brethnol syrup - Salbutamol (100mcg) medicine

Asthalin 100mcg Inhaler: Complete Guide to Uses, Side Effects, and Safety

No reviews yet
🏭 Bangalore Antibiotics & Biologicals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction with swelling of face, lips, or throat
  • Worsening of breathing immediately after using the inhaler
  • Chest pain or irregular heartbeat
  • Severe dizziness or fainting
  • Muscle weakness or cramps
  • High blood sugar levels in diabetic patients
  • Signs of low potassium such as palpitations or extreme fatigue

If experiencing severe symptoms, call emergency services immediately.

What is brethnol syrup used for?

This medicine is a rescue inhaler containing salbutamol, a short-acting beta-2 agonist that quickly opens the airways to relieve sudden breathing problems in asthma and other reversible airway diseases. It works within minutes and lasts for 4 to 6 hours.

  • Generic Name: Salbutamol
  • Manufacturer: Bangalore Antibiotics & Biologicals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 brethnol syrup के बारे में (Hindi Summary)

उपयोग: यह दवा सल्ब्यूटामोल नामक एक ब्रोन्कोडायलेटर है, जिसका उपयोग अस्थमा और अन्य श्वसन रोगों में सांस लेने में कठिनाई, घरघराहट और छाती में जकड़न से तुरंत राहत पाने के लिए किया जाता है। यह इनहेलर के रूप में उपयोग की जाती है और कुछ ही मिनटों में काम करना शुरू कर देती है। यह दवा व्यायाम के कारण होने वाली सांस की तकलीफ को रोकने के लिए भी इस्तेमाल की जा सकती है। यह दीर्घकालिक नियंत्रक दवाओं का विकल्प नहीं है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में हाथों में कंपन, सिरदर्द, घबराहट, तेज़ धड़कन और गले में जलन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, सांस लेने में अचानक कठिनाई, या दिल की धड़कन में अनियमितता हो सकती है। ऐसा होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग डॉक्टर के बताए अनुसार ही करें। बिना सलाह के खुराक न बढ़ाएं। यदि आपको यह इनहेलर सामान्य से अधिक बार लेना पड़ रहा है, तो डॉक्टर को बताएं। हर बार उपयोग से पहले इनहेलर को अच्छी तरह हिलाएं। उपयोग के बाद मुंह को पानी से धो लें। इसे हमेशा अपने पास रखें। धूम्रपान और धूल से बचें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 brethnol syrup Uses & Benefits

[{"condition":"Asthma","description":"Provides rapid relief from acute bronchospasm and is used as a rescue inhaler to treat sudden asthma attacks.","evidence":"Well-established"},{"condition":"Exercise-induced bronchospasm","description":"Used shortly before exercise to prevent narrowing of the airways triggered by physical activity.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"May be used to relieve reversible bronchospasm in some patients with COPD, though it is not a primary treatment.","evidence":"Established"},{"condition":"Other reversible obstructive airway diseases","description":"Can be used for acute relief of wheezing and shortness of breath in conditions where airway obstruction is reversible.","evidence":"Established"}]

Off-label uses: [{"condition":"Hyperkalemia","description":"Inhaled salbutamol is sometimes used in emergency settings to temporarily lower high blood potassium levels, but this is not a standard outpatient use.","evidence":"Limited"},{"condition":"Prevention of bronchospasm during anesthesia","description":"Occasionally used by anesthesiologists to prevent airway narrowing in patients with reactive airway disease during procedures.","evidence":"Limited"}]

Primary treatment for: Asthma

Also treats: Exercise-induced bronchospasm, Chronic obstructive pulmonary disease (COPD)

📋 Drug Information

Generic Name(s)Salbutamol
Brand NameAsthalin Syrup
ManufacturerBangalore Antibiotics & Biologicals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassShort acting β2-agonists
Route of AdministrationInhalation
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from direct sunlight and heat. Do not refrigerate. Keep the inhaler in its original packaging. Do not puncture or incinerate the canister. Keep away from children.
Shelf LifeThe shelf life is typically 24 months from the date of manufacture. Check the expiry date on the packaging. Do not use after the expiry date.
WHO GuidelineThe World Health Organization (WHO) recognizes salbutamol as an essential medicine for the treatment of asthma and other reversible obstructive airway diseases. It is included in the WHO Model List of Essential Medicines.
ICMR GuidelineThe Indian Council of Medical Research (ICMR) guidelines for asthma management recommend short-acting beta-2 agonists like salbutamol as first-line rescue therapy for acute asthma symptoms.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always carry your rescue inhaler with you, especially if you have asthma.
2
Use a spacer device if recommended by your doctor to improve delivery to the lungs.
3
Rinse your mouth after each use to prevent throat irritation.
4
Keep track of how often you use the inhaler; if you need it more than twice a week, consult your doctor.
5
Do not use the inhaler if the canister is damaged or past its expiry date.
6
Inform your doctor if you have heart problems, diabetes, or thyroid issues before using this medicine.
7
Shake the inhaler well before each use and follow proper technique.
8
Do not share your inhaler with others.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Wheezing
This medicine is commonly used to relieve wheezing due to bronchospasm.
Likely Use
Shortness of breath
This medicine provides rapid relief from shortness of breath in reversible airway diseases.
Likely Use
Chest tightness
This medicine helps relax airway muscles and relieve chest tightness.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Cough with phlegm
This medicine is not primarily used for cough with phlegm; consult a doctor.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAfter inhalation, salbutamol is rapidly absorbed from the lungs into the bloodstream. A portion of the dose is also swallowed and absorbed from the gastrointestinal tract, but this contributes less to the overall effect. The onset of action is within 5 minutes, and peak plasma levels are typically reached within 30 minutes after inhalation.
DistributionSalbutamol is widely distributed throughout the body, including the lungs and other tissues. It crosses the placenta and is excreted in breast milk in small amounts. The volume of distribution is approximately 156 liters in adults.
Protein BindingSalbutamol is approximately 10% bound to plasma proteins.
MetabolismSalbutamol is metabolized in the liver primarily by the enzyme sulfotransferase to an inactive sulfate conjugate. The swallowed portion of the inhaled dose undergoes extensive first-pass metabolism.
Half-LifeThe elimination half-life of salbutamol is approximately 4 to 6 hours.
ExcretionSalbutamol and its metabolites are excreted mainly in the urine, with a smaller amount eliminated in the feces. About 70% of an inhaled dose is excreted in the urine within 24 hours.
BioavailabilityThe bioavailability of salbutamol after inhalation is approximately 10% to 20% of the delivered dose, depending on the device and technique. The swallowed fraction has low oral bioavailability due to first-pass metabolism.
Onset of ActionThe onset of bronchodilation is within 5 minutes after inhalation.
Peak Plasma TimePeak plasma concentration is reached within 30 minutes after inhalation.
Duration of ActionThe bronchodilator effect lasts for approximately 4 to 6 hours.

How It Works

This medicine works by selectively stimulating beta-2 adrenergic receptors located on the smooth muscle cells of the airways. When salbutamol binds to these receptors, it activates an enzyme called adenylate cyclase, which increases the levels of cyclic adenosine monophosphate (cAMP) inside the cells. The rise in cAMP causes the smooth muscle to relax, leading to widening of the airways (bronchodilation). This effect occurs rapidly and helps to relieve wheezing and shortness of breath. At usual inhaled doses, salbutamol has relatively little effect on beta-1 receptors in the heart, but higher doses can stimulate the heart and cause a faster heart rate.

Mechanism Steps

1
Binding to beta-2 receptors: Salbutamol binds selectively to beta-2 adrenergic receptors on the surface of airway smooth muscle cells.
2
Activation of adenylate cyclase: This binding activates the enzyme adenylate cyclase inside the cell.
3
Increase in cyclic AMP: Activated adenylate cyclase raises the level of cyclic adenosine monophosphate (cAMP) in the cell.
4
Relaxation of smooth muscle: The increased cAMP causes the smooth muscle in the airways to relax, leading to bronchodilation.
5
Rapid relief of bronchospasm: The relaxed airways open up, making it easier to breathe and relieving symptoms of wheezing and chest tightness.

💡 How to Take brethnol syrup

Strength: Metered-dose inhaler delivering 100 micrograms of salbutamol per actuation.

1Remove the cap and check the mouthpiece for foreign objects.
2Shake the inhaler well for 5 seconds.
3Breathe out gently to empty your lungs.
4Place the mouthpiece in your mouth and close your lips around it.
5Press the canister down while breathing in slowly and deeply.
6Hold your breath for 10 seconds, then breathe out slowly.
7Wait 30 seconds before taking a second puff if prescribed.
8Rinse your mouth with water after use.
9Replace the cap and store the inhaler properly.

Dosage Information

Adult DosageThe usual adult dose for acute relief of bronchospasm is one to two inhalations (100 to 200 micrograms) as needed, up to a maximum of 4 to 8 inhalations in 24 hours. For prevention of exercise-induced bronchospasm, two inhalations (200 micrograms) are taken 15 to 30 minutes before exercise. The dose must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to treatment. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the cardiac effects of salbutamol. Use with caution and monitor heart rate and blood pressure. The dose should be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is typically required for mild to moderate renal impairment. In severe renal impairment, use with caution and monitor for adverse effects. Consult a clinician for individualized dosing.
Hepatic ImpairmentNo specific dose adjustment is typically required for mild to moderate hepatic impairment. In severe hepatic impairment, use with caution. Consult a clinician for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is generally 8 inhalations (800 micrograms) in 24 hours. However, this may vary based on medical advice. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Caffeine
Limit
May increase tremor and fast heartbeat.

⏰ What to Do If You Miss a Dose

📌 You are using the inhaler on a regular schedule and miss a dose
→ Take the missed dose as soon as you remember.
💡 If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
📌 You are using the inhaler as needed for symptoms
→ Use it when you have symptoms.
💡 Do not use more than the recommended dose.

⚠️ Side Effects of brethnol syrup

✅ Common Side Effects

Tremor (shaking of hands) (Common (5-10%))
This usually decreases with continued use. If it bothers you, consult your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if it persists.
Nervousness or restlessness (Common (5-10%))
Usually temporary. Avoid caffeine if it worsens.
Fast heartbeat (tachycardia) (Common (5-10%))
If it becomes bothersome or persistent, contact your doctor.
Throat irritation (Common (5-10%))
Rinse your mouth with water after each use.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience rash, swelling of face, lips, or throat, or difficulty breathing.
Paradoxical bronchospasm (Rare (<0.1%))
If breathing becomes worse immediately after using the inhaler, stop use and seek immediate medical attention.
Cardiac arrhythmias (irregular heartbeat) (Rare (<0.1%))
Seek medical attention if you feel palpitations, dizziness, or fainting.
Hypokalemia (low blood potassium) (Rare (<0.1%))
Report muscle weakness, cramps, or abnormal heart rhythms to your doctor.

⚠️ Rare Side Effects

Hyperglycemia (high blood sugar)
Monitor blood sugar if you have diabetes. Consult doctor if levels rise.
Lactic acidosis
Seek medical attention if you experience rapid breathing, confusion, or extreme fatigue.
Insomnia
Avoid taking close to bedtime if it affects sleep. Consult doctor if persistent.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
Furosemide Moderate
Digoxin Moderate
Theophylline Minor
Tricyclic antidepressants Major
MAO inhibitors Major
Corticosteroids Moderate
Diuretics Moderate
Levodopa Minor
Caffeine Minor

🚨 Major Interactions

  • Non-selective beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide, thiazides)
  • Digoxin
  • Corticosteroids (oral or inhaled)

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, or fast heartbeat when used with this medicine. It is advisable to limit or avoid alcohol while using this inhaler, especially if you experience side effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to salbutamol or any component of the inhaler","Severe cardiac disease or arrhythmias (relative contraindication)","Use with non-selective beta-blockers"]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose; excessive use can cause serious cardiac effects.","If you need this inhaler more frequently than usual, consult your doctor as it may indicate worsening asthma.","Use with caution in patients with cardiovascular disorders, hyperthyroidism, diabetes, or seizure disorders.","Paradoxical bronchospasm may occur; if it does, stop use and seek medical help.","Rinse mouth after use to prevent throat irritation.","Keep out of reach of children.","Do not puncture or incinerate the canister.","Store away from heat and direct sunlight."]

🤱 Lactation Safety

Salbutamol is excreted in breast milk in small amounts. It is generally considered safe for use during breastfeeding, but you should consult your doctor to weigh the benefits and risks. Monitor the baby for any unusual symptoms such as fast heartbeat or jitteriness.

💊 Overdose Management

Overdose with this inhaler can cause severe tachycardia, tremor, hypokalemia, hyperglycemia, and metabolic acidosis. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and may include monitoring of vital signs, electrolyte levels, and cardiac rhythm. Beta-blockers may be used cautiously to counteract cardiac effects, but they can cause bronchospasm in asthmatic patients.

⏰ Missed Dose

This medicine is used as needed for relief of acute symptoms. If you are using it on a regular schedule and miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up. If you are unsure, consult your doctor or pharmacist.

Additional Safety Advice

General Safety

Always use this medicine exactly as prescribed by your doctor. Do not increase the dose or frequency without medical advice, as using too much can lead to serious heart rhythm problems. If you find that you need this inhaler more often than usual, or if it stops working as well, tell your doctor promptly because this may mean your underlying condition is getting worse. Keep this inhaler with you at all times for emergencies. Before using, check the dose counter if available and shake the inhaler well. Rinse your mouth with water after each use to reduce the risk of throat irritation. Do not use this medicine if the canister is damaged or past its expiry date. Store it away from heat and direct sunlight. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not share your inhaler with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiac effects of this medicine. Use with caution and monitor heart rate and blood pressure. Consult a doctor for dose adjustments.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor. This medicine is generally considered safe during pregnancy when clinically needed, but your treatment plan may need to be reviewed.

🏥 Post-Surgery Considerations

Inform your anesthesiologist if you are using this inhaler, especially if you have asthma or reactive airway disease. It may be used during surgery to prevent bronchospasm.

🦷 Dental Procedures

Inform your dentist if you have asthma and use this inhaler. You may need to use it before dental procedures to prevent breathing problems.

💚 Lifestyle Tips for Better Results

🏃
Avoid known triggers such as dust, pollen, smoke, and cold air.
🥗
Maintain a healthy weight and engage in regular physical activity as tolerated.
😴
Practice breathing exercises to improve lung function.
💧
Keep your home clean and free from allergens.
🧘
Get adequate sleep and manage stress.
🌞
Stay hydrated to keep airways moist.

🏋️ Exercise Considerations

If you have exercise-induced asthma, use this inhaler 15 to 30 minutes before exercise. Warm up gradually and avoid exercising in cold, dry air. If symptoms occur during exercise, stop and use the inhaler as prescribed.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Include omega-3 fatty acids from fish or flaxseed.
Limit processed foods and added sugars.
Stay well hydrated.
Avoid foods that trigger allergies if you have known sensitivities.

💼 Impact on Daily Work & Life

This medicine may cause tremor or dizziness in some people. If affected, avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it should not interfere with your daily activities and can be used at work as needed.

🛑 When to Stop This Medicine

Do not stop using this medicine without consulting your doctor. If your asthma is well controlled and your doctor advises, they may adjust your treatment. If you experience serious side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine as a rescue inhaler is generally safe. However, frequent use may indicate poorly controlled asthma, which requires a review of your treatment plan. Overuse can lead to reduced effectiveness and increased risk of cardiac side effects. Regular follow-up with your doctor is important to monitor your condition and adjust therapy.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Levosalbutamol inhaler

Another short-acting beta-2 agonist that may be used as an alternative rescue inhaler.

Evidence: Well-established
Terbutaline inhaler

A similar rescue bronchodilator that can be used if salbutamol is not suitable.

Evidence: Well-established
Breathing exercises and physiotherapy

Can complement medicine to improve breathing control and reduce symptoms.

Evidence: Supportive

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions with this medicine. However, patients with asthma should follow their doctor's advice regarding influenza and pneumococcal vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not puncture or incinerate the canister

✅ DO

Keep away from direct sunlight and heat

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry your inhaler in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid extreme temperatures in checked baggage. If traveling across time zones, continue using as needed for symptoms. Check customs regulations for carrying prescription medicines. Store away from direct sunlight and heat.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 28-year-old woman with asthma
She experienced sudden wheezing and shortness of breath during a cold. She used her Asthalin inhaler as prescribed and felt relief within minutes. She learned to keep it with her at all times and to use a spacer for better effect.
💡 Lesson: Quick use of the rescue inhaler during an attack can prevent worsening of symptoms.
👤 A 45-year-old man with exercise-induced asthma
He used to avoid exercise due to breathing difficulty. His doctor advised him to use the inhaler 15 minutes before exercise. He now exercises regularly without symptoms.
💡 Lesson: Using the inhaler before exercise can prevent exercise-induced bronchospasm and improve quality of life.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 5 minutes after inhalation.

Q: How long does the effect last?

A: The effect lasts for approximately 4 to 6 hours.

Q: Can I use it for exercise-induced asthma?

A: Yes, it can be used 15 to 30 minutes before exercise to prevent symptoms.

Q: Is it safe during pregnancy?

A: It is generally considered safe when clinically needed, but consult your doctor.

Q: What should I do if I miss a dose?

A: If you are on a regular schedule, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this inhaler every day?
  • Will it affect my heart?
  • Can I use it during pregnancy?
  • Does it interact with my other medicines?
  • What if I miss a dose?
  • Can I drink alcohol while using this inhaler?

🔄 Substitutes for brethnol syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This inhaler is addictive.
    Fact: This medicine is not addictive. It is a rescue medicine that helps relieve breathing problems and does not cause dependence.
  • Myth: Using this inhaler regularly will make it stop working.
    Fact: Using this inhaler as prescribed for rescue relief does not make it stop working. However, if you need it more often, it may mean your asthma is not well controlled, and you should consult your doctor.
  • Myth: This inhaler can replace my controller medicine.
    Fact: This inhaler is a rescue medicine and does not replace controller medicines that reduce airway inflammation. Both may be needed for effective asthma management.

🔄 Alternative Options

Generic Alternatives

  • Salbutamol 100 mcg inhaler

Brand Alternatives

  • Asthalin 100 mcg inhaler
  • Ventorlin 100 mcg inhaler
  • Salbair 100 mcg inhaler

📊 Comparison with Similar Medicines

[{"medicine":"Salbutamol","class":"Short-acting beta-2 agonist","onset":"5 minutes","duration":"4-6 hours","use":"Rescue"},{"medicine":"Levosalbutamol","class":"Short-acting beta-2 agonist","onset":"5 minutes","duration":"4-6 hours","use":"Rescue"},{"medicine":"Formoterol","class":"Long-acting beta-2 agonist","onset":"10-15 minutes","duration":"12 hours","use":"Controller and rescue"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory