caceff tablet - Cefalexin (250mg) + Carbocisteine (150mg) medicine

Caceff Tablet: Complete Medicine Guide

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🏭 Lupin Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Cefalexin: Well-established; Carbocisteine: Moderate for mucolytic effect.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Severe or bloody diarrhoea

If experiencing severe symptoms, call emergency services immediately.

What is caceff tablet used for?

This medicine is a combination of cefalexin (an antibiotic) and carbocisteine (a mucolytic) used to treat bacterial respiratory tract infections with thick mucus. It works by killing bacteria and thinning mucus, making it easier to cough up. It is available as an immediate-release tablet and must be taken as prescribed by a doctor.

  • Generic Name: Cefalexin + Carbocisteine
  • Manufacturer: Lupin Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 caceff tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सेफालेक्सिन और कार्बोसिस्टीन का संयोजन है, जिसका उपयोग बैक्टीरियल श्वसन संक्रमण के इलाज के लिए किया जाता है, खासकर जब बलगम गाढ़ा हो और निकलने में कठिनाई हो। यह दवा बैक्टीरिया को मारती है और बलगम को पतला करके बाहर निकालने में मदद करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, या गंभीर त्वचा पर दाने हों तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। दवा को पानी के साथ लें, और यदि पेट में जलन हो तो भोजन के साथ लें। शराब का सेवन न करें। गुर्दे या यकृत की समस्या हो तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 caceff tablet Uses & Benefits

[{"condition":"Acute bacterial bronchitis","description":"Used to treat bacterial infection of the bronchi, especially when associated with thick mucus production.","evidence":"Well-established for cefalexin; carbocisteine is used as an adjunct for mucus clearance."},{"condition":"Acute exacerbation of chronic bronchitis","description":"Helps in managing bacterial exacerbations in patients with chronic obstructive pulmonary disease (COPD) or chronic bronchitis.","evidence":"Well-established for cefalexin; carbocisteine is commonly added for symptomatic relief."},{"condition":"Respiratory tract infections with mucus congestion","description":"Prescribed for infections like pneumonia or sinusitis when thick mucus is a prominent feature.","evidence":"Cefalexin is effective against susceptible bacteria; carbocisteine aids in mucus clearance."}]

Off-label uses: [{"condition":"Otitis media","description":"Cefalexin is sometimes used for ear infections, but the combination with carbocisteine is not standard.","evidence":"Limited for the combination; cefalexin alone may be used."},{"condition":"Urinary tract infections","description":"Cefalexin is used for UTIs, but carbocisteine has no role here.","evidence":"Not established for the combination."}]

Primary treatment for: Bacterial respiratory tract infections with mucus congestion

Also treats: Acute bronchitis, Chronic bronchitis exacerbation, Pneumonia, Sinusitis

📋 Drug Information

Generic Name(s)Cefalexin + Carbocisteine
Brand NameCaceff Tablet
ManufacturerLupin Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporin antibiotic + Mucolytic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full prescribed course even if you feel better after a few days.
3
Stay well hydrated to help loosen mucus.
4
Avoid alcohol while taking this medicine as it may worsen stomach irritation.
5
Inform your doctor if you have kidney or liver problems before taking this medicine.
6
Do not share this medicine with others, even if they have similar symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
✅
Fever
If fever is due to bacterial infection, this medicine may help.
Likely Use
❌
Viral cold
This medicine is not effective against viruses.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefalexin is well absorbed from the gastrointestinal tract after oral administration. Carbocisteine is also absorbed orally. Food may slightly delay absorption but does not significantly affect the extent.
DistributionCefalexin distributes widely into body tissues and fluids, including the respiratory tract. Carbocisteine distributes to respiratory secretions.
Protein BindingCefalexin is approximately 10-15% bound to plasma proteins. Carbocisteine binding is not well established.
MetabolismCefalexin is not significantly metabolized and is excreted largely unchanged in urine. Carbocisteine is metabolized in the liver to inactive metabolites.
Half-LifeThe elimination half-life of cefalexin is approximately 0.5 to 1.2 hours in adults with normal renal function. The half-life of carbocisteine is not well established.
ExcretionCefalexin is excreted primarily unchanged in the urine by glomerular filtration and tubular secretion. Carbocisteine is excreted mainly in the urine as metabolites.
BioavailabilityThe oral bioavailability of cefalexin is approximately 90% in fasting state. Bioavailability of carbocisteine is not well established.
Onset of ActionCefalexin begins to kill bacteria within a few hours, but clinical improvement may take 24-48 hours. Carbocisteine's mucolytic effect may start within hours.
Peak Plasma TimePeak plasma concentrations of cefalexin are reached about 1 hour after oral administration. Peak for carbocisteine is not well established.
Duration of ActionThe antibacterial effect of cefalexin lasts about 6-12 hours per dose. Carbocisteine's effect lasts several hours.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Cefalexin is a first-generation cephalosporin antibiotic that works by binding to penicillin-binding proteins (PBPs) on the bacterial cell wall, inhibiting the synthesis of peptidoglycan, which is essential for cell wall integrity. This leads to bacterial cell lysis and death. Carbocisteine is a mucolytic agent that reduces the viscosity of mucus by breaking down disulfide bonds in mucoproteins, thereby thinning secretions and making them easier to expectorate. Together, they address both the bacterial infection and the associated mucus congestion.

Mechanism Steps

1
Cefalexin binding to PBPs: Cefalexin binds to penicillin-binding proteins on the bacterial cell membrane, inhibiting cell wall synthesis.
2
Bacterial cell lysis: Inhibition of cell wall synthesis leads to weakening of the cell wall and eventual lysis of the bacteria.
3
Carbocisteine mucolysis: Carbocisteine breaks disulfide bonds in mucus glycoproteins, reducing mucus viscosity.
4
Enhanced mucus clearance: Thinned mucus is more easily cleared by cilia and coughing, helping to relieve congestion.

💡 How to Take caceff tablet

Strength: Each immediate-release tablet contains 250 mg cefalexin and 150 mg carbocisteine.

1Take the tablet with a full glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take with or without food, but with food if it upsets your stomach.
4Take at evenly spaced intervals as prescribed.
5Complete the full course even if you feel better.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally two to three times a day, or as prescribed by your doctor. The exact dose and duration depend on the type and severity of the infection, your kidney function, and your overall health. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Consult your doctor.
Renal ImpairmentDose adjustment is required in patients with renal impairment. Consult your doctor for appropriate dosing.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and consult your doctor.
Maximum Daily DoseThe maximum daily dose should not exceed the prescribed amount. Typically, cefalexin is not recommended to exceed 4 g per day. Carbocisteine maximum daily dose is not well established. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May worsen stomach irritation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of caceff tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If persistent, consult your doctor.
Diarrhoea (Common (5-10%))
Stay hydrated. If severe or bloody, seek medical advice.
Stomach pain (Common (5-10%))
Take with food. If severe, contact your doctor.
Skin rash (Uncommon (1-5%))
Stop the medicine and consult your doctor if rash develops.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Clostridioides difficile-associated diarrhoea (Rare (<0.1%))
Seek medical attention if you develop severe, persistent, or bloody diarrhoea.
Stevens-Johnson syndrome (Very rare (<0.01%))
Seek immediate medical care if you develop a painful rash with blistering and peeling skin.

⚠️ Rare Side Effects

Interstitial nephritis
Report decreased urine output or swelling to your doctor.
Hepatitis
Report yellowing of skin or eyes to your doctor.
Seizures
Seek immediate medical attention if seizures occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Aminoglycosides Major
Loop diuretics Moderate
Probenecid Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Aminoglycosides

⚡ Moderate Interactions

  • Loop diuretics
  • Probenecid

🍷 Alcohol Interaction

Alcohol may worsen stomach irritation and should be avoided while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cephalosporins or penicillins","Active peptic ulcer disease","Severe renal impairment (dose adjustment needed)","Porphyria"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; dose adjustment may be required.","Prolonged use may lead to overgrowth of non-susceptible organisms.","May cause false-positive results in urine glucose tests.","Avoid in patients with a history of penicillin allergy due to cross-reactivity.","Carbocisteine should be used with caution in patients with asthma or peptic ulcer."]

🤱 Lactation Safety

Cefalexin is excreted in breast milk in small amounts and is generally considered safe. Carbocisteine safety in breastfeeding is not well established. Consult your doctor.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhoea, and abdominal pain. In severe cases, seizures or renal impairment may occur. Treatment is supportive and symptomatic. Contact a poison control center or emergency department immediately if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop the course early, even if you feel better, as this can lead to antibiotic resistance. Take the tablet with a full glass of water, with or without food, but taking it with food may reduce stomach upset. Avoid alcohol while taking this medicine, as it may worsen stomach irritation. Inform your doctor if you have kidney or liver problems, as dose adjustment may be needed. Do not share this medicine with others, even if they have similar symptoms. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function and may require dose adjustment. Monitor for signs of toxicity.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Cefalexin is generally considered safe, but carbocisteine should be used with caution.

🏥 Post-Surgery Considerations

Consult your surgeon before taking this medicine after surgery, as it may interact with other medications or affect healing.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may affect bleeding risk or interact with other medications.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Get plenty of rest to support your immune system.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Use a humidifier to keep airways moist.
🧘
Practice good hand hygiene to prevent spreading infections.

🏋️ Exercise Considerations

Rest is important during an active infection. Avoid strenuous exercise until you feel better. Light activity like walking may be okay if tolerated.

🥗 Diet Recommendations

Drink warm fluids like soups and herbal teas.
Include fruits rich in vitamin C.
Avoid cold and sugary drinks that may thicken mucus.
Eat a balanced diet to support recovery.

💼 Impact on Daily Work & Life

You may feel tired or dizzy while taking this medicine. Avoid driving or operating heavy machinery if you experience these effects. Take rest as needed.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Complete the full prescribed course. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended unless prescribed for a specific chronic condition. Prolonged use of antibiotics can lead to bacterial resistance and secondary infections. Regular monitoring of kidney and liver function may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and relieve congestion.

Evidence: Well-established for symptomatic relief.
Saline nasal irrigation

Can help clear nasal passages.

Evidence: Well-established for sinus congestion.

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, antibiotics may reduce the effectiveness of live bacterial vaccines like typhoid vaccine. Consult your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust dosing times gradually as advised by your doctor. Keep it in your carry-on luggage to avoid loss. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with acute bronchitis and thick mucus
Ravi, a 45-year-old office worker, developed a severe cough with thick yellow mucus and fever. His doctor prescribed this medicine. Within three days, his cough became more productive and mucus thinner. He completed the seven-day course and recovered fully. He was advised to take the tablet with food to avoid stomach upset.
💡 Lesson: Taking the full course and staying hydrated helps clear the infection and mucus effectively.
👤 A 60-year-old with chronic bronchitis exacerbation
Mrs. Sharma, a 60-year-old with chronic bronchitis, experienced worsening cough and breathlessness. Her doctor prescribed this medicine along with other supportive care. She noticed improvement in mucus clearance after two days. She was monitored for kidney function due to her age and completed the course without any serious side effects.
💡 Lesson: Elderly patients should be monitored for renal function while on this medicine, and adherence to the prescribed course is crucial.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: Is this medicine safe in pregnancy?

A: Cefalexin is generally considered safe in pregnancy, but carbocisteine should be used with caution. Consult your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for caceff tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the common cold.
    Fact: This medicine contains an antibiotic (cefalexin) which is only effective against bacterial infections, not viruses.
  • Myth: You can stop taking this medicine once you feel better.
    Fact: You must complete the full prescribed course to prevent bacterial resistance and recurrence of infection.

🔄 Alternative Options

Generic Alternatives

  • Cefalexin + Carbocisteine combination generics may be available.

Brand Alternatives

  • Caceff Tablet is the brand name for this medicine.

📊 Comparison with Similar Medicines

[{"medicine":"Caceff Tablet","composition":"Cefalexin 250mg + Carbocisteine 150mg","class":"Cephalosporin antibiotic + Mucolytic","primary_use":"Respiratory tract infections with mucus"},{"medicine":"Amoxicillin + Carbocisteine","composition":"Amoxicillin 500mg + Carbocisteine 150mg","class":"Penicillin antibiotic + Mucolytic","primary_use":"Respiratory tract infections with mucus"}]

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