c-gen cream
What is c-gen cream used for?
Cosvate-GM Cream (Clobetasol + Gentamicin) is used to treat DERMA. It contains Clobetasol (0.05% w/w) + Gentamicin (0.1% w/w), which Clobetasol: Anti-inflammatory via glucocorticoid receptor binding; Gentamicin: B. Always consult your doctor before use. Take as prescribed.
- Generic Name: Clobetasol + Gentamicin
- Manufacturer: Kaizen Research Labs India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ c-gen cream Uses & Benefits
Inflammatory dermatoses with secondary bacterial infection, e.g., eczema, psoriasis, contact dermatitis.
Off-label uses: Lichen planus, discoid lupus erythematosus.
๐ Drug Information
| Generic Name(s) | Clobetasol + Gentamicin |
| Brand Name | Cosvate-GM Cream |
| Manufacturer | Kaizen Research Labs India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Corticosteroid + Antibiotic |
| Route of Administration | Topical |
| Storage | Store at 20-25ยฐC; protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Clobetasol: Anti-inflammatory via glucocorticoid receptor binding; Gentamicin: Bactericidal by binding to 30S ribosomal subunit.
Mechanism Steps
๐ก How to Take c-gen cream
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of c-gen cream
โ Common Side Effects
- Burning
- itching
- irritation
- dryness
๐จ Serious Side Effects
- Adrenal suppression
- Cushing's syndrome
- Skin atrophy
- Secondary infection
โ ๏ธ Rare Side Effects
- Allergic contact dermatitis
- Hypopigmentation
- Perioral dermatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Aminoglycosides | Major | Increased nephrotoxicity and ototoxicity risk |
| Neuromuscular blocking agents | Major | Enhanced neuromuscular blockade |
| Loop diuretics | Moderate | Increased ototoxicity risk |
| Amphotericin B | Moderate | Increased nephrotoxicity risk |
| Other topical corticosteroids | Minor | Additive local effects |
๐จ Major Interactions
- Aminoglycosides
- Neuromuscular blocking agents
โก Moderate Interactions
- Loop diuretics
- Amphotericin B
โน๏ธ Minor Interactions
- Other topical corticosteroids
๐ฝ๏ธ Food Interactions
None known.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components, untreated bacterial/fungal/viral infections, skin ulcers, rosacea, perioral dermatitis.
๐ Monitoring Parameters
Skin condition, signs of infection, adrenal suppression with prolonged use.
๐คฑ Lactation Safety
Use with caution; avoid application to breast area.
๐ Overdose Management
Topical overdose unlikely; discontinue use and treat symptomatically.
โฐ Missed Dose
Apply as soon as remembered; skip if near next dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.