brophyle sr tablet - Acebrophylline (200mg) medicine

brophyle sr tablet - Uses, Price, Side Effects & Substitutes

No reviews yet
๐Ÿญ Zuventus Healthcare Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿคฐ Pregnancy Category C ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is brophyle sr tablet used for?

Ab Phylline (Acebrophylline) is used to treat RESPIRATORY. It contains Acebrophylline (200mg), which Inhibits phosphodiesterase and exhibits anti-inflammatory and bronchodilator eff. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Acebrophylline
  • Manufacturer: Zuventus Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š brophyle sr tablet Uses & Benefits

Bronchial asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis

Off-label uses: Apnea of prematurity, Post-extubation stridor

๐Ÿ“‹ Drug Information

Generic Name(s)Acebrophylline
Brand NameAb Phylline
ManufacturerZuventus Healthcare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassTheophylline & its derivatives
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration
DistributionWidely distributed in body tissues
Protein BindingApproximately 50-60%
MetabolismHepatic metabolism via CYP450 enzymes
Half-Life8-12 hours
ExcretionRenal excretion (primarily as metabolites)
BioavailabilityApproximately 70-80%
Onset of Action30-60 minutes
Peak Plasma Time2-4 hours
Duration of Action8-12 hours

How It Works

Inhibits phosphodiesterase and exhibits anti-inflammatory and bronchodilator effects

Mechanism Steps

1Inhibition of phosphodiesterase (PDE) enzymes, leading to increased intracellular cAMP and cGMP levels
2Relaxation of bronchial smooth muscle (bronchodilation)
3Anti-inflammatory effects via reduction of cytokine release and eosinophil activity

๐Ÿ’ก How to Take brophyle sr tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of brophyle sr tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Headache
  • Insomnia
  • Tremor
  • Palpitations

๐Ÿšจ Serious Side Effects

  • Seizures
  • Arrhythmias
  • Severe hypotension
  • Allergic reactions

โš ๏ธ Rare Side Effects

  • Rhabdomyolysis
  • Hyperglycemia
  • Hypokalemia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Theophylline Major Increased risk of theophylline toxicity
Cimetidine Major Reduced clearance of acebrophylline
Ciprofloxacin Major Increased acebrophylline levels
Erythromycin Major Increased acebrophylline levels
Fluvoxamine Major Reduced metabolism of acebrophylline
Lithium Moderate Increased lithium levels
Beta-blockers Moderate Antagonism of bronchodilator effect
Phenytoin Moderate Decreased acebrophylline levels
Rifampin Moderate Decreased acebrophylline levels
Caffeine Minor Additive stimulant effects
Alcohol Minor Increased gastrointestinal irritation
Smoking Minor Increased clearance of acebrophylline

๐Ÿšจ Major Interactions

  • Theophylline
  • Cimetidine
  • Ciprofloxacin
  • Erythromycin
  • Fluvoxamine

โšก Moderate Interactions

  • Lithium
  • Beta-blockers
  • Phenytoin
  • Rifampin

โ„น๏ธ Minor Interactions

  • Caffeine
  • Alcohol
  • Smoking

๐Ÿฝ๏ธ Food Interactions

High-fat meals may delay absorption; avoid excessive caffeine intake

๐Ÿท Alcohol Interaction

May increase risk of gastrointestinal irritation

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to acebrophylline or any component, acute myocardial infarction, hyperthyroidism, peptic ulcer

๐Ÿ“Š Monitoring Parameters

Lung function tests, serum drug levels (if co-administered with theophylline), heart rate, blood pressure

๐Ÿคฑ Lactation Safety

Use with caution; excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; induce vomiting or gastric lavage; monitor cardiac function

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip missed dose if close to next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for brophyle sr tablet

View All

Alternative brands with exact same active ingredient (Acebrophylline (200mg)):

Medical Note: Always consult your doctor before switching medications.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install