c knot 500mg/25mg/10mg tablet - Uses, Price, Side Effects & Substitutes
What is c knot 500mg/25mg/10mg tablet used for?
Anglocet Plus Tablet (Paracetamol + Phenylpropanolamine) is used to treat RESPIRATORY. It contains Paracetamol (500mg) + Phenylpropanolamine (25mg), which Paracetamol: Inhibits COX enzymes centrally, reducing prostaglandin synthesis. P. Always consult your doctor before use. Take as prescribed.
- Generic Name: Paracetamol + Phenylpropanolamine
- Manufacturer: Antigen Healthcare P. Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ c knot 500mg/25mg/10mg tablet Uses & Benefits
๐ Drug Information
| Generic Name(s) | Paracetamol + Phenylpropanolamine |
| Brand Name | Anglocet Plus Tablet |
| Manufacturer | Antigen Healthcare P. Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Analgesic, Antipyretic, Decongestant |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30ยฐC), protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Paracetamol: Inhibits COX enzymes centrally, reducing prostaglandin synthesis. Phenylpropanolamine: Alpha-1 adrenergic agonist causing vasoconstriction.
Mechanism Steps
๐ก How to Take c knot 500mg/25mg/10mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of c knot 500mg/25mg/10mg tablet
โ Common Side Effects
- Nausea
- Dizziness
- Insomnia
- Dry mouth
๐จ Serious Side Effects
- Hepatotoxicity
- Hypertension
- Arrhythmias
- Allergic reactions
โ ๏ธ Rare Side Effects
- Thrombocytopenia
- Agranulocytosis
- Cerebral hemorrhage
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Hypertensive crisis |
| Warfarin | Major | Increased INR and bleeding risk |
| Alcohol | Major | Increased hepatotoxicity |
| Antihypertensives | Moderate | Reduced antihypertensive effect |
| Beta-blockers | Moderate | Hypertensive episode |
| Tricyclic antidepressants | Moderate | Enhanced sympathomimetic effect |
| Caffeine | Minor | Additive stimulation |
| Oral contraceptives | Minor | Reduced paracetamol metabolism |
๐จ Major Interactions
- MAOIs
- Warfarin
- Alcohol (chronic use)
โก Moderate Interactions
- Antihypertensives
- Beta-blockers
- Tricyclic antidepressants
โน๏ธ Minor Interactions
- Caffeine
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Food may delay absorption of paracetamol.
๐ท Alcohol Interaction
Chronic alcohol use increases hepatotoxicity risk of paracetamol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hypertension, coronary artery disease, MAOI use, hyperthyroidism.
๐ Monitoring Parameters
Liver function, blood pressure, heart rate.
๐คฑ Lactation Safety
Paracetamol safe; Phenylpropanolamine excreted in milk, use caution.
๐ Overdose Management
Activated charcoal, N-acetylcysteine for paracetamol; supportive care for phenylpropanolamine.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose.