brivazen 50 tablet - Brivaracetam (50mg) medicine

brivazen 50 tablet

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🏭 Intas Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

What is brivazen 50 tablet used for?

This medicine contains Brivaracetam (50mg) and is used to treat NEURO CNS. High-affinity binding to synaptic vesicle protein 2A (SV2A), modulating neurotransmitter release.. Always consult your doctor before use.

  • Generic Name: Brivaracetam
  • Manufacturer: Intas Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 brivazen 50 tablet Uses & Benefits

Adjunctive therapy for partial-onset seizures in epilepsy.

Off-label uses: Generalized tonic-clonic seizures (limited data).

📋 Drug Information

Generic Name(s)Brivaracetam
Brand NameBrevipil 50 Tablet
ManufacturerIntas Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassSynaptic vescicle 2 A protein ligand (AED)
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly and completely absorbed after oral administration; bioavailability >90%.
DistributionVolume of distribution approximately 0.5 L/kg; crosses blood-brain barrier.
Protein Binding≤20% bound to plasma proteins.
MetabolismPrimarily metabolized by amide hydrolysis (not CYP-dependent) to inactive metabolite; minor CYP2C19 involvement.
Half-LifeApproximately 9 hours.
Excretion>95% excreted in urine (mainly as metabolites, <10% unchanged).
Bioavailability>90%.
Onset of ActionNot specified; rapid absorption suggests onset within hours.
Peak Plasma TimeApproximately 1 hour (fasted).
Duration of ActionApproximately 12 hours (twice-daily dosing).

How It Works

High-affinity binding to synaptic vesicle protein 2A (SV2A), modulating neurotransmitter release.

Mechanism Steps

1Binds to SV2A protein on synaptic vesicles
2Modulates vesicle exocytosis and neurotransmitter release
3Reduces excitatory neurotransmitter release (e.g., glutamate)
4Decreases neuronal hyperexcitability and seizure propagation

💡 How to Take brivazen 50 tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of brivazen 50 tablet

✅ Common Side Effects

Dizziness
Somnolence
Fatigue
Nausea
Vomiting

🚨 Serious Side Effects

Angioedema
Hypersensitivity reactions
Psychiatric symptoms (aggression, psychosis)

⚠️ Rare Side Effects

Pancreatitis
Hepatic failure
Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Carbamazepine Major Decreased brivaracetam exposure
Phenytoin Major Decreased brivaracetam exposure
Rifampin Major Decreased brivaracetam exposure
Lamotrigine Moderate Possible additive effects
Valproate Moderate Possible increased valproate levels
Oral contraceptives Moderate Reduced contraceptive efficacy
Cimetidine Minor Minimal interaction
Digoxin Minor Minimal interaction

🚨 Major Interactions

  • Carbamazepine
  • Phenytoin
  • Rifampin

⚡ Moderate Interactions

  • Lamotrigine
  • Valproate
  • Oral contraceptives

🍷 Alcohol Interaction

Avoid alcohol; may increase CNS depression.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to brivaracetam or any excipient.

🤱 Lactation Safety

Not recommended; excreted in breast milk.

💊 Overdose Management

Supportive care; no specific antidote; hemodialysis may remove drug.

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose.

🔄 Substitutes for brivazen 50 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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