benzathine 500000iu injection
What is benzathine 500000iu injection used for?
Benzathine 1200000IU Injection (Benzathine penicillin G) is used to treat ANTI INFECTIVES. It contains Benzathine penicillin G (500000IU), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.
- Generic Name: Benzathine penicillin G
- Manufacturer: Karnataka Antibiotics & Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ benzathine 500000iu injection Uses & Benefits
Syphilis (primary, secondary, latent, tertiary), rheumatic fever prophylaxis, streptococcal infections
Off-label uses: Yaws, pinta, bejel, leptospirosis
๐ Drug Information
| Generic Name(s) | Benzathine penicillin G |
| Brand Name | Benzathine 1200000IU Injection |
| Manufacturer | Karnataka Antibiotics & Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cell wall active agent - Narrow spectrum Penicillin |
| Route of Administration | Intramuscular (deep IM) |
| Storage | Store at 2-8ยฐC; do not freeze |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs)
Mechanism Steps
๐ก How to Take benzathine 500000iu injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of benzathine 500000iu injection
โ Common Side Effects
- Pain at injection site
- Nausea
- Diarrhea
- Rash
๐จ Serious Side Effects
- Anaphylaxis
- Stevens-Johnson syndrome
- Hemolytic anemia
- Interstitial nephritis
โ ๏ธ Rare Side Effects
- Pseudomembranous colitis
- Seizures (high doses)
- Jarisch-Herxheimer reaction
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Methotrexate | Major | Increased methotrexate toxicity |
| Warfarin | Major | Increased bleeding risk |
| Oral typhoid vaccine | Major | Reduced vaccine efficacy |
| Probenecid | Moderate | Increased penicillin levels |
| Heparin | Moderate | Increased risk of bleeding |
| Live bacterial vaccines | Moderate | Reduced vaccine efficacy |
| Oral contraceptives | Minor | Reduced contraceptive efficacy |
| Disulfiram | Minor | Possible disulfiram-like reaction |
๐จ Major Interactions
- Methotrexate
- Warfarin
- Oral typhoid vaccine
โก Moderate Interactions
- Probenecid
- Heparin
- Live bacterial vaccines
โน๏ธ Minor Interactions
- Oral contraceptives
- Disulfiram
๐ฝ๏ธ Food Interactions
None known
๐ท Alcohol Interaction
No significant interaction
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to penicillins, cephalosporins, or any component
๐ Monitoring Parameters
Renal function, CBC, signs of hypersensitivity
๐คฑ Lactation Safety
Safe; excreted in low amounts
๐ Overdose Management
Supportive care; hemodialysis may remove drug
โฐ Missed Dose
Administer as soon as possible; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.
Found this to be a helpful product. Good results.