Abdopime 500mg Injection (Cefepime): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe watery diarrhea or bloody stools
- Confusion, hallucinations, or seizures
- Decreased urine output or swelling in the legs
- Unusual bruising or bleeding
- Severe skin rash with blisters or peeling
- High fever with chills that does not improve
If experiencing severe symptoms, call emergency services immediately.
What is cachepime 500mg injection used for?
This medicine is a fourth-generation cephalosporin antibiotic given by injection to treat serious bacterial infections. It works by breaking down the bacterial cell wall, causing the bacteria to die. It is used for infections of the urinary tract, lungs, skin, abdomen, and bloodstream, and for fever with low white blood cell counts. It must be given by a healthcare professional and is not for self-administration.
- Generic Name: Cefepime (500mg)
- Manufacturer: Cachet Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cachepime 500mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफेपाइम नामक एक शक्तिशाली एंटीबायोटिक है जो इंजेक्शन के रूप में दी जाती है। यह शरीर में गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए इस्तेमाल की जाती है, जैसे कि मूत्र मार्ग का संक्रमण, निमोनिया, त्वचा का संक्रमण, पेट का संक्रमण, और खून का संक्रमण। यह दवा बुखार और कम सफेद रक्त कोशिकाओं वाले मरीजों में भी दी जाती है। यह बैक्टीरिया की कोशिका भित्ति को तोड़कर उन्हें मार देती है। यह दवा केवल डॉक्टर या नर्स द्वारा अस्पताल या क्लिनिक में ही दी जानी चाहिए। इसे खुद से नहीं लगाना चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में इंजेक्शन वाली जगह पर दर्द, लालिमा या सूजन, दस्त, जी मिचलाना, उल्टी, सिरदर्द, चकत्ते और बुखार शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें तेज एलर्जी, त्वचा पर गंभीर प्रतिक्रिया, आंत का संक्रमण, भ्रम या दौरे, और गुर्दे की समस्या शामिल हो सकती है। अगर आपको सांस लेने में तकलीफ, चेहरे या गले में सूजन, गंभीर दस्त, या भ्रम महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में डॉक्टर या नर्स द्वारा ही दी जानी चाहिए। इससे पहले कि आपको यह दवा दी जाए, अपने डॉक्टर को अपनी सभी एलर्जी के बारे में बताएं, खासकर पेनिसिलिन या सेफलोस्पोरिन एंटीबायोटिक्स से। अगर आपको गुर्दे या लीवर की बीमारी है या दौरे पड़ते हैं, तो डॉक्टर को जरूर बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। इलाज के दौरान शराब न पिएं। दवा का पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। नियमित जांच के लिए डॉक्टर के पास जाएं।
💊 cachepime 500mg injection Uses & Benefits
[{"condition":"Complicated urinary tract infections","description":"Used to treat serious kidney and bladder infections caused by susceptible bacteria, including those resistant to other antibiotics.","evidence":"Well-established"},{"condition":"Pneumonia","description":"Prescribed for moderate to severe community-acquired and hospital-acquired pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Effective against complicated skin infections, including cellulitis and abscesses caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Used in combination with other antibiotics for complicated intra-abdominal infections such as peritonitis.","evidence":"Well-established"},{"condition":"Febrile neutropenia","description":"Given as empirical therapy to patients with fever and low white blood cell counts, often after chemotherapy.","evidence":"Well-established"},{"condition":"Bacteremia","description":"Used to treat bloodstream infections caused by susceptible gram-negative and gram-positive bacteria.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Meningitis","description":"Sometimes used off-label for bacterial meningitis when other options are not suitable, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Prosthetic joint infections","description":"Occasionally used off-label as part of combination therapy for prosthetic joint infections, guided by culture results.","evidence":"Limited"}]
Primary treatment for: Bacterial infections caused by susceptible organisms
Also treats: Complicated urinary tract infections, Pneumonia, Skin and soft tissue infections, Intra-abdominal infections, Febrile neutropenia, Bacteremia
📋 Drug Information
| Generic Name(s) | Cefepime (500mg) |
| Brand Name | cachepime 500mg injection |
| Manufacturer | Cachet Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 4th generation |
| Route of Administration | Parenteral (intravenous or intramuscular injection). This medicine is given by a healthcare professional in a hospital or clinic setting |
| Storage | Store the unreconstituted powder at room temperature between 20°C and 25°C (68°F to 77°F). Protect it from light and moisture. After reconstitution, the solution should be used within the time specified by the manufacturer, usually within a few hours if kept at room temperature or up to 24 hours if refrigerated. Do not freeze the reconstituted solution. |
| Shelf Life | The shelf life of the unreconstituted powder is typically 24 months from the date of manufacture. Check the expiry date on the vial before use. Once reconstituted, use the solution within the recommended time frame. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a beta-lactam antibiotic that kills bacteria by interfering with the construction of the bacterial cell wall. It binds to specific proteins called penicillin-binding proteins located on the inner membrane of the bacterial cell. This binding blocks the cross-linking of peptidoglycan chains, which are essential for the strength and shape of the cell wall. Without a proper cell wall, the bacteria cannot maintain their structure and they burst and die. Because this medicine has a broad spectrum, it can attach to many different penicillin-binding proteins in both gram-positive and gram-negative bacteria, making it effective against a wide range of organisms.
Mechanism Steps
💡 How to Take cachepime 500mg injection
Strength: This medicine is supplied as a sterile powder for injection containing 500 mg of cefepime in each vial. It must be reconstituted with a suitable diluent before use.
Dosage Information
| Adult Dosage | The dose of this medicine is determined by your doctor based on the type and severity of the infection, your kidney function, and your body weight. For many serious infections, a common adult dose is 1 gram to 2 grams given intravenously every 8 to 12 hours. For uncomplicated urinary tract infections, a lower dose such as 500 mg to 1 gram every 12 hours may be used. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never self-administer this medicine. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific 500 mg injection presentation. In general, pediatric doses are calculated based on body weight and are given under the supervision of a pediatrician. Consult a pediatrician for appropriate dosing. |
| Elderly Dosage | Elderly patients may have reduced kidney function, which can cause this medicine to build up in the body and increase the risk of side effects, especially confusion and seizures. Your doctor will check your kidney function and adjust the dose accordingly. Older adults should be monitored closely during treatment. |
| Renal Impairment | Patients with kidney impairment need a lower dose or a longer time between doses. Your doctor will calculate the correct dose based on your creatinine clearance. For example, if your creatinine clearance is between 30 and 60 mL/min, the dose may be given every 12 hours instead of every 8 hours. If your creatinine clearance is less than 30 mL/min, the dose may be given every 24 hours. Patients on dialysis may need a dose after each dialysis session. Always follow your doctor's instructions. |
| Hepatic Impairment | No dose adjustment is needed for patients with liver disease alone, because this medicine is not significantly broken down by the liver. However, if you have both liver and kidney disease, your doctor will adjust the dose based on your kidney function. |
| Maximum Daily Dose | The maximum recommended daily dose is 6 grams per day, but this is only for severe infections in patients with normal kidney function. The exact maximum dose for you will be determined by your doctor based on your condition and kidney function. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cachepime 500mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Gentamicin | Major | |
| Furosemide | Major | |
| Warfarin | Major | |
| Probenecid | Moderate | |
| Amphotericin B | Moderate | |
| Vancomycin | Moderate | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Aminoglycosides (e.g., gentamicin, tobramycin)
- Loop diuretics (e.g., furosemide)
- Warfarin
⚡ Moderate Interactions
- Probenecid
- Other nephrotoxic drugs (e.g., amphotericin B, vancomycin)
🍷 Alcohol Interaction
It is best to avoid alcohol while receiving this medicine. Alcohol can increase the risk of stomach upset, dizziness, and liver strain, and it may make it harder for your body to fight the infection. If you drink alcohol regularly, tell your doctor so they can give you personalized advice.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergic reaction to cefepime or any other cephalosporin antibiotic","Known severe allergic reaction to penicillin or other beta-lactam antibiotics","Previous serious allergic reaction to any component of this medicine"]
⚠️ Warnings & Precautions
["Before starting this medicine, tell your doctor about all your allergies, especially to antibiotics.","Use with caution in patients with kidney disease; dose adjustment may be needed.","Use with caution in patients with a history of seizures or brain conditions.","Prolonged use can lead to overgrowth of bacteria that are not killed by this medicine, such as Candida.","This medicine may cause a serious gut infection called C. difficile-associated diarrhea; report any new diarrhea.","Do not use this medicine to treat viral infections like colds or flu.","Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Avoid alcohol during treatment.","Keep all follow-up appointments for monitoring."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is generally considered safe for breastfeeding mothers, but it can cause diarrhea or yeast infections in the nursing infant. Talk to your doctor before breastfeeding while receiving this medicine.
💊 Overdose Management
Overdose with this medicine can cause severe brain effects such as confusion, hallucinations, and seizures, especially in patients with kidney problems. If an overdose is suspected, stop the infusion and seek emergency medical help immediately. Treatment is supportive, and in severe cases, hemodialysis may be used to remove the medicine from the blood. There is no specific antidote.
⏰ Missed Dose
Because this medicine is given by a healthcare professional, a missed dose is unlikely. If you miss a scheduled dose at a clinic or hospital, contact your healthcare provider as soon as possible to reschedule. Do not try to self-administer a double dose to make up for a missed one.
Additional Safety Advice
This medicine must only be given by a qualified healthcare professional in a hospital or clinic setting. Before receiving this medicine, tell your doctor about all your allergies, especially any allergy to penicillin or cephalosporin antibiotics. Inform your doctor if you have kidney disease, liver disease, or a history of seizures, because the dose may need adjustment. Do not breastfeed while receiving this medicine without first talking to your doctor, as it can pass into breast milk. If you are pregnant or planning to become pregnant, discuss the risks and benefits with your doctor. Avoid alcohol during treatment because it can worsen side effects and put extra stress on your liver. Do not stop treatment early even if you feel better, as this can allow the infection to return and lead to resistance. Keep all follow-up appointments so your doctor can monitor your kidney function, blood counts, and response to treatment.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can cause this medicine to build up and lead to confusion, hallucinations, or seizures. Your doctor will check your kidney function and adjust the dose. Older adults should be monitored closely for any changes in mental status or balance.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss this medicine with your doctor before starting treatment. This medicine is in Pregnancy Category B, but it should only be used if clearly needed. Your doctor will weigh the benefits and risks for you and your baby.
🏥 Post-Surgery Considerations
This medicine is often used after surgery to prevent or treat infections. If you have recently had surgery, tell your surgeon and anesthesiologist about all medicines you are taking. This medicine may interact with other drugs used during surgery, so your healthcare team will monitor you closely.
🦷 Dental Procedures
If you are scheduled for a dental procedure, tell your dentist that you are receiving this medicine. In some cases, your dentist may recommend delaying the procedure until you have completed treatment and recovered. This medicine does not typically interact with local anesthetics, but your dentist should be aware of your full medication list.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While receiving this medicine, you may feel tired or weak. Avoid strenuous exercise until you have recovered from the infection. Light activity such as walking is fine if you feel up to it. If you experience dizziness, confusion, or muscle weakness, do not exercise and contact your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital or clinic, so you may need to take time off work or arrange for transportation. You may feel tired or dizzy during treatment, so avoid driving or operating heavy machinery until you know how the medicine affects you. Most people can return to normal activities after completing treatment and recovering from the infection.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor will decide when to stop based on your response to treatment, the type of infection, and your test results. If you develop serious side effects such as a severe allergic reaction, kidney problems, or severe diarrhea, your doctor may stop the medicine and switch to a different treatment. Always consult your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to antibiotic resistance, overgrowth of fungi or other bacteria, and a higher risk of C. difficile infection. Prolonged treatment may also increase the chance of kidney or blood-related side effects. Your doctor will monitor your kidney function, blood counts, and clinical response regularly. If you need long-term therapy, your doctor will reassess the need periodically and may switch to a different antibiotic if necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Once you improve, your doctor may switch you to oral antibiotics to complete the treatment at home.
Evidence: Well-establishedIf you are allergic to cephalosporins or the infection is resistant, your doctor may choose a different class such as carbapenems or fluoroquinolones.
Evidence: Well-establishedRest, fluids, and fever control can help you feel better while the antibiotic works.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with most vaccines. However, if you are scheduled to receive a live vaccine, tell your doctor, as antibiotics generally do not affect vaccine safety but the infection itself may be a reason to delay vaccination. Follow your doctor's advice on vaccination timing.
📦 Storage Guide
✅ DO
Store the unreconstituted powder at room temperature (20-25°C)
❌ DON'T
Do not freeze the powder or the reconstituted solution
✅ DO
Keep the vial in its original carton to protect from light
❌ DON'T
Do not use if the powder is discolored or the vial is damaged
✅ DO
Use the reconstituted solution within the recommended time
❌ DON'T
Do not store reconstituted solution for more than 24 hours in the refrigerator
✈️ Traveling with This Medicine
If you need to travel while receiving this medicine, it must be administered by a healthcare professional at your destination. Carry a copy of your prescription and a letter from your doctor explaining your medical condition and the need for this medicine. Keep the medicine in its original packaging and store it as directed. If you are traveling across time zones, your doctor will adjust the dosing schedule to maintain proper blood levels. Check with the airline and local authorities about carrying injectable medicines. Never pack it in checked luggage; keep it in your carry-on with your prescription.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 48 hours after starting treatment, but it can take a few days for the full effect. It is important to complete the entire course prescribed by your doctor.
A: No, this medicine is an injectable antibiotic that must be given by a healthcare professional in a hospital or clinic. It is not for self-administration at home.
A: Tell your doctor about any diarrhea, especially if it is watery, bloody, or accompanied by fever or stomach cramps. Do not treat it with over-the-counter anti-diarrheal medicines without asking your doctor first.
A: This medicine is in Pregnancy Category B, which means animal studies have not shown a risk, but there are not enough studies in pregnant women. It should be used only if clearly needed and after discussing with your doctor.
A: Yes, in rare cases, especially in elderly patients or those with kidney problems, this medicine can cause confusion, hallucinations, or seizures. If you experience any of these symptoms, tell your doctor immediately.
🤔 Common Patient Concerns
🔄 Substitutes for cachepime 500mg injection
View AllAlternative brands with exact same active ingredient:
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biopime 500mg injectionBiochem Pharmaceutical Industries ₹64.85 73% CHEAPER
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cepime 500mg injectionAlembic Pharmaceuticals Ltd ₹67.41 71.9% CHEAPER
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natapime 500mg injectionAncalima Lifesciences Ltd ₹80.00 66.7% CHEAPER
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maxopime 500mg injectionParenteral Drugs India Ltd ₹80.79 66.3% CHEAPER
-
cefeprime 500mg injectionVeritaz Healthcare Ltd ₹83.13 65.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any infection.
Fact: This medicine only works against certain bacteria. It does not treat viral infections like colds or flu. - Myth: You can stop this medicine as soon as you feel better.
Fact: You must complete the full course prescribed by your doctor to prevent the infection from returning and to avoid antibiotic resistance. - Myth: This medicine is safe to use without a doctor's supervision.
Fact: This medicine is a prescription injectable antibiotic and must only be given by a healthcare professional. - Myth: This medicine is the same as penicillin.
Fact: This medicine belongs to the cephalosporin family, which is related to but different from penicillin. Some people allergic to penicillin may also be allergic to this medicine.
🔄 Alternative Options
Generic Alternatives
- Cefepime 500 mg injection
Brand Alternatives
- Abdopime 500mg injection