bkdol tablet - Tramadol (37.5mg) + Paracetamol (325mg) medicine

Bkdol Tablet - Uses, Price, Side Effects

4.5 (15 reviews)
๐Ÿญ Biokindle Lifesciences Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is bkdol tablet used for?

Bkdol Tablet is a combination of Tramadol (37.5mg) and Paracetamol (325mg) used for moderate to severe pain. Tramadol works by binding to opioid receptors in the brain, while Paracetamol reduces pain and fever by inhibiting COX enzymes. It provides effective pain relief for conditions like arthritis, back pain, and post-surgical pain.

  • Generic Name: Tramadol + Paracetamol
  • Manufacturer: Biokindle Lifesciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š bkdol tablet Uses & Benefits

Moderate to severe pain, acute pain, postoperative pain

Off-label uses: Chronic pain, neuropathic pain

๐Ÿ“‹ Drug Information

Generic Name(s)Tramadol + Paracetamol
Brand NameAnadol P
ManufacturerBiokindle Lifesciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassOpioid analgesic + Non-opioid analgesic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract
DistributionWidely distributed; crosses placenta and blood-brain barrier
Protein BindingTramadol: ~20%; Paracetamol: ~10-25%
MetabolismTramadol: Hepatic via CYP2D6 and CYP3A4 to active metabolite O-desmethyltramadol; Paracetamol: Hepatic via glucuronidation and sulfation
Half-LifeTramadol: 5-7 hours; Paracetamol: 1.5-2.5 hours
ExcretionRenal (tramadol and metabolites); Renal (paracetamol metabolites)
BioavailabilityTramadol: ~75%; Paracetamol: ~88%
Onset of ActionTramadol: 30-60 minutes; Paracetamol: 30-60 minutes
Peak Plasma TimeTramadol: 1-2 hours; Paracetamol: 0.5-1 hour
Duration of ActionTramadol: 4-6 hours; Paracetamol: 4-6 hours

How It Works

Tramadol: Binds to mu-opioid receptors and inhibits serotonin/norepinephrine reuptake; Paracetamol: Inhibits COX enzymes in the CNS, reducing prostaglandin synthesis

Mechanism Steps

1Tramadol binds to mu-opioid receptors in the CNS, inhibiting pain transmission
2Tramadol inhibits serotonin and norepinephrine reuptake, enhancing descending pain modulation
3Paracetamol inhibits COX enzymes in the CNS, reducing prostaglandin synthesis and pain perception

๐Ÿ’ก How to Take bkdol tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of bkdol tablet

โœ… Common Side Effects

  • Nausea
  • Dizziness
  • Drowsiness
  • Constipation
  • Headache
  • Sweating

๐Ÿšจ Serious Side Effects

  • Respiratory depression
  • Seizures
  • Serotonin syndrome
  • Hepatotoxicity
  • Hypotension

โš ๏ธ Rare Side Effects

  • QT prolongation
  • Adrenal insufficiency
  • Anaphylaxis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
MAOIs Major Risk of serotonin syndrome
Alcohol Moderate Increased liver toxicity

๐Ÿšจ Major Interactions

  • MAOIs
  • SSRIs
  • SNRIs
  • TCAs
  • CNS depressants
  • Carbamazepine
  • Rifampin

โšก Moderate Interactions

  • Warfarin
  • Anticoagulants
  • Alcohol
  • Antiepileptics
  • CYP2D6 inhibitors

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Metoclopramide

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; avoid grapefruit juice (CYP3A4 inhibition)

๐Ÿท Alcohol Interaction

Increased CNS depression and hepatotoxicity risk

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, acute opioid intoxication, severe respiratory depression, MAOI use within 14 days, severe hepatic impairment

๐Ÿ“Š Monitoring Parameters

Pain relief, respiratory rate, liver function, renal function, signs of serotonin syndrome

๐Ÿคฑ Lactation Safety

Use with caution; tramadol excreted in breast milk

๐Ÿ’Š Overdose Management

Naloxone for tramadol; N-acetylcysteine for paracetamol; supportive care

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

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