biobin 1000mg injection - Uses, Price, Side Effects & Substitutes
What is biobin 1000mg injection used for?
Arasid 1000mg Injection (Cytarabine) is used to treat ANTI NEOPLASTICS. It contains Cytarabine (1000mg), which Cytarabine is a pyrimidine nucleoside analog that inhibits DNA synthesis by comp. Always consult your doctor before use. Take as prescribed.
- Generic Name: Cytarabine
- Manufacturer: Biochem Pharmaceutical Industries
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ biobin 1000mg injection Uses & Benefits
Acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), non-Hodgkin lymphoma, meningeal leukemia.
Off-label uses: Myelodysplastic syndromes, solid tumors (e.g., ovarian cancer).
๐ Drug Information
| Generic Name(s) | Cytarabine |
| Brand Name | Arasid 1000mg Injection |
| Manufacturer | Biochem Pharmaceutical Industries |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimetabolites |
| Route of Administration | Intravenous (IV) infusion or intrathecal. |
| Storage | Store at 20-25ยฐC (68-77ยฐF). Protect from light. Do not freeze. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cytarabine is a pyrimidine nucleoside analog that inhibits DNA synthesis by competing with cytidine for incorporation into DNA, leading to chain termination and cell death.
Mechanism Steps
๐ก How to Take biobin 1000mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of biobin 1000mg injection
โ Common Side Effects
- Myelosuppression
- Nausea
- Vomiting
- Diarrhea
- Mucositis
- Fever
- Rash
๐จ Serious Side Effects
- Severe myelosuppression
- Infections
- Hepatotoxicity
- Neurotoxicity (cerebellar dysfunction)
- Acute respiratory distress syndrome (ARDS)
- Tumor lysis syndrome
โ ๏ธ Rare Side Effects
- Pancreatitis
- Pericarditis
- Anaphylaxis
- Hemolytic uremic syndrome
- Leukoencephalopathy
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Methotrexate | Major | Increased toxicity, especially hepatotoxicity and myelosuppression. |
| Flucytosine | Major | Antagonism of antifungal effect. |
| Cyclophosphamide | Major | Increased cardiotoxicity risk. |
| Vincristine | Major | Increased neurotoxicity. |
| Digoxin | Moderate | Reduced digoxin absorption. |
| Phenytoin | Moderate | Reduced phenytoin levels. |
| Warfarin | Moderate | Altered anticoagulation effect. |
| Allopurinol | Minor | Possible increased cytarabine toxicity. |
| Acetaminophen | Minor | Possible increased hepatotoxicity. |
๐จ Major Interactions
- Methotrexate
- Flucytosine
- Cyclophosphamide
- Vincristine
โก Moderate Interactions
- Digoxin
- Phenytoin
- Warfarin
โน๏ธ Minor Interactions
- Allopurinol
- Acetaminophen
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
Avoid alcohol due to increased hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cytarabine, severe bone marrow suppression, active infection, pregnancy.
๐ Monitoring Parameters
Complete blood count (CBC), liver function tests (LFTs), renal function tests, neurological assessment.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk.
๐ Overdose Management
Supportive care; monitor for myelosuppression, neurotoxicity, and hepatotoxicity. No specific antidote.
โฐ Missed Dose
Contact healthcare provider; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for biobin 1000mg injection
View AllAlternative brands with exact same active ingredient (Cytarabine (1000mg)):
-
cytaneon 1000mg injectionNeon Laboratories Ltd โน347.19 72% CHEAPER
-
cytarine 1000mg injectionFresenius Kabi India Pvt Ltd โน425.76 65.7% CHEAPER
-
oncotar 1000mg injectionUnited Biotech Pvt Ltd โน895.00 27.9% CHEAPER
-
cancyt 1000mg injectionMiracalus Pharma Pvt Ltd โน990.00 20.2% CHEAPER
-
cytraze 1000mg injectionKhandelwal Laboratories Pvt Ltd โน1,000.00 19.4% CHEAPER
-
arasid 1000mg injectionIntas Pharmaceuticals Ltd โน1,005.95 18.9% CHEAPER
-
cytalon 1000 injectionCelon Laboratories Ltd โน1,170.47 5.7% CHEAPER
-
cybin pf 1000mg injectionVhb Life Sciences Inc โน1,180.00 4.9% CHEAPER
-
cytosar 1000mg injectionPfizer Ltd โน1,320.34 6.4% COSTLIER
-
cytarabine 1000mg injectionPfizer Ltd โน1,634.07 31.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.