biogest 200mg soft gelatin capsule - Progesterone (200mg) medicine

Algest SR 200 Tablet (Progesterone 200 mg Intramuscular Injection)

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🏭 Biocin Genetics & Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Progesterone is used in pregnancy for specific indications such as luteal support. It should only be used when prescribed by a specialist. The old FDA letter categories are no longer used; evidence-based guidance should be followed. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate to well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Chest pain or severe leg pain and swelling
  • Yellowing of skin or eyes
  • Severe abdominal pain
  • Unusual vaginal bleeding
  • Severe headache with vision changes
  • High fever with chills

If experiencing severe symptoms, call emergency services immediately.

What is biogest 200mg soft gelatin capsule used for?

This medicine contains progesterone 200 mg and is given by intramuscular injection. It is used for luteal support in fertility treatments, threatened miscarriage, and certain menstrual disorders. It must be administered by a healthcare professional.

  • Generic Name: Progesterone (Natural Micronized)
  • Manufacturer: Biocin Genetics & Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 biogest 200mg soft gelatin capsule के बारे में (Hindi Summary)

उपयोग: यह दवा प्रोजेस्टेरोन 200 मिलीग्राम इंजेक्शन के रूप में दी जाती है। इसका उपयोग फर्टिलिटी ट्रीटमेंट में ल्यूटियल सपोर्ट, गर्भपात के खतरे, और कुछ मासिक धर्म विकारों में किया जाता है। यह इंजेक्शन डॉक्टर या नर्स द्वारा मांसपेशी में लगाया जाता है। इसे मुंह से नहीं लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, लालिमा, सूजन, सिरदर्द, चक्कर आना, नींद आना, मनोदशा में बदलाव, स्तन में कोमलता, मतली और मासिक धर्म में बदलाव शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन खून के थक्के, गंभीर एलर्जी, और लीवर की समस्या हो सकती है। कोई भी गंभीर लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा इंजेक्शन के रूप में दी जानी चाहिए। इसे मुंह से न लें। अपने डॉक्टर को सभी दवाओं के बारे में बताएं, खासकर खून पतला करने वाली दवाएं। खून के थक्के, लीवर रोग, या स्तन कैंसर का इतिहास हो तो डॉक्टर को बताएं। शराब से बचें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। असामान्य रक्तस्राव, तेज सिरदर्द, दृष्टि में बदलाव, या पैर में सूजन हो तो तुरंत डॉक्टर से मिलें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 biogest 200mg soft gelatin capsule Uses & Benefits

[{"condition":"Luteal phase support in assisted reproduction","description":"This medicine is used to support the uterine lining after ovulation induction or embryo transfer in IVF and other fertility treatments.","evidence":"Well-established"},{"condition":"Threatened miscarriage due to luteal phase deficiency","description":"Progesterone supplementation may help maintain early pregnancy when low progesterone is suspected.","evidence":"Moderate"},{"condition":"Recurrent miscarriage associated with luteal phase defect","description":"Used in selected patients to support early pregnancy maintenance.","evidence":"Limited to moderate"},{"condition":"Secondary amenorrhea","description":"Progesterone can be used to induce withdrawal bleeding in women with absent periods due to hormonal imbalance.","evidence":"Well-established"},{"condition":"Abnormal uterine bleeding due to hormonal imbalance","description":"Helps stabilize the endometrium and regulate bleeding in selected non-structural causes.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Luteal support in unexplained infertility","description":"Sometimes prescribed off-label to support the luteal phase in women with unexplained infertility.","evidence":"Limited"},{"condition":"Prevention of preterm birth in selected high-risk women","description":"Progesterone has been studied for preterm birth prevention, but this is not a standard labeled use for all products.","evidence":"Limited"}]

Primary treatment for: Luteal phase support in assisted reproduction

Also treats: Threatened miscarriage, Recurrent miscarriage, Secondary amenorrhea, Abnormal uterine bleeding

📋 Drug Information

Generic Name(s)Progesterone (Natural Micronized)
Brand NameAqsusten 25 Solution for Injection
ManufacturerBiocin Genetics & Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassNatural Progesterone
Route of AdministrationIntramuscular
StorageStore in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Shelf LifeNot established from the available information for this specific product. Check the expiry date on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
This medicine must be administered by a healthcare professional as an intramuscular injection.
2
Do not attempt to take this medicine orally.
3
Inform your doctor about all other medicines, especially blood thinners and hormone therapies.
4
Avoid alcohol while using this medicine because it can increase drowsiness and dizziness.
5
Report any pain, redness, or swelling at the injection site to your doctor.
6
Keep all follow-up appointments and report any unusual vaginal bleeding or severe headache.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Luteal phase deficiency
This medicine is commonly prescribed for this.
Likely Use
✅
Threatened miscarriage
May be used under specialist supervision.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAfter intramuscular injection, progesterone is absorbed from the injection site into the bloodstream. The exact absorption rate depends on the formulation, injection site, and individual patient factors. Not established from the available information for this specific product.
DistributionProgesterone is widely distributed in the body, with high concentrations in fat tissue and reproductive organs. It crosses the placenta and is present in breast milk. Not established from the available information for this specific product.
Protein BindingProgesterone is highly bound to plasma proteins, mainly albumin and corticosteroid-binding globulin. Not established from the available information for this specific product.
MetabolismProgesterone is metabolized primarily in the liver by cytochrome P450 enzymes, including CYP3A4, into various metabolites such as pregnanediol and pregnanolone. Not established from the available information for this specific product.
Half-LifeNot established from the available information for this specific product.
ExcretionProgesterone metabolites are excreted mainly in urine and bile, with some enterohepatic circulation. Not established from the available information for this specific product.
BioavailabilityNot established from the available information for this specific product.
Onset of ActionNot established from the available information for this specific product.
Peak Plasma TimeNot established from the available information for this specific product.
Duration of ActionNot established from the available information for this specific product.

How It Works

This medicine works by delivering progesterone, which binds to intracellular progesterone receptors in target tissues such as the endometrium, myometrium, breast, and brain. This binding activates gene transcription and changes protein synthesis, leading to secretory transformation of the endometrium, relaxation of uterine smooth muscle, and feedback regulation of the hypothalamic-pituitary-ovarian axis. These effects help support implantation and early pregnancy, regulate menstrual bleeding, and suppress ovulation when used in certain regimens.

Mechanism Steps

1
Binding to progesterone receptor: Progesterone enters target cells and binds to the nuclear progesterone receptor.
2
Receptor activation and gene transcription: The hormone-receptor complex moves into the nucleus and regulates transcription of specific genes.
3
Endometrial transformation: This leads to secretory changes in the endometrium that support implantation and pregnancy maintenance.
4
Uterine relaxation: Progesterone reduces myometrial contractility, helping to maintain pregnancy.
5
Hypothalamic-pituitary feedback: Progesterone modulates gonadotropin release, which can affect ovulation and the menstrual cycle.

💡 How to Take biogest 200mg soft gelatin capsule

Strength: 200 mg tablet for intramuscular use

1This medicine is given by a healthcare professional as an intramuscular injection.
2Do not attempt to take this medicine orally.
3The injection is usually given into a large muscle such as the buttock or thigh.
4Follow your doctor's schedule exactly.
5Report any pain, redness, or swelling at the injection site.

Dosage Information

Adult DosageThe dose of this medicine is individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. For luteal support, a common regimen may involve 200 mg intramuscularly at specific intervals as prescribed. Do not self-administer. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the sedative effects of this medicine. Use with caution and individualize the dose under medical supervision.
Renal ImpairmentNo specific dose adjustment is established for renal impairment. Use with caution and monitor as clinically indicated.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose adjustment may be needed based on clinical response and liver function tests.
Maximum Daily DoseNot established from the available information for this specific product. Follow the prescribed dose exactly.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Grapefruit
Avoid large amounts
May increase progesterone levels by inhibiting CYP3A4.
Alcohol
Avoid
May increase drowsiness and dizziness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Contact your healthcare provider to reschedule the injection as soon as possible.
💡 Do not attempt to self-administer.
📌 More than half the dosing interval has passed
→ Skip the missed dose and continue with the regular schedule.
💡 Do not double the dose to catch up.

⚠️ Side Effects of biogest 200mg soft gelatin capsule

✅ Common Side Effects

Injection site pain, redness, or swelling (Common (up to 30%))
Apply a cold pack if advised by your nurse. Report severe pain or swelling to your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult your doctor if headaches are severe or persistent.
Drowsiness or dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Breast tenderness (Common (5-10%))
Wear a supportive bra. Consult your doctor if pain is severe.
Nausea (Common (5-10%))
Take small frequent meals. Inform your doctor if vomiting occurs.
Mood changes or irritability (Common (5-10%))
Discuss with your doctor if mood changes affect daily life.

🚨 Serious Side Effects

Blood clots (deep vein thrombosis or pulmonary embolism) (Rare (<0.1%))
Seek immediate medical attention for leg swelling, chest pain, or difficulty breathing.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services for swelling of face, lips, throat, or difficulty breathing.
Liver problems (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain immediately.
Injection site abscess (Rare (<0.1%))
Seek medical care for increasing pain, redness, warmth, or pus at the injection site.

⚠️ Rare Side Effects

Visual disturbances
Consult an eye specialist and inform your doctor.
Severe depression
Seek mental health support and contact your doctor immediately.
Unusual hair loss
Discuss with your doctor if hair loss is distressing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Rifampicin Major
Ketoconazole Major
Benzodiazepines Moderate
Insulin Moderate

🚨 Major Interactions

  • Warfarin
  • CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin)
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

  • Benzodiazepines
  • Antidiabetic medicines

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness caused by this medicine. It is best to avoid alcohol while using this medicine, especially before driving or operating machinery.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to progesterone or any ingredient in the product","Unexplained vaginal bleeding","History of blood clots or thromboembolic disorders","Severe liver disease","Known or suspected breast cancer","Missed abortion or non-viable pregnancy unless specifically advised"]

⚠️ Warnings & Precautions

["This medicine must be given by a healthcare professional as an intramuscular injection.","Do not take this medicine orally.","Use with caution in patients with a history of blood clots, liver disease, or migraine.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Do not share this medicine with others."]

🤱 Lactation Safety

Progesterone is present in breast milk. Consult your doctor before using this medicine while breastfeeding. It is generally not recommended unless specifically advised by a specialist.

💊 Overdose Management

Overdose with this medicine is unlikely to cause serious harm because it is given by injection under medical supervision. If accidental overdose occurs, seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a scheduled dose, contact your healthcare provider as soon as possible. Do not double the dose to catch up. Your doctor will advise on the next step based on your treatment plan.

Additional Safety Advice

General Safety

This medicine must be given only by a healthcare professional as an intramuscular injection. Do not attempt to take it orally or self-inject. Inform your doctor about all your medicines, especially blood thinners, other hormones, and medicines for seizures or diabetes. Tell your doctor if you have a history of blood clots, liver disease, migraine with aura, or breast cancer. Avoid alcohol while using this medicine because it can worsen drowsiness and dizziness. Use effective contraception if pregnancy is not desired, and do not use this medicine during pregnancy unless specifically prescribed for luteal support. Keep all follow-up appointments and report any unusual vaginal bleeding, severe headache, vision changes, or leg swelling immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the sedative effects. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. It may be prescribed for luteal support in certain cases.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before any surgery. It may affect blood clotting and interact with other medicines.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure. It may affect bleeding and interact with other medicines.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to support hormonal balance.
🥗
Engage in regular low-impact exercise as advised by your doctor.
😴
Avoid alcohol and smoking.
💧
Get adequate sleep and manage stress.
🧘
Follow a balanced diet rich in fruits and vegetables.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy or drowsy after the injection. Consult your doctor before starting any new exercise routine.

🥗 Diet Recommendations

Include plenty of fruits and vegetables
Stay well hydrated
Limit caffeine and alcohol
Choose whole grains and lean proteins

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how it affects you. Inform your employer if your work involves such activities.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Your doctor will advise when to stop based on your condition and treatment response.

📅 Long-Term Use Effects

Long-term use of this medicine may require monitoring of liver function, blood clotting, and menstrual bleeding patterns. Prolonged use should be reviewed regularly by your doctor to assess benefits and risks.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral progesterone

Alternative route of administration for some indications.

Evidence: Well-established
Vaginal progesterone

Another route used for luteal support.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature below 30°C

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Since it is an intramuscular injection, it must be administered by a healthcare professional. If traveling, arrange for a clinic or hospital to give the injection at the scheduled time. Store it in a cool, dry place away from direct sunlight. Check customs regulations for carrying prescription medicines across borders.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman undergoing IVF treatment
She was prescribed this medicine for luteal phase support after embryo transfer. The injection was given by a nurse at the clinic. She experienced mild injection site pain and drowsiness, which improved over time. She followed her doctor's schedule strictly and reported no serious side effects.
💡 Lesson: Following the prescribed injection schedule and reporting side effects helps ensure safe and effective treatment.
👤 A 28-year-old woman with a history of recurrent miscarriage
She was started on this medicine in early pregnancy under specialist care. She was monitored regularly for signs of blood clots and liver problems. The pregnancy progressed well, and she delivered a healthy baby.
💡 Lesson: Regular monitoring and specialist supervision are important when using this medicine during pregnancy.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The onset of action depends on the indication and individual factors. Your doctor will monitor your response.

Q: Can I take this medicine orally?

A: No, this medicine is intended for intramuscular injection only.

Q: Is this medicine safe in pregnancy?

A: It may be used in pregnancy for specific indications under specialist supervision. Consult your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for biogest 200mg soft gelatin capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken as an oral tablet.
    Fact: This product is intended for intramuscular injection and should not be taken orally.
  • Myth: This medicine is safe for everyone.
    Fact: It is contraindicated in certain conditions such as unexplained vaginal bleeding and history of blood clots.

🔄 Alternative Options

Generic Alternatives

  • Progesterone 200 mg injection

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","strength":"200 mg","route":"Intramuscular","release":"Immediate release"},{"medicine":"Progesterone 100 mg injection","strength":"100 mg","route":"Intramuscular","release":"Immediate release"}]

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