Butabrom 100 mg/4 mg/2.5 mg Tablet - Uses, Price, Side Effects
What is butabrom 100 mg/4 mg/2.5 mg tablet used for?
Butabrom 100 mg/4 mg/2.5 mg Tablet is a combination medicine containing Salbutamol and Etofylline, used to treat respiratory conditions like asthma and COPD. It works by relaxing airway muscles and reducing inflammation, making breathing easier.
- Generic Name: Salbutamol + Etofylline
- Manufacturer: Rekvina Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ butabrom 100 mg/4 mg/2.5 mg tablet Uses & Benefits
Bronchial asthma, chronic obstructive pulmonary disease (COPD), reversible airway obstruction.
Off-label uses: Not well established; may be used in acute bronchospasm.
๐ Drug Information
| Generic Name(s) | Salbutamol + Etofylline |
| Brand Name | Albutamol Syrup |
| Manufacturer | Rekvina Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Bronchodilator (Beta-2 agonist + Xanthine derivative) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Salbutamol stimulates beta-2 adrenergic receptors, relaxing bronchial smooth muscle; Etofylline inhibits phosphodiesterase, increasing cAMP, and blocks adenosine receptors, leading to bronchodilation.
Mechanism Steps
๐ก How to Take butabrom 100 mg/4 mg/2.5 mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of butabrom 100 mg/4 mg/2.5 mg tablet
โ Common Side Effects
- Tremor
- Headache
- Tachycardia
- Palpitations
- Nausea
- Vomiting
- Insomnia
๐จ Serious Side Effects
- Arrhythmias
- Hypokalemia
- Seizures
- Paradoxical bronchospasm
- Chest pain
โ ๏ธ Rare Side Effects
- Allergic reactions
- Urticaria
- Angioedema
- Hyperglycemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Theophylline | Major | Increased risk of toxicity |
| Beta-blockers | Moderate | Reduced bronchodilator effect |
| Diuretics | Minor | Hypokalemia risk |
๐จ Major Interactions
- Beta-blockers
- MAOIs
- Tricyclic antidepressants
- Other xanthines
- Halogenated anesthetics
โก Moderate Interactions
- Diuretics
- Corticosteroids
- Sympathomimetics
- Digoxin
โน๏ธ Minor Interactions
- Antacids
- Caffeine
- Alcohol
๐ฝ๏ธ Food Interactions
High-fat meals may delay absorption; avoid excessive caffeine.
๐ท Alcohol Interaction
May increase risk of adverse effects (e.g., tachycardia).
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component, tachyarrhythmias, hypertrophic obstructive cardiomyopathy, uncontrolled hyperthyroidism.
๐ Monitoring Parameters
Heart rate, blood pressure, serum potassium, respiratory function, signs of tremor or palpitations.
๐คฑ Lactation Safety
Use with caution; both components excreted in breast milk.
๐ Overdose Management
Supportive care; monitor ECG, potassium; consider activated charcoal; beta-blockers for severe tachycardia (use cautiously).
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.