c psorin 100mg capsule
What is c psorin 100mg capsule used for?
Arpimune ME 50mg Capsule (Ciclosporin) is used to treat OPHTHAL. It contains Ciclosporin (100mg), which Inhibits calcineurin, thereby preventing dephosphorylation and nuclear transloca. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ciclosporin
- Manufacturer: Kaizen Research Labs India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ c psorin 100mg capsule Uses & Benefits
Prophylaxis of organ transplant rejection; rheumatoid arthritis; psoriasis; nephrotic syndrome; dry eye disease (ophthalmic).
Off-label uses: Severe atopic dermatitis; ulcerative colitis; aplastic anemia.
๐ Drug Information
| Generic Name(s) | Ciclosporin |
| Brand Name | Arpimune ME 50mg Capsule |
| Manufacturer | Kaizen Research Labs India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Immunosuppressant- Calcineurin inhibitors |
| Route of Administration | Oral |
| Storage | Store at 15-30ยฐC in a dry place; protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits calcineurin, thereby preventing dephosphorylation and nuclear translocation of nuclear factor of activated T-cells (NF-AT), leading to reduced transcription of interleukin-2 and other cytokines, suppressing T-cell activation.
Mechanism Steps
๐ก How to Take c psorin 100mg capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of c psorin 100mg capsule
โ Common Side Effects
- Nephrotoxicity
- Hypertension
- Tremor
- Hirsutism
- Gingival hyperplasia
- Gastrointestinal disturbances
- Hyperlipidemia
๐จ Serious Side Effects
- Acute or chronic nephrotoxicity
- Hepatotoxicity
- Neurotoxicity (seizures, encephalopathy)
- Lymphoma
- Opportunistic infections
- Thrombotic microangiopathy
โ ๏ธ Rare Side Effects
- Anaphylaxis
- Hemolytic uremic syndrome
- Pancreatitis
- Myopathy
- Gynecomastia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Potassium-sparing diuretics | Major | Increased risk of hyperkalemia |
| ACE inhibitors | Major | Increased risk of hyperkalemia and nephrotoxicity |
| NSAIDs | Major | Increased nephrotoxicity risk |
| Live vaccines | Major | Risk of disseminated infection |
| Ketoconazole | Moderate | Increased ciclosporin levels |
| Rifampin | Moderate | Decreased ciclosporin levels |
| Grapefruit juice | Minor | Increased ciclosporin levels |
๐จ Major Interactions
- Potassium-sparing diuretics
- ACE inhibitors
- ARBs
- Methotrexate
- Colchicine
- NSAIDs
- Live vaccines
โก Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
- CYP3A4 inducers (e.g., rifampin, phenytoin)
- Statins
- Digoxin
- Prednisolone
โน๏ธ Minor Interactions
- Grapefruit juice
- Calcium channel blockers (e.g., diltiazem, verapamil)
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Grapefruit juice increases bioavailability; avoid. Food may decrease absorption; take consistently with or without food.
๐ท Alcohol Interaction
Alcohol may increase hepatotoxicity risk; avoid excessive consumption.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to ciclosporin; uncontrolled hypertension; active infections; malignancy; concurrent PUVA or UVB therapy.
๐ Monitoring Parameters
Blood pressure, renal function (serum creatinine, BUN), liver function tests, ciclosporin trough levels, electrolytes (especially potassium), lipid profile.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Supportive care; monitor renal function, liver function, and electrolytes; no specific antidote.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for c psorin 100mg capsule
View AllAlternative brands with exact same active ingredient (Ciclosporin (100mg)):
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davaindia ciclosporin 100mg capsuleDavaindia Generic Pharmacy โน125.00 86% CHEAPER
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cyrin 100mg capsuleClaris Lifesciences Ltd โน455.86 48.8% CHEAPER
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imusporin 100 capsuleCipla Ltd โน460.00 48.3% CHEAPER
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imunet 100mg capsuleCytoz Pharmaceuticals โน480.00 46.1% CHEAPER
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arpimune-o 100mg capsuleRPG Life Sciences Ltd โน509.80 42.7% CHEAPER
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neoral 100mg capsuleNovartis India Ltd โน536.45 39.7% CHEAPER
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sandimmun neoral 100mg soft gelatin capsuleNovartis India Ltd โน541.28 39.2% CHEAPER
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iminoral 100 capsuleEmcure Pharmaceuticals Ltd โน541.36 39.2% CHEAPER
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cyclonox 100mg soft gelatin capsuleIndiabulls pharmaceutical ltd โน549.80 38.2% CHEAPER
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cyclophil me 100 capsuleBiocon โน550.41 38.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
Found this to be a helpful product. Good results.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.