Cip-zox Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is blofen mr tablet used for?
This medicine is a combination of Chlorzoxazone (a muscle relaxant) and Diclofenac (an NSAID) used for short-term relief of painful musculoskeletal conditions such as muscle spasms, strains, and low back pain. It works by relaxing muscles and reducing inflammation. Take it with food to reduce stomach upset and avoid alcohol.
- Generic Name: Chlorzoxazone + Diclofenac
- Manufacturer: Casca Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 blofen mr tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोरज़ोक्साज़ोन और डाइक्लोफेनाक का संयोजन है, जिसका उपयोग मांसपेशियों में ऐंठन, खिंचाव, मोच और कमर दर्द जैसी मस्कुलोस्केलेटल समस्याओं के अल्पकालिक उपचार के लिए किया जाता है। यह मांसपेशियों को आराम देती है और सूजन तथा दर्द को कम करती है। इसे भोजन के साथ लेना चाहिए और शराब से बचना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, जी मिचलाना, पेट दर्द, अपच और सिरदर्द शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत विषाक्तता और गंभीर एलर्जी प्रतिक्रियाएँ शामिल हो सकती हैं। यदि काले या खूनी मल, खून की उल्टी, तेज पेट दर्द, सीने में दर्द, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या पेशाब कम आना जैसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक या उपचार की अवधि न बढ़ाएँ। इसे भोजन या दूध के साथ लें ताकि पेट की जलन कम हो। शराब और अन्य नींद लाने वाली दवाओं से बचें। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएँ। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। बच्चों की पहुँच से दूर रखें।
💊 blofen mr tablet Uses & Benefits
[{"condition":"Musculoskeletal pain and muscle spasms","description":"Relieves pain and relaxes muscles in conditions such as strains, sprains, and back pain.","evidence":"Well-established"},{"condition":"Low back pain","description":"Reduces pain and inflammation associated with acute low back pain.","evidence":"Well-established"},{"condition":"Tension headache","description":"May help relieve tension-type headaches associated with muscle tightness.","evidence":"Limited"},{"condition":"Post-operative pain","description":"Used for short-term management of post-surgical musculoskeletal pain.","evidence":"Limited"}]
Off-label uses: [{"condition":"Fibromyalgia","description":"Sometimes prescribed off-label for muscle pain in fibromyalgia.","evidence":"Limited"},{"condition":"Temporomandibular joint disorders","description":"May be used off-label for jaw muscle spasms.","evidence":"Limited"}]
Primary treatment for: Musculoskeletal pain and muscle spasms
Also treats: Low back pain, Tension headache, Post-operative pain
📋 Drug Information
| Generic Name(s) | Chlorzoxazone + Diclofenac |
| Brand Name | Ache X Tablet |
| Manufacturer | Casca Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Muscle Relaxant + NSAID |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients. Chlorzoxazone is a centrally acting muscle relaxant that primarily acts on the spinal cord and brainstem to inhibit polysynaptic reflexes, thereby reducing skeletal muscle spasm. Diclofenac is a non-steroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, leading to decreased production of prostaglandins, which are mediators of pain and inflammation.
Mechanism Steps
💡 How to Take blofen mr tablet
Strength: Tablet containing Chlorzoxazone 500 mg and Diclofenac 50 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally two to three times daily, preferably with food or milk. The maximum daily dose should not exceed three tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration of treatment without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially drowsiness and gastrointestinal side effects. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | Maximum daily dose is 3 tablets (Chlorzoxazone 1500 mg + Diclofenac 150 mg) in 24 hours. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of blofen mr tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| Antihypertensives | Moderate | |
| SSRIs | Moderate | |
| Fluconazole | Moderate | |
| Disulfiram | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., aspirin, ibuprofen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (e.g., ACE inhibitors, ARBs, diuretics)
- CYP2C9 inhibitors (e.g., fluconazole)
- CYP2E1 inhibitors (e.g., disulfiram)
- Selective serotonin reuptake inhibitors (SSRIs)
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness and dizziness caused by chlorzoxazone and increase the risk of gastrointestinal bleeding and ulcers caused by diclofenac.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to chlorzoxazone, diclofenac, or any component of the formulation","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe renal impairment","Severe hepatic impairment","Third trimester of pregnancy","Coronary artery bypass graft (CABG) surgery perioperative period"]
⚠️ Warnings & Precautions
["Take with food or milk to reduce gastrointestinal irritation.","Avoid alcohol and other CNS depressants due to increased drowsiness.","Do not drive or operate machinery until you know how this medicine affects you.","Use with caution in elderly patients due to increased risk of GI bleeding and renal impairment.","Use with caution in patients with cardiovascular risk factors.","Do not use for more than 7-10 days unless directed by a doctor.","Inform your doctor if you have a history of ulcers, kidney or liver disease, or hypertension.","Monitor for signs of gastrointestinal bleeding, especially if taking anticoagulants or corticosteroids."]
🤱 Lactation Safety
Not established from the available information. Diclofenac is excreted in breast milk in small amounts. Chlorzoxazone safety during breastfeeding is not established. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe drowsiness, nausea, vomiting, gastrointestinal bleeding, and renal impairment. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs, renal and hepatic function, and manage complications accordingly.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or milk to reduce stomach upset. Avoid alcohol and other central nervous system depressants as they can increase drowsiness and the risk of stomach bleeding. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have a history of ulcers, kidney or liver disease, high blood pressure, or heart disease. Do not use this medicine for more than 7-10 days unless directed by your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at increased risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use with caution and consider lower doses. Monitor renal and hepatic function regularly.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester, due to risk of premature closure of the ductus arteriosus. If you are planning to become pregnant, consult your doctor to discuss alternative treatments.
🏥 Post-Surgery Considerations
This medicine may be used for short-term post-operative pain management. However, it should be used with caution after surgery due to increased risk of bleeding and kidney problems. Consult your surgeon before taking this medicine.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase the risk of bleeding. Your dentist may advise you to stop the medicine temporarily before surgery.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you experience drowsiness or dizziness. Gentle stretching and low-impact activities may be beneficial, but consult your doctor or physiotherapist before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness and dizziness, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how this medicine affects you. It is advisable to take rest and avoid strenuous activities during treatment.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience severe side effects such as gastrointestinal bleeding, severe abdominal pain, chest pain, difficulty breathing, swelling of face or throat, yellowing of skin or eyes, or decreased urination. Do not stop taking this medicine without consulting your doctor if you are feeling better, as the underlying condition may still need treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, liver toxicity, and cardiovascular events. It is not recommended for extended use beyond 7-10 days unless directed by a doctor. Regular monitoring of liver and kidney function may be required if used for longer periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve muscle strength and flexibility.
Evidence: Well-establishedApplying heat or cold packs can help relieve muscle spasm and pain.
Evidence: Well-establishedMay help reduce pain in some individuals.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. There are no known interactions between this medicine and vaccines. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight and moisture. If traveling across time zones, adjust dosing schedule gradually under medical advice. Check customs regulations for carrying prescription medicines. Do not pack in checked luggage; keep in carry-on bag.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain and muscle spasm within 30 minutes to 1 hour after taking it.
A: It is best taken with food or milk to reduce the risk of stomach upset and ulcers.
A: Do not take other NSAIDs or painkillers without consulting your doctor, as it may increase the risk of side effects.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Do not stop taking this medicine without consulting your doctor. Your doctor will advise you on the appropriate duration of treatment.
🤔 Common Patient Concerns
🔄 Substitutes for blofen mr tablet
View AllAlternative brands with exact same active ingredient:
-
lupizox 500 mg/50 mg/500 mg tabletLupin Ltd ₹8.65 67% CHEAPER
-
ko bizox tabletKopran Ltd ₹8.82 66.4% CHEAPER
-
infazox tabletAgron Remedies Pvt Ltd ₹9.38 64.3% CHEAPER
-
mofax 500 mg/50 mg/500 mg tabletSun Pharmaceutical Industries Ltd ₹18.94 27.8% CHEAPER
-
dipkon cx tabletBriskon Laboratories ₹25.31 3.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: This medicine is intended for short-term use only, usually not exceeding 7-10 days, unless directed by a doctor. - Myth: This medicine is safe to take without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. - Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food or milk to reduce the risk of stomach upset and ulcers.
🔄 Alternative Options
Generic Alternatives
- Chlorzoxazone + Diclofenac combination tablets
Brand Alternatives
- Cip-zox tablet