Brumed Syrup - Uses, Price, Side Effects, Composition
What is brumed syrup used for?
Brumed Syrup is a combination of Ibuprofen and Paracetamol used to relieve pain and reduce fever in children. Ibuprofen works by reducing hormones that cause inflammation and pain, while Paracetamol acts on the brain to lower fever. It is commonly used for headaches, toothaches, colds, and flu symptoms.
- Generic Name: Ibuprofen + Paracetamol
- Manufacturer: Health Care Formulations Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ brumed syrup Uses & Benefits
Mild to moderate pain, fever, inflammation (e.g., headache, dental pain, dysmenorrhea, osteoarthritis).
Off-label uses: Patent ductus arteriosus closure (ibuprofen), migraine (paracetamol).
๐ Drug Information
| Generic Name(s) | Ibuprofen + Paracetamol |
| Brand Name | Adiflam Plus 400 mg/500 mg Tablet |
| Manufacturer | Health Care Formulations Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Nonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ibuprofen inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in CNS, reducing pain and fever.
Mechanism Steps
๐ก How to Take brumed syrup
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of brumed syrup
โ Common Side Effects
- Nausea
- Dyspepsia
- Headache
- Dizziness
- Rash
๐จ Serious Side Effects
- GI bleeding
- Renal failure
- Hepatotoxicity
- Cardiovascular events
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Aplastic anemia
- Agranulocytosis
- Pancreatitis
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Moderate | Increased methotrexate toxicity |
| Aspirin | Moderate | Increased risk of gastrointestinal bleeding |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Lithium
- Aspirin
- Other NSAIDs
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- Corticosteroids
โน๏ธ Minor Interactions
- Antacids
- Caffeine
- Cholestyramine
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid high-fat meals.
๐ท Alcohol Interaction
Increased risk of GI bleeding and hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active GI bleeding, severe renal/hepatic impairment, third trimester pregnancy, history of asthma with NSAIDs.
๐ Monitoring Parameters
Renal function, hepatic function, blood pressure, signs of GI bleeding.
๐คฑ Lactation Safety
Ibuprofen: Safe in low doses; Paracetamol: Safe.
๐ Overdose Management
Activated charcoal, supportive care; for paracetamol overdose: N-acetylcysteine.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
This medicine was effective for me. I followed the doctor's advice.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.