Liofen 5 Tablet (Baclofen 5mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Extreme sleepiness or difficulty staying awake
- Slow, shallow, or irregular breathing
- Hallucinations or severe confusion
- Seizures or convulsions
- Rapid heartbeat with fever and muscle rigidity after missing doses
- Severe allergic reaction with swelling of face, lips, or throat
- Yellowing of skin or eyes or dark urine
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is bolofen 5mg tablet used for?
This medicine contains Baclofen 5 mg, a muscle relaxant used to treat muscle spasticity caused by conditions like multiple sclerosis, spinal cord injury, or cerebral palsy. It works by calming nerve signals in the spinal cord and brain, reducing muscle tightness and spasms. It is a prescription medicine and must be taken exactly as directed by your doctor.
- Generic Name: Baclofen (5mg)
- Manufacturer: Crescent Therapeutics Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 bolofen 5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा बैक्लोफेन 5 मिलीग्राम की एक गोली है जिसका उपयोग मांसपेशियों की अकड़न और ऐंठन को कम करने के लिए किया जाता है। यह मुख्य रूप से मल्टीपल स्क्लेरोसिस, रीढ़ की हड्डी की चोट, सेरेब्रल पाल्सी और अन्य न्यूरोलॉजिकल समस्याओं में होने वाली मांसपेशियों की अत्यधिक कठोरता के इलाज के लिए दी जाती है। यह दवा दिमाग और रीढ़ की हड्डी में तंत्रिकाओं के संकेतों को शांत करके मांसपेशियों को ढीला करने में मदद करती है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और डॉक्टर की सलाह के बिना इसे अचानक बंद नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, कमजोरी, थकान और जी मिचलाना शामिल हैं। ये आमतौर पर हल्के होते हैं और शरीर के सामान्य होने पर कम हो जाते हैं। कुछ लोगों को सिरदर्द, भ्रम या चलने में अस्थिरता महसूस हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अत्यधिक नींद, सांस लेने में कठिनाई, या दवा अचानक बंद करने पर मतिभ्रम जैसी समस्याएं हो सकती हैं। अगर कोई भी दुष्प्रभाव परेशान करे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से दवा की मात्रा न बढ़ाएं, न घटाएं और न ही अचानक बंद करें, क्योंकि इससे गंभीर लक्षण हो सकते हैं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या भारी मशीनरी चलाने से बचें। इस दवा के साथ शराब बिल्कुल न पिएं। अगर आपको किडनी या लीवर की बीमारी है तो डॉक्टर को जरूर बताएं। दवा को मूल डिब्बे में, ठंडी और सूखी जगह पर, बच्चों की पहुंच से दूर रखें।
💊 bolofen 5mg tablet Uses & Benefits
[{"condition":"Muscle spasticity in multiple sclerosis","description":"This medicine helps reduce the stiffness and involuntary muscle contractions that are common in multiple sclerosis, improving comfort and mobility.","evidence":"Well-established"},{"condition":"Muscle spasticity in spinal cord injury","description":"It is used to relieve severe muscle tightness and spasms caused by spinal cord damage, helping patients with positioning and daily care.","evidence":"Well-established"},{"condition":"Muscle spasticity in cerebral palsy","description":"In selected patients, this medicine may be prescribed to reduce spasticity associated with cerebral palsy, often as part of a broader rehabilitation plan.","evidence":"Moderate"},{"condition":"Muscle spasms of neurological origin","description":"It can help control painful muscle spasms that arise from various neurological disorders when other measures are not enough.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Alcohol use disorder","description":"Some specialists prescribe Baclofen off-label to reduce alcohol cravings and consumption, but this use remains controversial and requires close medical supervision.","evidence":"Limited"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"Baclofen has been studied off-label to reduce reflux episodes by relaxing the lower esophageal sphincter, but it is not a standard treatment.","evidence":"Limited"},{"condition":"Trigeminal neuralgia","description":"Rarely, Baclofen may be tried off-label for certain types of facial pain, usually when standard treatments fail.","evidence":"Limited"}]
Primary treatment for: Muscle spasticity
Also treats: Multiple sclerosis, Spinal cord injury, Cerebral palsy, Neurological muscle spasms
📋 Drug Information
| Generic Name(s) | Baclofen (5mg) |
| Brand Name | bolofen 5mg tablet |
| Manufacturer | Crescent Therapeutics Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Skeletal muscle relaxant- Centrally acting |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in their original container, tightly closed, away from moisture and direct sunlight. Do not store in the bathroom. |
| Shelf Life | Typically 24 months from the date of manufacture, but always check the expiry date printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by mimicking the action of gamma-aminobutyric acid (GABA), which is a natural chemical in the brain and spinal cord that calms nerve activity. Baclofen binds to GABA-B receptors in the spinal cord and brain, which reduces the release of excitatory neurotransmitters that would otherwise keep muscles overly tight. By dampening these signals, it helps restore a more normal balance between muscle contraction and relaxation. This effect is most helpful in conditions where spasticity originates from the central nervous system rather than from the muscle itself.
Mechanism Steps
💡 How to Take bolofen 5mg tablet
Strength: Immediate-release tablet, 5 mg
Dosage Information
| Adult Dosage | The starting dose of this medicine for adults is usually 5 mg taken two or three times a day. Your doctor will gradually increase the dose based on your response and tolerance, often up to a maximum of 80 mg per day in divided doses for spasticity. For other conditions, the dose may be different. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never adjust the dose without your doctor's guidance. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients are more sensitive to the sedative effects of this medicine and are at higher risk of confusion and falls. Treatment should be started at the lowest possible dose and increased slowly. Kidney function should be checked before and during treatment, as reduced kidney function is common in older adults and can lead to drug accumulation. |
| Renal Impairment | In patients with impaired kidney function, the dose of this medicine must be reduced. For mild to moderate impairment, a lower starting dose and slower titration are recommended. In severe kidney impairment, the medicine should be used with extreme caution or avoided, as it can accumulate and cause serious side effects. Close monitoring is essential. |
| Hepatic Impairment | Mild to moderate liver impairment usually does not require dose adjustment, as Baclofen is primarily eliminated unchanged by the kidneys. However, in severe liver disease, caution is advised and monitoring for side effects is recommended. |
| Maximum Daily Dose | The maximum recommended daily dose for spasticity is 80 mg per day in divided doses, but this may vary depending on the condition and the patient's response. Doses above 80 mg per day are not recommended in routine practice. Always follow your doctor's prescription. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of bolofen 5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Opioid painkillers | Major | |
| Benzodiazepines | Major | |
| Tricyclic antidepressants | Major | |
| MAO inhibitors | Major | |
| Antihypertensives | Moderate | |
| Lithium | Moderate | |
| NSAIDs | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- Other central nervous system depressants (e.g., opioids, benzodiazepines, alcohol)
- Tricyclic antidepressants (e.g., amitriptyline)
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- Antihypertensive medicines
- Lithium
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
🍷 Alcohol Interaction
Alcohol should be strictly avoided while taking this medicine. Both alcohol and Baclofen depress the central nervous system, and combining them can lead to excessive sedation, dizziness, impaired coordination, and dangerously slow breathing. If you drink alcohol regularly, discuss this with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to Baclofen or any component of the tablet","Porphyria (a rare blood disorder)","Severe kidney impairment (dose adjustment or avoidance may be needed)","Epilepsy or a history of seizures (use with caution and only under specialist supervision)","Abrupt discontinuation of therapy (must be tapered gradually)"]
⚠️ Warnings & Precautions
["Do not stop this medicine suddenly, as it can cause withdrawal symptoms including hallucinations, seizures, and rapid heartbeat.","Use with caution in elderly patients, who are more sensitive to sedation and confusion.","Avoid driving or operating heavy machinery until you know how this medicine affects you.","Inform your doctor if you have kidney or liver disease, as dose adjustments may be necessary.","Do not drink alcohol while taking this medicine.","Use with caution in people with a history of psychiatric disorders, as it can worsen confusion or hallucinations.","Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Baclofen is excreted in breast milk in small amounts. Most experts consider it compatible with breastfeeding, but you should monitor your baby for drowsiness or poor feeding. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose of this medicine can cause severe drowsiness, confusion, hallucinations, slow or irregular breathing, and loss of consciousness. If you suspect an overdose, seek emergency medical care immediately. Treatment is supportive and may include monitoring of breathing, heart rate, and blood pressure. In severe cases, hospitalization and mechanical ventilation may be required. There is no specific antidote, but activated charcoal may be used if the overdose is recent and the patient is alert.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you miss several doses in a row, contact your doctor before restarting, as abrupt discontinuation can cause withdrawal symptoms.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not increase, decrease, or stop the dose on your own, because sudden withdrawal can cause serious reactions such as hallucinations, seizures, or a rapid heartbeat. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness and dizziness. Do not drink alcohol while taking this medicine, as it can increase sedation and impair your coordination. Inform your doctor if you have kidney disease, liver disease, or a history of seizures, as the dose may need adjustment. Keep all follow-up appointments so your doctor can monitor your response and adjust the dose safely. Store this medicine in its original container, away from moisture and direct sunlight, and keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and dizzying effects of this medicine. They are also more likely to have reduced kidney function, which can lead to drug accumulation. Treatment should be started at the lowest possible dose and increased slowly. Regular monitoring of kidney function, blood pressure, and mental status is recommended. Falls are a particular risk, so precautions should be taken.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss this with your doctor before conception. The safety of this medicine during pregnancy is not fully established, and it should only be used if clearly needed. Your doctor may adjust your treatment plan or switch to an alternative medicine. Do not stop this medicine on your own if you become pregnant; seek medical advice immediately.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It can interact with anesthetic agents and other medicines used during surgery, increasing the risk of sedation and respiratory depression. Your doctor may advise you to temporarily adjust or stop the medicine before surgery, but never do so without medical guidance.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It can interact with sedatives or anesthetics used in dentistry, increasing drowsiness. Your dentist may need to adjust the medications used or take extra precautions. Do not stop this medicine before a dental visit unless your doctor advises it.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness, dizziness, and muscle weakness, which may affect your balance and coordination. Avoid high-impact or risky exercises until you know how the medicine affects you. Always warm up before exercise and cool down afterward. If you feel dizzy or weak during exercise, stop immediately and rest. Consult your physiotherapist or doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to drive, operate machinery, or perform tasks that require alertness. You should avoid these activities until you know how the medicine affects you. If your job involves operating heavy equipment or driving, discuss with your doctor about adjusting your dose or timing. Most people can continue their usual work activities with appropriate precautions.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor will decide when and how to stop it, usually by gradually reducing the dose over days to weeks. If you experience side effects that are intolerable, contact your doctor before making any changes. Abrupt discontinuation can cause withdrawal symptoms such as hallucinations, seizures, and rapid heartbeat.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored appropriately. However, tolerance can develop, requiring dose adjustments. Regular monitoring of kidney function, muscle tone, and sedation levels is important. Some patients may experience persistent drowsiness or weakness. Abrupt discontinuation after long-term use can cause severe withdrawal symptoms, so tapering is essential. Periodic review with your doctor is recommended to ensure the dose remains optimal and to assess whether continued treatment is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Stretching, strengthening, and range-of-motion exercises can complement medicine and help manage spasticity.
Evidence: Well-establishedFor focal spasticity, injections can provide targeted relief without systemic side effects.
Evidence: Well-establishedHelps adapt daily activities and improve function despite spasticity.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive routine vaccinations while taking this medicine, but always inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your hand luggage to avoid loss or exposure to extreme temperatures. If you are crossing time zones, consult your doctor about how to adjust your dosing schedule. Store the tablets at room temperature and avoid leaving them in a hot car or checked luggage. Check the customs regulations of your destination country regarding prescription medicines, and carry a doctor's letter if you are carrying more than a personal supply.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice some effect within 30 minutes to 1 hour after a dose, but the full benefit for spasticity usually takes several days to weeks of regular dosing.
A: No, you must never stop this medicine suddenly. Your doctor will give you a tapering schedule to avoid serious withdrawal symptoms.
A: No, alcohol should be completely avoided as it increases sedation and the risk of dangerous respiratory depression.
A: If you remember within half the dosing interval, take the missed dose. Otherwise, skip it and continue with your regular schedule. Do not double dose.
A: Limited data are available. It should only be used during pregnancy if your doctor decides the benefits outweigh the risks.
🤔 Common Patient Concerns
🔄 Substitutes for bolofen 5mg tablet
View AllAlternative brands with exact same active ingredient:
-
eptil 5mg tabletCrescent Therapeutics Ltd ₹49.52 10% CHEAPER
-
baclofast 5mg tabletWalnut Lifesciences ₹54.00 1.8% CHEAPER
-
back 5mg tabletEast West Pharma ₹54.60 0.7% CHEAPER
-
bacfen 5 tabletIcon Life Sciences ₹67.50 22.7% COSTLIER
-
liofen 5 tabletSun Pharmaceutical Industries Ltd ₹67.94 23.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a painkiller for everyday aches and pains.
Fact: This medicine is a muscle relaxant specifically for spasticity of neurological origin. It is not a general painkiller and should not be used for ordinary muscle soreness. - Myth: You can stop this medicine whenever you feel better.
Fact: Stopping this medicine suddenly can cause dangerous withdrawal symptoms. It must be tapered gradually under medical supervision. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol greatly increases the sedative effects of this medicine and can lead to dangerous respiratory depression. It should be avoided completely. - Myth: This medicine works immediately after the first dose.
Fact: The full benefits for spasticity may take several days to weeks of regular dosing to become noticeable. The dose is usually increased gradually.
🔄 Alternative Options
Generic Alternatives
- Baclofen 5 mg tablet
Brand Alternatives
- Liofen 5 Tablet