bp 1200000iu injection

4.5 (4 reviews)

Penicillin G (1200000IU)

🏭 Karnataka Antibiotics & Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is bp 1200000iu injection used for?

Benzylpenicillin 1000000IU Injection (Penicillin G) is used to treat ANTI INFECTIVES. It contains Penicillin G (1200000IU), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.

Generic Name: Penicillin G
Manufacturer: Karnataka Antibiotics & Pharmaceuticals Ltd
Form: Allopathy
Pregnancy Category: B
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 bp 1200000iu injection Uses & Benefits

Treatment of infections caused by susceptible organisms including streptococcal infections, pneumococcal infections, meningococcal meningitis, syphilis, and actinomycosis.

Off-label uses: Lyme disease, Anthrax prophylaxis

📋 Drug Information

Generic Name(s)	Penicillin G
Brand Name	Benzylpenicillin 1000000IU Injection
Manufacturer	Karnataka Antibiotics & Pharmaceuticals Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI INFECTIVES
Action Class	Cell wall active agent - Narrow spectrum Penicillin
Route of Administration	Intramuscular or intravenous injection.
Storage	Store at 20-25°C (68-77°F); protect from moisture. Reconstituted solution should be used immediately or refrigerated and used within 24 hours.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after intramuscular injection; peak serum concentrations achieved within 15-30 minutes.

DistributionWidely distributed throughout body tissues and fluids; penetrates into cerebrospinal fluid only when meninges are inflamed.

Protein BindingApproximately 60% bound to serum albumin.

MetabolismMinimally metabolized in the liver; primarily excreted unchanged.

Half-Life30-60 minutes in patients with normal renal function.

ExcretionRenal excretion via glomerular filtration and tubular secretion; about 60-90% excreted unchanged in urine.

BioavailabilityNot applicable for injection; intramuscular administration yields complete bioavailability.

Onset of ActionRapid; within 15-30 minutes after intramuscular injection.

Peak Plasma Time15-30 minutes after intramuscular injection.

Duration of Action4-6 hours.

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase activity, and activating autolytic enzymes.

Mechanism Steps

1Penicillin G binds to penicillin-binding proteins (PBPs) located on the bacterial cell wall.

2Inhibition of transpeptidase enzyme prevents cross-linking of peptidoglycan chains.

3Disruption of cell wall synthesis leads to activation of autolytic enzymes.

💡 How to Take bp 1200000iu injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of bp 1200000iu injection

✅ Common Side Effects

Diarrhea
Nausea
Vomiting
Injection site pain
Rash

🚨 Serious Side Effects

Anaphylaxis
Severe hypersensitivity reactions
Clostridium difficile colitis
Seizures (with high doses)

⚠️ Rare Side Effects

Interstitial nephritis
Hemolytic anemia
Leukopenia
Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Methotrexate	Major	Increased methotrexate toxicity
Probenecid	Major	Decreased renal excretion of penicillin, increased penicillin levels
Oral contraceptives	Moderate	Reduced contraceptive efficacy
Aminoglycosides	Moderate	Synergistic bactericidal effect; potential for increased nephrotoxicity
Cyclosporine	Moderate	Possible decreased cyclosporine levels
Tetracyclines	Minor	Antagonistic effect
Chloramphenicol	Minor	Antagonistic effect

🚨 Major Interactions

Warfarin
Methotrexate
Probenecid

⚡ Moderate Interactions

Oral contraceptives
Aminoglycosides
Cyclosporine

ℹ️ Minor Interactions

Tetracyclines
Chloramphenicol

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to penicillins or any component of the formulation.

📊 Monitoring Parameters

Renal function, signs of hypersensitivity, and therapeutic response.

🤱 Lactation Safety

Excreted in breast milk in low concentrations; generally considered compatible with breastfeeding.

💊 Overdose Management

Supportive care; hemodialysis may be considered in severe cases.

⏰ Missed Dose

Administer as soon as possible; if close to next dose, skip missed dose and resume regular schedule. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for bp 1200000iu injection

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Alternative brands with exact same active ingredient (Penicillin G (1200000IU)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026