biorubin 10mg injection
What is biorubin 10mg injection used for?
Alrubicin (Epirubicin) is used to treat ANTI NEOPLASTICS. It contains Epirubicin (10mg), which Intercalates between DNA base pairs, inhibits topoisomerase II, and generates fr. Always consult your doctor before use. Take as prescribed.
- Generic Name: Epirubicin
- Manufacturer: Biochem Pharmaceutical Industries
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ biorubin 10mg injection Uses & Benefits
Breast cancer, ovarian cancer, gastric cancer, lung cancer, lymphomas, leukemias.
Off-label uses: Bladder cancer, soft tissue sarcoma, multiple myeloma.
๐ Drug Information
| Generic Name(s) | Epirubicin |
| Brand Name | Alrubicin |
| Manufacturer | Biochem Pharmaceutical Industries |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkaloids-cytotoxic agents |
| Route of Administration | Intravenous |
| Storage | Store at 2-8ยฐC, protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Intercalates between DNA base pairs, inhibits topoisomerase II, and generates free radicals leading to DNA damage and cell death.
Mechanism Steps
๐ก How to Take biorubin 10mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of biorubin 10mg injection
โ Common Side Effects
- Nausea
- vomiting
- alopecia
- myelosuppression
- mucositis
- fatigue
๐จ Serious Side Effects
- Cardiotoxicity
- secondary leukemia
- severe myelosuppression
- hepatotoxicity
- tumor lysis syndrome
โ ๏ธ Rare Side Effects
- Anaphylaxis
- radiation recall
- extravasation necrosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Trastuzumab | Major | Increased risk of cardiotoxicity |
| Cyclophosphamide | Major | Increased risk of hemorrhagic cystitis and cardiotoxicity |
| Paclitaxel | Major | Increased myelosuppression |
| Doxorubicin | Major | Additive cardiotoxicity |
| Verapamil | Moderate | Increased epirubicin levels |
| Cimetidine | Moderate | Decreased clearance of epirubicin |
| Phenobarbital | Moderate | Increased metabolism of epirubicin |
| Dexamethasone | Minor | Possible minor interaction |
| Metoclopramide | Minor | Possible minor interaction |
๐จ Major Interactions
- Trastuzumab
- Cyclophosphamide
- Paclitaxel
- Doxorubicin
โก Moderate Interactions
- Verapamil
- Cimetidine
- Phenobarbital
โน๏ธ Minor Interactions
- Dexamethasone
- Metoclopramide
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
May increase hepatotoxicity risk; avoid alcohol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to epirubicin, severe hepatic impairment, severe myocardial insufficiency, recent myocardial infarction, severe arrhythmias, previous treatment with maximum cumulative doses of anthracyclines.
๐ Monitoring Parameters
CBC, liver function tests, renal function, cardiac function (LVEF), ECG.
๐คฑ Lactation Safety
Contraindicated; discontinue nursing.
๐ Overdose Management
Supportive care, monitor for myelosuppression and cardiotoxicity; no specific antidote.
โฐ Missed Dose
Do not double dose; consult physician.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for biorubin 10mg injection
View AllAlternative brands with exact same active ingredient (Epirubicin (10mg)):
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anthracin 10mg injectionDabur India Ltd โน15.10 94.3% CHEAPER
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epineon 10mg injectionNeon Laboratories Ltd โน169.77 35.7% CHEAPER
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epithra 10mg injectionGlenmark Pharmaceuticals Ltd โน251.00 5% CHEAPER
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innorubicin 10mg injectionInnova Formulations Pvt Ltd โน255.37 3.3% CHEAPER
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erubin 10mg injectionRPG Life Sciences Ltd โน258.00 2.3% CHEAPER
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epiruba 10mg injectionGetwell Oncology Pvt Ltd โน290.00 9.8% COSTLIER
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epichlor 10 injectionKhandelwal Laboratories Pvt Ltd โน304.48 15.3% COSTLIER
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alrubicin 10mg injectionAlkem Laboratories Ltd โน320.00 21.1% COSTLIER
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epicure 10mg injectionEmcure Pharmaceuticals Ltd โน333.00 26.1% COSTLIER
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adricin 10mg injectionAdley Formulations โน339.64 28.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.