biopram 0.5mg/10mg tablet
What is biopram 0.5mg/10mg tablet used for?
Atease ES (Etizolam + Escitalopram Oxalate) is used to treat NEURO CNS. It contains Etizolam (0.5mg) + Escitalopram Oxalate (10mg), which Etizolam: Enhances GABA-A receptor activity; Escitalopram: Selectively inhibits . Always consult your doctor before use. Take as prescribed.
- Generic Name: Etizolam + Escitalopram Oxalate
- Manufacturer: Vision Biolife Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ biopram 0.5mg/10mg tablet Uses & Benefits
Generalized anxiety disorder, panic disorder, major depressive disorder with anxiety
Off-label uses: Premenstrual dysphoric disorder, social anxiety disorder
๐ Drug Information
| Generic Name(s) | Etizolam + Escitalopram Oxalate |
| Brand Name | Atease ES |
| Manufacturer | Vision Biolife Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Benzodiazepine + SSRI |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Etizolam: Enhances GABA-A receptor activity; Escitalopram: Selectively inhibits serotonin reuptake
Mechanism Steps
๐ก How to Take biopram 0.5mg/10mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of biopram 0.5mg/10mg tablet
โ Common Side Effects
- Drowsiness
- Dizziness
- Nausea
- Dry mouth
- Fatigue
- Insomnia
๐จ Serious Side Effects
- Serotonin syndrome
- Suicidal thoughts
- Seizures
- Severe allergic reactions
- QT prolongation
โ ๏ธ Rare Side Effects
- Hepatic failure
- Agranulocytosis
- Angle-closure glaucoma
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Risk of serotonin syndrome |
| Alcohol | Major | Increased sedation and CNS depression |
| Warfarin | Moderate | Increased bleeding risk |
| Ketoconazole | Major | Increased etizolam levels |
๐จ Major Interactions
- MAOIs
- Linezolid
- Methylene Blue
- CYP3A4 inhibitors (e.g., Ketoconazole)
- CNS depressants (e.g., Alcohol, Opioids)
โก Moderate Interactions
- CYP2C19 inhibitors (e.g., Omeprazole)
- CYP2D6 inhibitors (e.g., Fluoxetine)
- Anticoagulants (e.g., Warfarin)
- NSAIDs
โน๏ธ Minor Interactions
- Cimetidine
- Oral contraceptives
- Grapefruit juice
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase etizolam levels; avoid alcohol
๐ท Alcohol Interaction
Avoid; increased CNS depression and sedation
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, narrow-angle glaucoma, concurrent MAOI use, severe hepatic impairment, myasthenia gravis
๐ Monitoring Parameters
Liver function, renal function, ECG, suicidal ideation, sedation level
๐คฑ Lactation Safety
Not recommended; both drugs excreted in breast milk
๐ Overdose Management
Supportive care; flumazenil for etizolam overdose; serotonin syndrome management
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose