bultra 500mg injection

4.6 (14 reviews)

Tranexamic Acid (500mg)

🏭 Vostro Critical Care 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is bultra 500mg injection used for?

Armril Injection IP (Tranexamic Acid) is used to treat BLOOD RELATED. It contains Tranexamic Acid (500mg), which Competitively inhibits plasminogen activation and plasmin activity, thereby redu. Always consult your doctor before use. Take as prescribed.

Generic Name: Tranexamic Acid
Manufacturer: Vostro Critical Care
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 bultra 500mg injection Uses & Benefits

Menorrhagia, epistaxis, hemoptysis, gastrointestinal bleeding, hemophilia (adjunct), dental procedures in hemophiliacs, traumatic hyphema, hereditary angioedema.

Off-label uses: Cardiac surgery, orthopedic surgery, trauma, postpartum hemorrhage.

📋 Drug Information

Generic Name(s)	Tranexamic Acid
Brand Name	Armril Injection IP
Manufacturer	Vostro Critical Care
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	BLOOD RELATED
Action Class	Antifibrinolytic
Route of Administration	Intravenous (IV) injection or infusion.
Storage	Store at 20-25°C (68-77°F); protect from light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous administration results in complete bioavailability.

DistributionDistributes widely in body tissues and fluids; crosses placenta and blood-brain barrier.

Protein BindingApproximately 3% bound to plasma proteins.

MetabolismMinimal hepatic metabolism; primarily excreted unchanged.

Half-LifeApproximately 2-11 hours (mean 3.1 hours).

ExcretionPrimarily renal (over 90% unchanged in urine).

Bioavailability100% (intravenous).

Onset of ActionRapid (within minutes).

Peak Plasma TimeImmediately after IV administration.

Duration of ActionUp to 8 hours.

How It Works

Competitively inhibits plasminogen activation and plasmin activity, thereby reducing fibrinolysis and stabilizing clots.

Mechanism Steps

1Tranexamic acid binds to lysine binding sites on plasminogen and plasmin.

2This prevents plasminogen from binding to fibrin and being activated to plasmin.

3Plasmin activity is also directly inhibited.

💡 How to Take bultra 500mg injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of bultra 500mg injection

✅ Common Side Effects

Nausea
Vomiting
Diarrhea
Dizziness
Headache
Hypotension (with rapid IV injection)

🚨 Serious Side Effects

Thromboembolic events (DVT, PE, stroke)
Acute renal cortical necrosis
Seizures
Anaphylaxis
Visual disturbances

⚠️ Rare Side Effects

Color vision disturbances
Retinal artery occlusion
Hypersensitivity reactions

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased risk of thrombosis due to opposing mechanisms.
Heparin	Major	Increased risk of thrombosis.
Aspirin	Moderate	Additive antiplatelet effect may increase bleeding risk.
Oral Contraceptives	Moderate	Increased risk of thromboembolism.

🚨 Major Interactions

Warfarin
Heparin
Low molecular weight heparins
Direct oral anticoagulants (DOACs)
Thrombolytics (e.g., alteplase)

⚡ Moderate Interactions

Aspirin
NSAIDs
Clopidogrel
Antiplatelet agents
Estrogens
Oral contraceptives

ℹ️ Minor Interactions

Corticosteroids
Tetracyclines
Penicillins

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to tranexamic acid; active intravascular clotting; history of thromboembolic disease; subarachnoid hemorrhage; severe renal impairment.

📊 Monitoring Parameters

Renal function, signs of thrombosis, bleeding control.

🤱 Lactation Safety

Excreted in breast milk; use with caution.

💊 Overdose Management

No specific antidote; supportive care; consider hemodialysis if severe.

⏰ Missed Dose

Not applicable for single-dose or intermittent IV use; follow prescribed schedule.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for bultra 500mg injection

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Alternative brands with exact same active ingredient (Tranexamic Acid (500mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.