biomef tx tablet - Tranexamic Acid (500mg) + Mefenamic Acid (250mg) medicine

biomef tx tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Biosafe Formulations ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is biomef tx tablet used for?

Abdotic Plus Tablet (Tranexamic Acid + Mefenamic Acid) is used to treat BLOOD RELATED. It contains Tranexamic Acid (500mg) + Mefenamic Acid (250mg), which Tranexamic acid: inhibits plasminogen activation; Mefenamic acid: inhibits COX-1. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Tranexamic Acid + Mefenamic Acid
  • Manufacturer: Biosafe Formulations
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š biomef tx tablet Uses & Benefits

Menorrhagia, dysmenorrhea, heavy menstrual bleeding

Off-label uses: Epistaxis, dental bleeding, trauma-related bleeding

๐Ÿ“‹ Drug Information

Generic Name(s)Tranexamic Acid + Mefenamic Acid
Brand NameAbdotic Plus Tablet
ManufacturerBiosafe Formulations
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassAntifibrinolytic + NSAID
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely; crosses placenta
Protein BindingTranexamic acid: ~3%; Mefenamic acid: >90%
MetabolismTranexamic acid: minimal hepatic; Mefenamic acid: hepatic via CYP2C9
Half-LifeTranexamic acid: 2-11 hours; Mefenamic acid: 2-4 hours
ExcretionTranexamic acid: renal (90% unchanged); Mefenamic acid: renal and biliary
BioavailabilityTranexamic acid: ~34%; Mefenamic acid: ~90%
Onset of ActionTranexamic acid: 2-3 hours; Mefenamic acid: 1-2 hours
Peak Plasma TimeTranexamic acid: 3 hours; Mefenamic acid: 2-4 hours
Duration of ActionTranexamic acid: 6-8 hours; Mefenamic acid: 4-6 hours

How It Works

Tranexamic acid: inhibits plasminogen activation; Mefenamic acid: inhibits COX-1/COX-2

Mechanism Steps

1Tranexamic acid reversibly binds to plasminogen, blocking its conversion to plasmin
2Inhibition of fibrinolysis stabilizes blood clots
3Mefenamic acid inhibits cyclooxygenase (COX-1 and COX-2) enzymes

๐Ÿ’ก How to Take biomef tx tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of biomef tx tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Headache

๐Ÿšจ Serious Side Effects

  • Thrombosis
  • Anaphylaxis
  • GI bleeding
  • Renal failure

โš ๏ธ Rare Side Effects

  • Color vision disturbance
  • Hypotension
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Major Additive antiplatelet effect
Clopidogrel Major Increased bleeding risk
Heparin Major Increased bleeding risk
NSAIDs Major Additive GI toxicity
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect
Lithium Moderate Increased lithium levels
Methotrexate Moderate Increased methotrexate toxicity
Antacids Minor Reduced absorption
Corticosteroids Minor Increased GI ulcer risk

๐Ÿšจ Major Interactions

  • Warfarin
  • Aspirin
  • Clopidogrel
  • Heparin
  • NSAIDs

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Lithium
  • Methotrexate

โ„น๏ธ Minor Interactions

  • Antacids
  • Corticosteroids

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Active peptic ulcer, severe renal impairment, history of hypersensitivity, thromboembolic disease

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, CBC, signs of bleeding

๐Ÿคฑ Lactation Safety

Use with caution; excreted in milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal

โฐ Missed Dose

Take as soon as remembered; skip if near next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

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