Ascapil 12A Tablet DT: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
- Signs of liver injury (yellowing of eyes or skin, dark urine, severe abdominal pain)
- Severe skin rash or blistering
- Neurological symptoms (confusion, seizures, severe dizziness)
- Persistent vomiting or diarrhea leading to dehydration
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is biobend plus 12mg/400mg tablet used for?
This medicine is a combination of Ivermectin and Albendazole used to treat parasitic worm infections. It works by paralyzing and killing the parasites. It is taken orally, usually as a single dose or as prescribed by a doctor.
- Generic Name: Ivermectin + Albendazole
- Manufacturer: Biocin Genetics & Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 biobend plus 12mg/400mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा इवरमेक्टिन और अल्बेंडाजोल का संयोजन है, जिसका उपयोग परजीवी कीड़ों के संक्रमण के इलाज के लिए किया जाता है। यह पेट के कीड़े, स्ट्रॉन्गीलॉइडियासिस, स्केबीज और फाइलेरिया के इलाज में प्रभावी है। यह कीड़ों को पक्षाघात और मार देती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, सिरदर्द, चक्कर आना और थकान शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, यकृत की समस्या और तंत्रिका संबंधी लक्षण हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो इसका उपयोग न करें। बच्चों को 15 किलोग्राम से कम वजन पर न दें। दवा को सूखी जगह पर कमरे के तापमान पर रखें।
💊 biobend plus 12mg/400mg tablet Uses & Benefits
[{"condition":"Soil-transmitted helminthiasis","description":"Used for the treatment of intestinal worm infections such as roundworm, hookworm, and whipworm.","evidence":"Well-established"},{"condition":"Strongyloidiasis","description":"Ivermectin is the drug of choice for Strongyloides stercoralis infection; Albendazole provides additional coverage.","evidence":"Well-established"},{"condition":"Scabies","description":"Ivermectin is effective against scabies mites, especially in crusted scabies or when topical treatment fails.","evidence":"Well-established"},{"condition":"Lymphatic filariasis","description":"Ivermectin and Albendazole are used in mass drug administration programs to eliminate lymphatic filariasis.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Cutaneous larva migrans","description":"Albendazole and Ivermectin have been used off-label for creeping eruption caused by hookworm larvae.","evidence":"Limited"},{"condition":"Rosacea","description":"Ivermectin has been studied off-label for inflammatory rosacea, but the oral combination is not standard.","evidence":"Limited"}]
Primary treatment for: Soil-transmitted helminthiasis
Also treats: Strongyloidiasis, Scabies, Lymphatic filariasis
📋 Drug Information
| Generic Name(s) | Ivermectin + Albendazole |
| Brand Name | ABD Plus Tablet |
| Manufacturer | Biocin Genetics & Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Anthelmintics |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | WHO recommends ivermectin and albendazole for mass drug administration in lymphatic filariasis elimination programs and for soil-transmitted helminthiasis control. |
| ICMR Guideline | ICMR guidelines recommend albendazole for soil-transmitted helminthiasis and ivermectin for strongyloidiasis and scabies. Combination use may be considered in specific cases. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antiparasitic agents with distinct mechanisms. Ivermectin binds to glutamate-gated chloride channels in invertebrate nerve and muscle cells, causing hyperpolarization, paralysis, and death of parasites. Albendazole selectively binds to parasite beta-tubulin, inhibiting microtubule polymerization, which disrupts glucose uptake and leads to energy depletion and parasite death. Together, they provide broad-spectrum activity against nematodes, cestodes, and some ectoparasites.
Mechanism Steps
💡 How to Take biobend plus 12mg/400mg tablet
Strength: Tablet containing Ivermectin 12 mg and Albendazole 400 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (Ivermectin 12 mg + Albendazole 400 mg) orally as a single dose or as directed by your physician. For specific infections, the dose and duration may vary. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is recommended for elderly patients, but use with caution due to potential reduced liver and kidney function. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended dose is one tablet per day, but this may vary based on indication. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of biobend plus 12mg/400mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ketoconazole | Major | |
| Rifampin | Major | |
| Dexamethasone | Moderate | |
| Praziquantel | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Warfarin
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
⚡ Moderate Interactions
- Dexamethasone
- Praziquantel
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine as it may increase the risk of liver toxicity and worsen side effects like dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to ivermectin or albendazole","Pregnancy","Breastfeeding","Children under 15 kg","Severe liver impairment","Severe kidney impairment"]
⚠️ Warnings & Precautions
["Use with caution in patients with liver disease.","Use with caution in patients with kidney disease.","Avoid in pregnancy and breastfeeding.","May cause dizziness; avoid driving.","Do not use in children under 15 kg.","Report any signs of allergic reaction immediately."]
🤱 Lactation Safety
Not recommended during breastfeeding. Both drugs are excreted in breast milk and may affect the infant. Consult your doctor for alternatives.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, dizziness, and neurological symptoms. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not self-medicate. Swallow the tablet whole with water, preferably after a meal to reduce stomach upset. Avoid alcohol while taking this medicine as it may increase liver toxicity. Inform your doctor if you have liver or kidney disease, or if you are pregnant or breastfeeding. Do not share this medicine with others. Keep out of reach of children. Store at room temperature away from moisture and sunlight. If you miss a dose, take it as soon as you remember, but skip if it is almost time for the next dose. Do not double dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects. Use with caution and monitor liver and kidney function.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated in pregnancy. If you are planning pregnancy, consult your doctor for alternative treatments.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, as it may interact with other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. No specific precautions, but maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel dizzy or fatigued. Stay hydrated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
May cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how it affects you.
🛑 When to Stop This Medicine
Do not stop without consulting your doctor. If you experience severe side effects, seek medical advice immediately.
📅 Long-Term Use Effects
Long-term use is not recommended unless prescribed for specific chronic infections. Prolonged use may increase the risk of liver toxicity and neurological side effects. Regular monitoring of liver function is advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For scabies, topical permethrin is an alternative.
Evidence: Well-establishedFor intestinal worms, mebendazole is an alternative.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines. However, consult your doctor before vaccination if you are on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Declare it at customs if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The medicine starts working within hours, but symptom relief may take a few days. Follow your doctor's advice.
A: It is best taken with food to improve absorption and reduce stomach upset.
A: It is not recommended for children under 15 kg. Consult a pediatrician.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any stomach problem.
Fact: It is only effective against parasitic infections and should not be used for general stomach issues. - Myth: It is safe to take during pregnancy.
Fact: It is contraindicated in pregnancy as it may harm the fetus.
🔄 Alternative Options
Generic Alternatives
- Ivermectin 12 mg + Albendazole 400 mg tablet
Brand Alternatives
- Ascapil 12A Tablet DT