ampilox-lb capsule - Ampicillin (250mg) + Dicloxacillin (250mg) medicine

ampilox-lb capsule

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🏭 Biochem Pharmaceutical Industries 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is ampilox-lb capsule used for?

This medicine contains Ampicillin (250mg) + Dicloxacillin (250mg) and is used to treat ANTI INFECTIVES. Ampicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); . Always consult your doctor before use.

  • Generic Name: Ampicillin + Dicloxacillin
  • Manufacturer: Biochem Pharmaceutical Industries
  • Form: Allopathy
  • Pregnancy Category: Category B
  • Prescription Required: Yes
💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 ampilox-lb capsule Uses & Benefits

Treatment of infections caused by susceptible organisms: respiratory tract infections, urinary tract infections, skin and soft tissue infections, osteomyelitis, septicemia.

Off-label uses: Prophylaxis in dental procedures, Treatment of Lyme disease

📋 Drug Information

Generic Name(s)Ampicillin + Dicloxacillin
Brand NameAmpilox Capsule
ManufacturerBiochem Pharmaceutical Industries
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassPenicillin Antibiotics
Route of AdministrationOral
StorageStore at room temperature (20-25°C); protect from moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; absorption may be decreased by food.
DistributionDistributes widely into body tissues and fluids, including pleural, peritoneal, and synovial fluids; crosses placenta; enters breast milk.
Protein BindingAmpicillin: 20%, Dicloxacillin: 95-98%
MetabolismAmpicillin: Partially metabolized in liver; Dicloxacillin: Hepatic metabolism to active and inactive metabolites.
Half-LifeAmpicillin: 1-1.8 hours; Dicloxacillin: 0.6-0.8 hours
ExcretionAmpicillin: Primarily renal (90% unchanged); Dicloxacillin: Renal and biliary (30-60% unchanged in urine).
BioavailabilityAmpicillin: 30-55%; Dicloxacillin: 50-85%
Onset of Action1-2 hours
Peak Plasma TimeAmpicillin: 1-2 hours; Dicloxacillin: 1-1.5 hours
Duration of Action6-8 hours

How It Works

Ampicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); Dicloxacillin inhibits cell wall synthesis and is resistant to staphylococcal beta-lactamases.

Mechanism Steps

1Ampicillin binds to PBPs, inhibiting transpeptidation in cell wall synthesis.
2Dicloxacillin binds to PBPs and resists hydrolysis by staphylococcal beta-lactamases.
3Both drugs disrupt cell wall integrity, leading to bacterial lysis and death.

💡 How to Take ampilox-lb capsule

Follow your doctor's prescription exactly.

⚠️ Side Effects of ampilox-lb capsule

✅ Common Side Effects

Nausea
Diarrhea
Rash
Vomiting

🚨 Serious Side Effects

Anaphylaxis
Stevens-Johnson syndrome
Clostridioides difficile colitis
Seizures

⚠️ Rare Side Effects

Hemolytic anemia
Interstitial nephritis
Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Methotrexate Major Increased methotrexate toxicity
Warfarin Major Increased bleeding risk
Probenecid Major Decreased renal excretion of penicillins
Oral contraceptives Moderate Reduced contraceptive efficacy
Allopurinol Moderate Increased risk of skin rash
Aminoglycosides Moderate Synergistic antibacterial effect
Chloramphenicol Minor Antagonistic effect
Tetracyclines Minor Antagonistic effect

🚨 Major Interactions

  • Methotrexate
  • Warfarin
  • Probenecid

⚡ Moderate Interactions

  • Oral contraceptives
  • Allopurinol
  • Aminoglycosides

🍷 Alcohol Interaction

No direct interaction; avoid excessive alcohol due to general health.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to penicillins, cephalosporins, or any component.

🤱 Lactation Safety

Excreted in breast milk; use with caution.

💊 Overdose Management

Supportive care; hemodialysis may be effective.

⏰ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double.

🔄 Substitutes for ampilox-lb capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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