c hop aq 50mg injection - Progesterone (50mg) medicine

C Hop AQ 50mg Injection: Complete Medicine Guide

No reviews yet
🏭 Corona Remedies Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Progesterone is not assigned a pregnancy category by the FDA. It is used in pregnancy when medically indicated, such as for luteal support. Consult your doctor for individual risk assessment. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for primary uses.
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden shortness of breath or chest pain
  • Swelling or pain in one leg
  • Severe headache with visual changes
  • Yellowing of skin or eyes
  • Severe allergic reaction (rash, swelling of face or throat)
  • Unusual vaginal bleeding

If experiencing severe symptoms, call emergency services immediately.

What is c hop aq 50mg injection used for?

This medicine is a progesterone injection used to treat menstrual disorders and support pregnancy. It is given intramuscularly by a healthcare professional.

  • Generic Name: Progesterone (Natural Micronized)
  • Manufacturer: Corona Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 c hop aq 50mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा प्रोजेस्टेरोन हार्मोन की कमी से होने वाली समस्याओं के इलाज के लिए दी जाती है। इसका उपयोग मासिक धर्म न आने, असामान्य रक्तस्राव, और गर्भावस्था को सहारा देने के लिए किया जाता है। यह इंजेक्शन के रूप में मांसपेशी में दी जाती है और इसे डॉक्टर या नर्स द्वारा ही लगाया जाना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, सूजन, सिरदर्द, चक्कर आना, स्तनों में कोमलता, मतली और मासिक धर्म में बदलाव शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें खून के थक्के, गंभीर एलर्जी, और लीवर की समस्या हो सकती है। अगर आपको पैर में सूजन, सांस लेने में तकलीफ, या पीलिया हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा इंजेक्शन के रूप में दी जानी चाहिए। खुद से इंजेक्शन न लगाएं। अगर आपको खून के थक्के, लीवर की बीमारी, या किसी भी तरह की एलर्जी है तो डॉक्टर को बताएं। इस दवा के साथ शराब न पिएं। अपनी सभी दवाओं के बारे में डॉक्टर को जानकारी दें। समय पर फॉलो-अप करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 c hop aq 50mg injection Uses & Benefits

[{"condition":"Secondary amenorrhea","description":"Used to induce withdrawal bleeding in women with absent periods due to progesterone deficiency.","evidence":"Well-established"},{"condition":"Abnormal uterine bleeding","description":"Helps stabilize the endometrium and control abnormal bleeding in anovulatory cycles.","evidence":"Well-established"},{"condition":"Luteal phase support in assisted reproduction","description":"Supports the uterine lining after ovulation induction or embryo transfer.","evidence":"Well-established"},{"condition":"Threatened miscarriage","description":"May be used in women with luteal phase defect to support early pregnancy.","evidence":"Limited"},{"condition":"Hormone replacement therapy","description":"Used in combination with estrogen to protect the uterus in postmenopausal women.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Catamenial epilepsy","description":"Sometimes prescribed off-label to reduce seizure frequency related to menstrual cycle.","evidence":"Limited"},{"condition":"Premenstrual syndrome","description":"Occasionally used off-label for severe PMS symptoms.","evidence":"Limited"}]

Primary treatment for: Progesterone deficiency

Also treats: Secondary amenorrhea, Abnormal uterine bleeding, Luteal phase defect

📋 Drug Information

Generic Name(s)Progesterone (Natural Micronized)
Brand NameAqsusten 25 Solution for Injection
ManufacturerCorona Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassNatural Progesterone
Route of AdministrationIntramuscular injection only. Administer deep into a large muscle such as the gluteus maximus or deltoid. Rotate injection sites
StorageStore at room temperature (15-30°C). Protect from light. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine deep intramuscularly in the gluteal muscle to reduce injection site pain.
2
Rotate injection sites to prevent lipodystrophy.
3
Monitor patients for signs of thromboembolism, especially those with a history of blood clots.
4
Assess liver function periodically in patients with hepatic impairment.
5
Advise patients to avoid driving or operating machinery if they experience drowsiness.
6
Use with caution in patients with a history of depression and monitor mood changes.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Absent menstrual periods
This medicine is commonly prescribed for this.
Likely Use
✅
Abnormal uterine bleeding
This medicine helps control bleeding.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered intramuscularly and is absorbed rapidly from the injection site. The aqueous formulation allows for quick absorption compared to oil-based preparations.
DistributionProgesterone is highly lipophilic and distributes widely into body tissues, including the uterus, breasts, and brain. It also crosses the placenta and is excreted in breast milk.
Protein BindingApproximately 96-99% of progesterone is bound to plasma proteins, mainly albumin and corticosteroid-binding globulin.
MetabolismProgesterone is metabolized primarily in the liver by cytochrome P450 enzymes, including CYP3A4, to various metabolites such as pregnanediol and pregnanetriol.
Half-LifeThe elimination half-life of progesterone is approximately 5-20 minutes when given intravenously, but after intramuscular injection, the half-life is longer due to slow release from the injection site.
ExcretionProgesterone metabolites are excreted mainly in the urine as glucuronide and sulfate conjugates. A small amount is excreted in bile and feces.
BioavailabilityBioavailability after intramuscular injection is high, approaching 100%, but the exact value depends on the formulation and injection site.
Onset of ActionThe onset of action is within 1-2 hours after intramuscular injection.
Peak Plasma TimePeak plasma levels are reached within 1-4 hours after intramuscular injection.
Duration of ActionThe duration of action is approximately 24 hours, but this can vary depending on the clinical effect being monitored.

How It Works

This medicine works by binding to and activating progesterone receptors in the nucleus of target cells, particularly in the endometrium, myometrium, and mammary glands. This binding leads to changes in gene transcription that transform a proliferative endometrium into a secretory endometrium, which is necessary for implantation and maintenance of pregnancy. It also reduces uterine contractility and affects the cervical mucus. Additionally, it has mild anti-gonadotropic effects that can suppress ovulation at higher doses.

Mechanism Steps

1
Binding to progesterone receptor: This medicine diffuses into target cells and binds to the progesterone receptor in the cytoplasm, causing a conformational change.
2
Receptor translocation: The activated receptor moves into the nucleus and binds to specific DNA sequences called progesterone response elements.
3
Gene transcription: This binding alters the transcription of target genes, leading to the production of proteins that change cell function.
4
Endometrial changes: The endometrium becomes secretory, with increased glandular secretion and vascularity, preparing it for implantation.
5
Myometrial relaxation: Progesterone reduces the excitability of uterine smooth muscle, helping to maintain pregnancy.

💡 How to Take c hop aq 50mg injection

Strength: 50 mg per 1 mL aqueous injection

1This medicine is given by a healthcare professional as an intramuscular injection.
2You do not need to do anything to prepare for the injection.
3After the injection, you may be asked to stay for a short observation period.
4Follow your doctor's instructions for follow-up appointments.

Dosage Information

Adult DosageThe dose of this medicine is individualized by a qualified clinician based on the indication, patient's age, weight, and clinical response. For secondary amenorrhea, a typical regimen may be 50-100 mg intramuscularly once daily for 5-10 days. For luteal support, 25-50 mg daily may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustments are established for elderly patients. Use with caution and monitor for side effects.
Renal ImpairmentNo dose adjustment is established for renal impairment. Use with caution.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult a hepatologist.
Maximum Daily DoseThe maximum daily dose is not established from available information. Doses up to 100 mg daily have been used in clinical practice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
No specific timing required
This medicine is given by injection, so food does not affect its absorption.
Grapefruit
Avoid large amounts
May increase progesterone levels by inhibiting metabolism.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Contact your clinic to see if you should receive the missed dose.
💡 Do not self-administer.
📌 More than half the dosing interval has passed
→ Skip the missed dose and continue with your regular schedule.
💡 Do not double the dose.

⚠️ Side Effects of c hop aq 50mg injection

✅ Common Side Effects

Injection site pain (Common (10-20%))
Apply a cold pack to the area. It usually resolves within a day.
Headache (Common (5-10%))
Rest and stay hydrated. Consult your doctor if it persists.
Breast tenderness (Common (5-10%))
Wear a supportive bra. It usually improves with continued use.
Nausea (Common (5-10%))
Take with food if possible. If severe, contact your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel normal.

🚨 Serious Side Effects

Blood clots (deep vein thrombosis, pulmonary embolism) (Rare (<0.1%))
Seek immediate medical attention if you have leg swelling, chest pain, or shortness of breath.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience rash, itching, swelling of face or throat, or difficulty breathing.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Depression or mood changes (Uncommon (0.1-1%))
Contact your doctor if you feel persistently sad or have thoughts of self-harm.

⚠️ Rare Side Effects

Retinal thrombosis
Seek immediate ophthalmological care if you experience sudden vision loss.
Cholestatic jaundice
Report yellowing of skin or eyes to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Carbamazepine Major
Rifampicin Major
Ketoconazole Moderate
Fluconazole Moderate

🚨 Major Interactions

  • Warfarin
  • Carbamazepine
  • Rifampicin

⚡ Moderate Interactions

  • Ketoconazole
  • Fluconazole

🍷 Alcohol Interaction

Alcohol may increase the sedative effects of progesterone and could worsen dizziness. It is advisable to avoid alcohol while receiving this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to progesterone","History of or active thromboembolic disorders","Severe liver disease","Undiagnosed vaginal bleeding","Known or suspected breast cancer","Missed abortion"]

⚠️ Warnings & Precautions

["Use with caution in patients with a history of depression.","May cause fluid retention; caution in patients with cardiac or renal disease.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you have diabetes, as progesterone may affect blood sugar control.","Do not use for prevention of miscarriage unless prescribed for luteal phase deficiency."]

🤱 Lactation Safety

Progesterone is excreted in breast milk. Use with caution during breastfeeding, as it may affect milk production. Consult your doctor before use.

💊 Overdose Management

Overdose with progesterone is unlikely to cause serious effects. Symptoms may include nausea, vomiting, drowsiness, and dizziness. Treatment is supportive and symptomatic. Contact a poison control center if large amounts are ingested.

⏰ Missed Dose

If you miss a scheduled dose, contact your clinic or doctor for advice. Do not double the dose to catch up.

Additional Safety Advice

General Safety

This medicine must be given only by a qualified healthcare professional as an intramuscular injection. Do not attempt to self-administer. Inform your doctor if you have a history of blood clots, stroke, heart disease, liver disease, migraine, asthma, or epilepsy. Tell your doctor about all other medicines, especially anticoagulants, antifungals, and antibiotics, as they may interact. Avoid alcohol while receiving this medicine. Use effective contraception if you are not trying to conceive, as this medicine is not for birth control. If you miss a scheduled dose, contact your clinic for advice. Do not stop treatment without consulting your doctor. Regular monitoring may be needed for liver function and blood clotting. Keep all follow-up appointments.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and fluid retention. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. It may be prescribed to support early pregnancy in certain conditions. Do not use without medical supervision.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are receiving this medicine. It may affect blood clotting and interact with anesthetic agents. Your doctor will advise on whether to continue or temporarily stop it before surgery.

🦷 Dental Procedures

Inform your dentist that you are receiving this medicine. It may increase the risk of bleeding during dental procedures. Your dentist may take extra precautions.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce the risk of blood clots.
🥗
Stay physically active with regular low-impact exercise.
😴
Avoid smoking as it increases the risk of blood clots.
💧
Limit alcohol consumption.
🧘
Eat a balanced diet rich in fruits and vegetables.
🌞
Get adequate sleep to support hormonal balance.

🏋️ Exercise Considerations

Regular exercise is encouraged, but avoid strenuous activities that could increase the risk of blood clots. If you experience leg pain or swelling, stop exercising and consult your doctor.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce intake of processed and high-fat foods.
Stay well hydrated.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to schedule injections when you do not need to drive immediately after.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects such as blood clots or severe allergic reactions, seek immediate medical attention and your doctor will decide whether to stop treatment.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of blood clots, liver problems, and breast cancer. Regular monitoring of liver function and clinical assessment is recommended. Use the lowest effective dose for the shortest duration necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral progesterone

May be used as an alternative for some indications, but bioavailability is lower.

Evidence: Well-established
Vaginal progesterone

Often used for luteal support with fewer systemic side effects.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established. However, inform your doctor about this medicine before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label. Keep a copy of your prescription with you. Store at room temperature and protect from light. If traveling across time zones, consult your doctor about adjusting the timing of your doses. Declare the medicine at customs if required. Do not pack it in checked luggage; keep it in your carry-on bag.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with secondary amenorrhea
She had not had a period for 6 months. After evaluation, her doctor prescribed this medicine intramuscularly for 10 days. She experienced mild injection site pain but her periods resumed within a week after completing the course.
💡 Lesson: This medicine can effectively restore menstrual cycles in women with progesterone deficiency when used as prescribed.
👤 A 38-year-old woman undergoing IVF
She received this medicine for luteal phase support after embryo transfer. She reported breast tenderness and mild nausea but continued treatment as advised. She successfully conceived and delivered a healthy baby.
💡 Lesson: Luteal support with this medicine is crucial in assisted reproduction and side effects are manageable.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 1-2 hours after injection, but clinical effects such as withdrawal bleeding may take several days.

Q: Is this medicine safe during pregnancy?

A: It is used in pregnancy when prescribed by a doctor for specific indications. Consult your doctor for individual risk assessment.

Q: Can I take this medicine orally?

A: No, this medicine is for intramuscular injection only and must be given by a healthcare professional.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my fertility?
  • Can I drive after taking this medicine?
  • Does it interact with my other medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for c hop aq 50mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken orally.
    Fact: This medicine is for intramuscular injection only and must be given by a healthcare professional.
  • Myth: This medicine is a contraceptive.
    Fact: This medicine is not a contraceptive and should not be used for birth control.

🔄 Alternative Options

Generic Alternatives

  • Progesterone injection 50 mg

Brand Alternatives

  • C Hop AQ 50mg Injection

📊 Comparison with Similar Medicines

[{"medicine":"Progesterone injection","composition":"Progesterone 50 mg","route":"Intramuscular","uses":"Menstrual disorders, luteal support"},{"medicine":"Hydroxyprogesterone caproate injection","composition":"Hydroxyprogesterone caproate 250 mg","route":"Intramuscular","uses":"Prevention of preterm birth"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory