Butabrom 100 mg/4 mg/2.5 mg Tablet: Complete Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction (rash, swelling, difficulty breathing)
- Irregular or fast heartbeat
- Chest pain
- Worsening of breathing after taking the medicine
- Severe dizziness or fainting
- Muscle weakness or cramps (possible low potassium)
If experiencing severe symptoms, call emergency services immediately.
What is butabrom 100 mg/4 mg/2.5 mg tablet used for?
This medicine is a combination of salbutamol and etofylline used to treat bronchospasm in asthma and COPD. It works by relaxing the muscles in the airways to make breathing easier.
- Generic Name: Salbutamol + Etofylline
- Manufacturer: Rekvina Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 butabrom 100 mg/4 mg/2.5 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सल्ब्यूटामोल और एटोफिलिन का संयोजन है, जिसका उपयोग अस्थमा और सीओपीडी में श्वसन मार्ग की मांसपेशियों को आराम देकर सांस लेने में आसानी के लिए किया जाता है। यह घरघराहट, सांस की तकलीफ और छाती में जकड़न को कम करने में मदद करती है।
साइड इफेक्ट्स: सामान्य दुष्प्रभावों में कंपन, धड़कन, घबराहट, सिरदर्द और मांसपेशियों में ऐंठन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, अनियमित दिल की धड़कन और पोटेशियम की कमी हो सकती है।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। यदि आपको हृदय रोग, उच्च रक्तचाप, मधुमेह या थायरॉइड की समस्या है तो अपने डॉक्टर को बताएं। तीव्र अस्थमा के दौरे के लिए इसका उपयोग न करें; राहत के लिए इनहेलर का प्रयोग करें।
💊 butabrom 100 mg/4 mg/2.5 mg tablet Uses & Benefits
[{"condition":"Bronchial asthma","description":"Used to relieve bronchospasm and improve breathing in patients with asthma.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Helps to relax airways and reduce breathlessness in COPD patients.","evidence":"Well-established"},{"condition":"Bronchospasm associated with bronchitis","description":"May be used to relieve wheezing and chest tightness in bronchitis.","evidence":"Limited"}]
Off-label uses: []
Primary treatment for: Asthma
Also treats: COPD, Bronchitis
📋 Drug Information
| Generic Name(s) | Salbutamol + Etofylline |
| Brand Name | Albutamol Syrup |
| Manufacturer | Rekvina Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Bronchodilator (Beta-2 agonist + Xanthine derivative) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two bronchodilators with different mechanisms. Salbutamol selectively stimulates beta-2 adrenergic receptors in the airways, leading to relaxation of bronchial smooth muscle and rapid bronchodilation. Etofylline, a xanthine derivative, inhibits phosphodiesterase enzymes, increasing cyclic AMP levels and causing smooth muscle relaxation. Together, they work to open the airways and improve airflow.
Mechanism Steps
💡 How to Take butabrom 100 mg/4 mg/2.5 mg tablet
Strength: Each tablet contains salbutamol 100 mg and etofylline 4 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally two to three times daily, or as directed by your physician. The dose may be adjusted based on your condition and response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Use with caution and start with a lower dose as directed by a physician. |
| Renal Impairment | Dose adjustment may be needed in patients with renal impairment. Consult your doctor for personalized dosing. |
| Hepatic Impairment | Dose adjustment may be needed in patients with hepatic impairment. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum daily dose should not exceed the prescribed amount. Typically, not more than 3 tablets per day, but this must be confirmed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of butabrom 100 mg/4 mg/2.5 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Propranolol | Major | |
| MAOIs | Major | |
| Tricyclic antidepressants | Major | |
| Furosemide | Moderate | |
| Corticosteroids | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Non-selective beta-blockers (e.g., propranolol)
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
⚡ Moderate Interactions
- Diuretics (e.g., furosemide)
- Corticosteroids
- Digoxin
🍷 Alcohol Interaction
Alcohol may increase the risk of side effects such as dizziness, drowsiness, and palpitations. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to salbutamol, etofylline, or any component of the formulation","Severe cardiac disease (e.g., severe heart failure, arrhythmias)","Uncontrolled hypertension","Hyperthyroidism","Severe hepatic or renal impairment"]
⚠️ Warnings & Precautions
["Not for acute asthma attacks; use a short-acting bronchodilator inhaler for immediate relief.","May cause paradoxical bronchospasm; discontinue if breathing worsens.","Use with caution in patients with cardiovascular disorders, diabetes, hyperthyroidism, or seizure disorders.","May cause hypokalemia; monitor potassium levels, especially with concomitant diuretics or corticosteroids.","Avoid excessive caffeine intake as it may increase side effects.","Do not exceed the prescribed dose."]
🤱 Lactation Safety
Salbutamol is excreted in breast milk. It is generally considered safe during breastfeeding, but consult your doctor to weigh benefits and risks. Etofylline safety during lactation is not well established.
💊 Overdose Management
Overdose may cause severe tachycardia, tremor, palpitations, and hypokalemia. Seek immediate medical attention. Treatment is supportive and symptomatic. Monitor cardiac function and electrolytes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed. Do not exceed the recommended dose. Inform your doctor if you have heart disease, high blood pressure, diabetes, or thyroid problems. Avoid drinking alcohol while taking this medicine as it may increase side effects. Do not use this medicine to treat an acute asthma attack; use your rescue inhaler instead. Keep regular follow-up appointments to monitor your condition and adjust treatment if needed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to cardiovascular effects. Use with caution and monitor heart rate and blood pressure regularly.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy. This medicine should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist about this medicine before surgery. It may interact with anesthetic agents.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure. It may affect heart rate and blood pressure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you experience palpitations or dizziness. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause tremor or dizziness, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects, seek medical advice immediately.
📅 Long-Term Use Effects
Long-term use may lead to tolerance, increased heart rate, and electrolyte imbalances. Regular monitoring of heart function, potassium levels, and respiratory status is advised. Do not use for prolonged periods without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Inhalers deliver medicine directly to the lungs with fewer systemic side effects.
Evidence: Well-establishedAvoiding triggers and breathing exercises can complement medical treatment.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Keep enough supply for the entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 15-30 minutes after oral administration, with peak effects in 2-4 hours.
A: Consult your doctor first. It may not be suitable for uncontrolled hypertension.
A: Pediatric dosing is not established. Consult a pediatrician.
🤔 Common Patient Concerns
🔄 Substitutes for butabrom 100 mg/4 mg/2.5 mg tablet
View AllAlternative brands with exact same active ingredient:
-
azmino plus tabletMedoz Pharmaceutical Pvt. Ltd ₹12.90 40.3% CHEAPER
-
butabrom ds 100 mg/4 mg/2.5 mg tabletRekvina Laboratories Ltd ₹28.69 32.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for sudden asthma attacks.
Fact: This medicine is not for immediate relief. Use a fast-acting inhaler for acute attacks. - Myth: It is safe to take extra doses if symptoms worsen.
Fact: Taking more than prescribed can cause serious side effects. Always follow your doctor's advice.
🔄 Alternative Options
Generic Alternatives
- Salbutamol + Etofylline combination tablets from other manufacturers