broxet syrup - Terbutaline (1.25mg) + Ambroxol (30mg) medicine

Broxet Syrup: Complete Guide to Uses, Side Effects, and Safety

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🏭 Greenray Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Chest pain or palpitations
  • Severe dizziness or fainting
  • Difficulty breathing or worsening asthma
  • Swelling of face, lips, or throat
  • Severe skin rash or blistering
  • Muscle weakness or cramps
  • Irregular heartbeat

If experiencing severe symptoms, call emergency services immediately.

What is broxet syrup used for?

This medicine is a combination of terbutaline and ambroxol used to treat respiratory conditions like bronchitis and asthma. Terbutaline opens airways, while ambroxol thins mucus, making it easier to breathe and cough out phlegm.

  • Generic Name: Terbutaline (1.25mg) + Ambroxol (30mg)
  • Manufacturer: Greenray Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 broxet syrup के बारे में (Hindi Summary)

उपयोग: यह दवा टर्ब्यूटलाइन और एम्ब्रोक्सोल का संयोजन है, जिसका उपयोग ब्रोंकाइटिस, अस्थमा और अन्य श्वसन रोगों में किया जाता है। यह वायुमार्ग को खोलने और बलगम को पतला करने में मदद करती है, जिससे सांस लेना आसान हो जाता है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, सिरदर्द, चक्कर आना, हाथ-पैर कांपना और दिल की धड़कन तेज होना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सीने में दर्द, सांस लेने में कठिनाई, या चेहरे पर सूजन हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। दवा की मात्रा स्वयं न बढ़ाएं या घटाएं। यदि आपको हृदय रोग, उच्च रक्तचाप, मधुमेह, या थायरॉइड की समस्या है, तो डॉक्टर को बताएं। इस दवा को लेने के बाद चक्कर आ सकते हैं, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 broxet syrup Uses & Benefits

[{"condition":"Acute bronchitis","description":"Helps relieve bronchospasm and loosen mucus, making breathing easier and cough more productive.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Used to manage symptoms of chronic bronchitis by reducing bronchospasm and thinning mucus.","evidence":"Well-established"},{"condition":"Asthma","description":"Provides symptomatic relief of bronchospasm in asthma, but is not a substitute for controller medications.","evidence":"Established"},{"condition":"Productive cough","description":"Ambroxol helps thin and loosen mucus, making it easier to cough out.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Preterm labor management","description":"Terbutaline has been used off-label to delay preterm labor, but this use is not recommended due to safety concerns.","evidence":"Limited"}]

Primary treatment for: Bronchitis

Also treats: Asthma, Chronic obstructive pulmonary disease (COPD), Productive cough

📋 Drug Information

Generic Name(s)Terbutaline (1.25mg) + Ambroxol (30mg)
Brand Namebroxet syrup
ManufacturerGreenray Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not refrigerate. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this medicine after assessing the patient's cardiovascular status.
2
Advise patients to take the syrup with food to minimize gastric irritation.
3
Warn patients about the potential for dizziness and tremors; advise caution while driving.
4
Monitor potassium levels in patients on diuretics or corticosteroids.
5
Instruct patients not to exceed the recommended dose.
6
Advise patients to complete the full course as prescribed.
7
Use with caution in elderly patients and those with renal or hepatic impairment.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough
This medicine helps thin mucus and make cough more productive.
Likely Use
✅
Wheezing
Terbutaline helps relieve bronchospasm.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTerbutaline is well absorbed from the gastrointestinal tract after oral administration. Ambroxol is also rapidly absorbed from the gastrointestinal tract. However, oral bioavailability of terbutaline is reduced due to first-pass metabolism.
DistributionTerbutaline distributes widely into body tissues, including the lungs. Ambroxol distributes into lung tissue, bronchial secretions, and plasma. Both agents cross the placenta and are excreted in breast milk.
Protein BindingTerbutaline is approximately 25% bound to plasma proteins. Ambroxol is approximately 90% bound to plasma proteins.
MetabolismTerbutaline undergoes extensive first-pass metabolism in the liver, primarily by conjugation to sulfate and glucuronide metabolites. Ambroxol is metabolized in the liver by cytochrome P450 enzymes, mainly CYP3A4, to inactive metabolites.
Half-LifeThe elimination half-life of terbutaline is approximately 3 to 4 hours. The elimination half-life of ambroxol is approximately 7 to 12 hours.
ExcretionTerbutaline and its metabolites are primarily excreted in the urine. Ambroxol and its metabolites are mainly excreted in the urine, with a small amount in feces.
BioavailabilityThe oral bioavailability of terbutaline is approximately 15% due to first-pass metabolism. The oral bioavailability of ambroxol is approximately 70-80%.
Onset of ActionBronchodilation from terbutaline occurs within 30 minutes after oral administration. Ambroxol's mucolytic effect typically begins within 30-60 minutes.
Peak Plasma TimePeak plasma concentrations of terbutaline are reached within 2-4 hours after oral administration. Ambroxol reaches peak plasma levels within 1-3 hours.
Duration of ActionThe bronchodilator effect of terbutaline lasts approximately 4-6 hours. Ambroxol's mucolytic effect lasts approximately 6-8 hours.

How It Works

This medicine combines two active ingredients with complementary actions. Terbutaline is a selective beta-2 adrenergic agonist that binds to beta-2 receptors on bronchial smooth muscle, leading to relaxation and bronchodilation. Ambroxol is a mucolytic agent that reduces mucus viscosity by breaking down acidic mucopolysaccharide fibers and stimulating surfactant production, thereby facilitating mucus clearance. Together, they improve airflow and ease the removal of secretions.

Mechanism Steps

1
Terbutaline binds to beta-2 receptors: Terbutaline selectively binds to beta-2 adrenergic receptors on the surface of bronchial smooth muscle cells.
2
Activation of intracellular signaling: Binding triggers activation of adenylate cyclase, which increases cyclic AMP levels inside the cell.
3
Bronchial smooth muscle relaxation: Elevated cyclic AMP leads to relaxation of bronchial smooth muscle, resulting in bronchodilation and easier breathing.
4
Ambroxol reduces mucus viscosity: Ambroxol breaks down acidic mucopolysaccharide fibers in mucus, making it less thick and sticky.
5
Enhanced mucociliary clearance: Thinner mucus is more easily moved by cilia and coughed out, helping to clear airways.

💡 How to Take broxet syrup

Strength: Each 5 mL of syrup contains Terbutaline 1.25 mg and Ambroxol 30 mg.

1Shake the bottle well before each use.
2Use a measuring cup or spoon to measure the exact dose prescribed.
3Take the medicine with food to reduce stomach upset.
4Swallow the syrup slowly; do not mix with other liquids unless advised.
5After taking, close the bottle tightly and store as directed.
6Wash the measuring cup after each use.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 10 mL (2 teaspoons) taken two to three times a day, or as directed by your physician. The dose may be adjusted based on your condition and response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially cardiovascular effects. Use with caution and start with a lower dose as directed by a physician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 30 mL (6 teaspoons) in divided doses, or as prescribed by your doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of broxet syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel normal.
Tremor (Common (5-10%))
Usually decreases with continued use. Report to doctor if bothersome.
Palpitations (Uncommon (1-5%))
Report to your doctor if you experience a racing or pounding heartbeat.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face or throat, or difficulty breathing.
Chest pain or irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention if you experience chest pain, palpitations, or fainting.
Severe skin reactions (Rare (<0.1%))
Stop the medicine and seek immediate medical attention if you notice blistering, peeling, or rash.

⚠️ Rare Side Effects

Hypokalemia
Report muscle weakness or cramps to your doctor.
Hyperglycemia
Monitor blood sugar if diabetic and report changes to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Furosemide Moderate
Digoxin Moderate
Corticosteroids Moderate
Antacids Minor

🚨 Major Interactions

  • Beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Digoxin
  • Corticosteroids

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness caused by this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to terbutaline, ambroxol, or any component of the formulation","Severe cardiac disease, including arrhythmias and severe coronary insufficiency","Uncontrolled hypertension","Severe hepatic or renal impairment","Preterm labor (off-label use is contraindicated due to safety concerns)","Breastfeeding (unless benefits outweigh risks)"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular disorders, including coronary insufficiency, arrhythmias, and hypertension.","May cause hypokalemia; monitor potassium levels, especially in patients taking diuretics or corticosteroids.","May cause hyperglycemia; monitor blood glucose in diabetic patients.","May cause tremor and nervousness; advise patients to avoid driving if affected.","Not for use in acute severe asthma attacks; seek emergency care.","Use with caution in patients with seizure disorders.","Use with caution in patients with hyperthyroidism.","Safety and efficacy in children under 12 years not established."]

🤱 Lactation Safety

Terbutaline is excreted in breast milk and may cause adverse effects in the infant. Ambroxol is also excreted in breast milk. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose may cause severe tachycardia, palpitations, tremor, nausea, vomiting, and hypotension. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor cardiac and respiratory function.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without consulting your healthcare provider. Inform your doctor if you have a history of heart disease, high blood pressure, diabetes, thyroid problems, or seizures. This medicine may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you. Avoid alcohol while taking this medicine as it may increase drowsiness and other side effects. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of the reach of children. Do not use this medicine after the expiry date mentioned on the pack.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more susceptible to cardiovascular side effects. Use with caution and monitor heart rate and blood pressure regularly.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning pregnancy or are pregnant. This medicine should be used only if the potential benefit justifies the potential risk to the fetus.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, especially if you have heart or lung conditions.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with certain medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Stay well hydrated to help thin mucus.
😴
Use a humidifier to keep airways moist.
💧
Practice deep breathing exercises.
🧘
Avoid known allergens and pollutants.
🌞
Get adequate rest to support recovery.

🏋️ Exercise Considerations

Avoid strenuous exercise until your breathing improves. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Drink plenty of fluids.
Avoid cold and sugary drinks.
Include warm soups and broths.
Eat a balanced diet rich in vitamins and minerals.

💼 Impact on Daily Work & Life

This medicine may cause dizziness and tremors, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance to terbutaline's bronchodilator effects and increased risk of cardiovascular side effects. Regular monitoring of heart rate, blood pressure, and potassium levels is advised. Use for the shortest duration necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Can help loosen mucus and ease breathing.

Evidence: Traditional
Chest physiotherapy

Helps clear secretions from airways.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions reported. However, consult your doctor about flu and pneumonia vaccines if you have chronic respiratory disease.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old man with acute bronchitis
He was prescribed this medicine for a productive cough and wheezing. After taking it as directed with food, his cough became more productive and breathing improved within two days. He experienced mild nausea initially, which subsided after taking it with meals.
💡 Lesson: Taking this medicine with food reduces stomach upset and improves tolerability.
👤 A 60-year-old woman with chronic bronchitis
She used this medicine as part of her treatment plan. She noticed significant relief in chest congestion and was able to cough out mucus more easily. She was advised to monitor her heart rate due to a history of hypertension.
💡 Lesson: Regular monitoring and adherence to prescribed dose are key to safe and effective use.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 minutes after oral administration.

Q: Can I take it with other medicines?

A: Inform your doctor about all medicines you are taking, especially beta-blockers, MAOIs, and diuretics, as interactions may occur.

Q: Is it safe during pregnancy?

A: Consult your doctor before using this medicine during pregnancy. It should be used only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for broxet syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure asthma permanently.
    Fact: This medicine provides symptomatic relief but does not cure asthma. It should be used as part of a comprehensive treatment plan.
  • Myth: It is safe to take extra doses for faster relief.
    Fact: Taking more than the prescribed dose can lead to serious side effects. Always follow your doctor's instructions.

🔄 Alternative Options

Generic Alternatives

  • Terbutaline + Ambroxol syrup (various manufacturers)

Brand Alternatives

  • Broxet syrup

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Terbutaline 1.25 mg + Ambroxol 30 mg per 5 mL","onset":"30 minutes","duration":"4-6 hours"},{"medicine":"Salbutamol + Ambroxol","composition":"Salbutamol 2 mg + Ambroxol 30 mg per 5 mL","onset":"30 minutes","duration":"4-6 hours"}]

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