wounds.","evidence":"Well-established"},{"condition":"Skin ulcers","description":"Effective against infected pressure ulcers and diabetic foot ulcers.","evidence":"Well-established"},{"condition":"Impetigo","description":"Treats superficial skin infections caused by Staphylococcus aureus or Streptococcus pyogenes.","evidence":"Well-established"},{"condition":"Folliculitis","description":"Used for bacterial infection of hair follicles.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Acne vulgaris","description":"Sometimes used topically for inflammatory acne due to its antibacterial effect.","evidence":"Limited"},{"condition":"Prevention of infection in minor cuts","description":"May be applied to minor cuts to prevent bacterial infection.","evidence":"Limited"}]

Primary treatment for: Bacterial skin infections

Also treats: Infected wounds, Burns, Skin ulcers, Impetigo, Folliculitis

📋 Drug Information

Generic Name(s)Ofloxacin
Brand NameAuroflox 0.3% Eye Drop
ManufacturerCachet Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassQuinolones/ Fluroquinolones
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from light and moisture. Keep the container tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine exactly as prescribed by your doctor.
2
Wash your hands before and after applying to prevent contamination.
3
Do not use this medicine on your eyes, nose, or mouth.
4
Complete the full course even if symptoms improve to prevent resistance.
5
Avoid sun exposure and use sunscreen while using this medicine.
6
If you experience severe irritation or allergic reaction, stop use and consult your doctor.
7
Do not share this medicine with others.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Redness and swelling of skin
This medicine is commonly prescribed for bacterial skin infections.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Itching without infection
This medicine is not for allergic itching.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption following topical application is minimal. However, absorption may occur through broken skin or if applied to large areas. Not established from the available information for this specific formulation.
DistributionNot established from the available information for topical ofloxacin.
Protein BindingNot established from the available information for topical ofloxacin.
MetabolismNot established from the available information for topical ofloxacin.
Half-LifeNot established from the available information for topical ofloxacin.
ExcretionNot established from the available information for topical ofloxacin.
BioavailabilityNot established from the available information for topical ofloxacin.
Onset of ActionNot established from the available information for topical ofloxacin.
Peak Plasma TimeNot established from the available information for topical ofloxacin.
Duration of ActionNot established from the available information for topical ofloxacin.

How It Works

Ofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV. These enzymes are essential for DNA replication, transcription, repair, and recombination. By blocking these enzymes, ofloxacin prevents bacterial cell division and leads to bacterial death. It is bactericidal, meaning it kills bacteria directly. The topical formulation allows for high local concentrations at the site of infection while minimizing systemic absorption.

Mechanism Steps

1
Penetration into bacterial cell: Ofloxacin penetrates the bacterial cell wall and membrane to reach the cytoplasm.
2
Inhibition of DNA gyrase: Ofloxacin binds to DNA gyrase, preventing it from supercoiling DNA, which is necessary for replication.
3
Inhibition of topoisomerase IV: Ofloxacin also inhibits topoisomerase IV, which is involved in separating replicated DNA strands.
4
Blockage of DNA replication: The inhibition of these enzymes halts DNA replication and transcription, leading to bacterial cell death.

💡 How to Take cachof 400mg tablet

Strength: Topical formulation containing Ofloxacin 400mg

1Wash your hands thoroughly before and after applying the medicine.
2Clean and dry the affected area gently.
3Apply a thin layer of the medicine to the affected area.
4Rub it in gently if directed, or leave as a thin film.
5Do not cover with airtight dressings unless instructed.
6Avoid contact with eyes, nose, and mouth.
7Use at the same time(s) each day as prescribed.

Dosage Information

Adult DosageApply a thin layer to the affected area as directed by your physician, usually once or twice daily. The duration of treatment depends on the type and severity of the infection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are required for elderly patients when used topically. However, elderly patients may be more susceptible to skin irritation. Consult your doctor.
Renal ImpairmentNo dosage adjustment is required for topical use in patients with renal impairment.
Hepatic ImpairmentNo dosage adjustment is required for topical use in patients with hepatic impairment.
Maximum Daily DoseNot established from the available information. Use as prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of cachof 400mg tablet

✅ Common Side Effects

Application site burning (Common (1-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Application site itching (Common (1-10%))
Avoid scratching. Consult your doctor if it worsens.
Application site redness (Common (1-10%))
May indicate irritation. Discontinue if severe and consult your doctor.
Application site dryness (Common (1-10%))
Use a moisturizer if needed. Consult your doctor if it persists.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, hives, swelling of face or throat, difficulty breathing, or dizziness.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Rare (<0.1%))
Stop using and seek immediate medical attention if you notice blistering, peeling, or sores in mouth or eyes.
Superinfection (Rare (<0.1%))
Consult your doctor if you notice new or worsening infection, such as fungal overgrowth.

⚠️ Rare Side Effects

Photosensitivity
Avoid sun exposure and use sunscreen. Consult your doctor if you notice skin discoloration.
Tendonitis
Discontinue use and consult your doctor if you experience joint pain or swelling.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other topical antibiotics Major
Topical corticosteroids Moderate
Moisturizers Minor

🚨 Major Interactions

  • Other topical antibiotics

⚡ Moderate Interactions

  • Corticosteroids (topical)

🍷 Alcohol Interaction

No known interaction with alcohol when used topically. However, alcohol consumption may affect overall health and wound healing. Consult your doctor for personalized advice.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ofloxacin or other fluoroquinolones","Application to the eye or mucous membranes","Use on large areas of broken skin without medical supervision"]

⚠️ Warnings & Precautions

["For external use only.","Avoid contact with eyes, nose, and mouth.","Do not use on deep puncture wounds, animal bites, or serious burns without medical advice.","Discontinue if irritation or allergic reaction occurs.","Prolonged use may lead to bacterial resistance.","Avoid excessive sun exposure.","Keep out of reach of children."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before use.

💊 Overdose Management

Overdose from topical application is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, and dizziness. Treatment is symptomatic and supportive.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes. Wash hands thoroughly before and after applying this medicine. Do not apply to large areas of broken skin or open wounds without medical supervision. Do not cover the treated area with airtight dressings unless instructed by a doctor. Avoid exposure to excessive sunlight or artificial UV light (tanning beds) while using this medicine, as it may cause photosensitivity. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children. Do not use this medicine for longer than prescribed, as it may lead to bacterial resistance. If symptoms do not improve within a few days or worsen, consult your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have thinner skin and are more prone to irritation. Use with caution and monitor for side effects.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are planning pregnancy or are pregnant.

🏥 Post-Surgery Considerations

May be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions.

🦷 Dental Procedures

No specific considerations for dental procedures. Inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid scratching or picking at the infected area.
😴
Maintain good hygiene to prevent spread of infection.
💧
Eat a balanced diet to support healing.
🧘
Avoid sharing personal items like towels.
🌞
Manage underlying conditions like diabetes.

🏋️ Exercise Considerations

Avoid strenuous exercise that may cause friction or sweating over the treated area. Keep the area clean and dry after exercise.

🥗 Diet Recommendations

Include protein-rich foods to promote healing.
Stay hydrated.
Avoid excessive sugar intake as it may impair healing.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or vision changes, avoid these activities until you feel better.

🛑 When to Stop This Medicine

Stop using this medicine if you experience a severe allergic reaction or if your doctor advises discontinuation. Do not stop prematurely even if symptoms improve, as this may lead to recurrence.

📅 Long-Term Use Effects

Prolonged use of topical antibiotics may lead to bacterial resistance and superinfection. Use only as prescribed and for the recommended duration. If used for extended periods, monitor for signs of resistance or fungal overgrowth.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Good wound care

Cleaning and dressing wounds properly can prevent infection.

Evidence: Well-established
Other topical antibiotics

Mupirocin or fusidic acid may be alternatives for certain infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, continue your regular application schedule. Declare it at customs if required. Keep it in your carry-on luggage to avoid loss.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with an infected cut on his hand
He was prescribed this medicine to apply twice daily. After 3 days, the redness and swelling reduced significantly. He completed the 7-day course and the wound healed completely. He noted that washing hands before application was key.
💡 Lesson: Consistent application and good hygiene lead to effective healing.
👤 A 50-year-old woman with a diabetic foot ulcer
She used this medicine as part of her wound care regimen. The infection cleared within a week, and she continued to monitor her blood sugar levels. She emphasized the importance of not skipping doses.
💡 Lesson: Adherence to the prescribed regimen and managing underlying conditions improve outcomes.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start seeing improvement within a few days. Complete the full course as prescribed.

Q: Can I use this medicine on my face?

A: Consult your doctor before using on the face. Avoid contact with eyes and mucous membranes.

Q: What if I miss a dose?

A: Apply as soon as you remember. If it's almost time for the next dose, skip the missed dose and continue your schedule.

Q: Is it safe during pregnancy?

A: Consult your doctor before use. The safety profile for topical ofloxacin in pregnancy is not well established.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How long should I use this medicine?
  • What if I miss a dose?
  • Can I use other creams while using this medicine?
  • Is it safe for children?
  • Can I take this medicine if I am pregnant?

🔄 Substitutes for cachof 400mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any skin problem.
    Fact: It is only effective against bacterial infections. It does not treat viral or fungal infections.
  • Myth: You can stop using it as soon as symptoms improve.
    Fact: You should complete the full course as prescribed to prevent recurrence and resistance.
  • Myth: More medicine means faster healing.
    Fact: Applying more than prescribed can cause irritation and does not speed up healing.

🔄 Alternative Options

Generic Alternatives

  • Ofloxacin topical cream
  • Ofloxacin topical ointment

Brand Alternatives

  • Aloflox 400mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Ofloxacin topical","class":"Fluoroquinolone","spectrum":"Broad","common_use":"Skin infections"},{"medicine":"Mupirocin topical","class":"Mupirocin","spectrum":"Gram-positive","common_use":"Impetigo"},{"medicine":"Fusidic acid topical","class":"Fusidane","spectrum":"Gram-positive","common_use":"Skin infections"}]

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