bulldose tz 200mg/600mg tablet
What is bulldose tz 200mg/600mg tablet used for?
Aflox TZ 200mg/600mg Tablet (Ofloxacin + Tinidazole) is used to treat GASTRO INTESTINAL. It contains Ofloxacin (200mg) + Tinidazole (600mg), which Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA rep. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ofloxacin + Tinidazole
- Manufacturer: Elysium Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bulldose tz 200mg/600mg tablet Uses & Benefits
Gastrointestinal infections (diarrhea, dysentery, giardiasis, amebiasis), intra-abdominal infections, mixed infections
Off-label uses: Helicobacter pylori eradication (in combination), pelvic inflammatory disease
๐ Drug Information
| Generic Name(s) | Ofloxacin + Tinidazole |
| Brand Name | Aflox TZ 200mg/600mg Tablet |
| Manufacturer | Elysium Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibiotic + Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication; Tinidazole enters cells and causes DNA damage via nitro radical formation
Mechanism Steps
๐ก How to Take bulldose tz 200mg/600mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bulldose tz 200mg/600mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Headache
- Dizziness
- Metallic taste
- Abdominal pain
๐จ Serious Side Effects
- Tendon rupture
- Peripheral neuropathy
- QT prolongation
- Seizures
- Clostridium difficile colitis
- Severe hypersensitivity reactions
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Hepatotoxicity
- Stevens-Johnson syndrome
- Anaphylaxis
- Pseudomembranous colitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Antidiabetic agents | Major | Hypoglycemia |
| QT prolonging drugs | Major | Increased risk of arrhythmias |
| NSAIDs | Major | Increased CNS stimulation and seizure risk |
| Theophylline | Moderate | Increased theophylline levels |
| Caffeine | Moderate | Reduced caffeine clearance |
| Cyclosporine | Moderate | Increased nephrotoxicity |
| Methotrexate | Moderate | Increased methotrexate toxicity |
| Antacids | Minor | Reduced absorption of ofloxacin |
| Sucralfate | Minor | Reduced absorption of ofloxacin |
| Iron supplements | Minor | Reduced absorption of ofloxacin |
| Zinc | Minor | Reduced absorption of ofloxacin |
๐จ Major Interactions
- Warfarin
- Antidiabetic agents
- QT prolonging drugs
- NSAIDs
โก Moderate Interactions
- Theophylline
- Caffeine
- Cyclosporine
- Methotrexate
โน๏ธ Minor Interactions
- Antacids
- Sucralfate
- Iron supplements
- Zinc
๐ฝ๏ธ Food Interactions
Avoid dairy products, calcium-fortified juices, and antacids within 2-4 hours; food delays absorption but does not affect extent
๐ท Alcohol Interaction
Avoid alcohol during and for 3 days after therapy due to disulfiram-like reaction with tinidazole
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to fluoroquinolones or nitroimidazoles, pregnancy, lactation, history of tendon disorders with quinolones, epilepsy, blood dyscrasias
๐ Monitoring Parameters
Renal function, hepatic function, blood glucose (in diabetics), ECG (if risk factors for QT prolongation), signs of tendonitis or neuropathy
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; no specific antidote; hemodialysis may remove tinidazole
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.