biospaaz 325mg/250mg tablet - Uses, Price, Side Effects & Substitutes
What is biospaaz 325mg/250mg tablet used for?
Biospaaz 325mg/250mg Tablet (Paracetamol + Chlorzoxazone) is used to treat PAIN ANALGESICS. It contains Paracetamol (325mg) + Chlorzoxazone (250mg), which Paracetamol: Inhibits cyclooxygenase (COX) in the CNS, reducing prostaglandin sy. Always consult your doctor before use. Take as prescribed.
- Generic Name: Paracetamol + Chlorzoxazone
- Manufacturer: Best Biotech
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ biospaaz 325mg/250mg tablet Uses & Benefits
๐ Drug Information
| Generic Name(s) | Paracetamol + Chlorzoxazone |
| Brand Name | Biospaaz 325mg/250mg Tablet |
| Manufacturer | Best Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Pain Analgesics |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Paracetamol: Inhibits cyclooxygenase (COX) in the CNS, reducing prostaglandin synthesis; Chlorzoxazone: Depresses polysynaptic reflexes at spinal and subcortical levels, possibly by inhibiting calcium influx.
Mechanism Steps
๐ก How to Take biospaaz 325mg/250mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of biospaaz 325mg/250mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Dizziness
- Drowsiness
- Headache
- Rash
๐จ Serious Side Effects
- Hepatotoxicity
- Stevens-Johnson syndrome
- Anaphylaxis
- Bone marrow suppression
โ ๏ธ Rare Side Effects
- Thrombocytopenia
- Agranulocytosis
- Pancreatitis
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | Increased hepatotoxicity risk |
| Warfarin | Major | Increased INR and bleeding risk |
| Isoniazid | Major | Increased hepatotoxicity risk |
| Rifampin | Major | Reduced paracetamol efficacy and increased hepatotoxicity |
| Carbamazepine | Moderate | Reduced paracetamol efficacy |
| Phenytoin | Moderate | Reduced paracetamol efficacy |
| Barbiturates | Moderate | Reduced paracetamol efficacy |
| Oral contraceptives | Moderate | Reduced paracetamol efficacy |
| Cholestyramine | Minor | Reduced paracetamol absorption |
| Metoclopramide | Minor | Increased paracetamol absorption |
| Propranolol | Minor | Increased paracetamol bioavailability |
๐จ Major Interactions
- Alcohol
- Warfarin
- Isoniazid
- Rifampin
โก Moderate Interactions
- Carbamazepine
- Phenytoin
- Barbiturates
- Oral contraceptives
โน๏ธ Minor Interactions
- Cholestyramine
- Metoclopramide
- Propranolol
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid high-fat meals.
๐ท Alcohol Interaction
Increased risk of hepatotoxicity with chronic alcohol use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component, severe hepatic impairment, severe renal impairment, G6PD deficiency (paracetamol).
๐ Monitoring Parameters
Liver function tests, renal function, CBC, signs of hepatotoxicity.
๐คฑ Lactation Safety
Paracetamol: Safe in usual doses; Chlorzoxazone: Not recommended.
๐ Overdose Management
Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for chlorzoxazone.
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double.