bigunyl 5mg/800mg tablet - Uses, Price, Side Effects & Substitutes
What is bigunyl 5mg/800mg tablet used for?
Aviglip MF Tablet (Glipizide + Metformin) is used to treat ANTI DIABETIC. It contains Glipizide (5mg) + Metformin (800mg), which Glipizide stimulates insulin release from pancreatic beta cells; Metformin decre. Always consult your doctor before use. Take as prescribed.
- Generic Name: Glipizide + Metformin
- Manufacturer: Diacardus Pharmacy Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ bigunyl 5mg/800mg tablet Uses & Benefits
Type 2 diabetes mellitus
Off-label uses: Polycystic ovary syndrome (metformin component)
๐ Drug Information
| Generic Name(s) | Glipizide + Metformin |
| Brand Name | Aviglip MF Tablet |
| Manufacturer | Diacardus Pharmacy Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Antidiabetic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Glipizide stimulates insulin release from pancreatic beta cells; Metformin decreases hepatic glucose production and increases insulin sensitivity
Mechanism Steps
๐ก How to Take bigunyl 5mg/800mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bigunyl 5mg/800mg tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Hypoglycemia
๐จ Serious Side Effects
- Lactic acidosis
- Severe hypoglycemia
- Hemolytic anemia
- Cholestatic jaundice
โ ๏ธ Rare Side Effects
- Disulfiram-like reaction
- Photosensitivity
- Leukopenia
- Thrombocytopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | Increased risk of hypoglycemia and lactic acidosis |
| Cimetidine | Major | Increased metformin levels |
| Rifampin | Major | Decreased glipizide efficacy |
| Beta-blockers | Major | Mask hypoglycemia symptoms |
| ACE inhibitors | Major | Increased hypoglycemic effect |
๐จ Major Interactions
- Alcohol
- Cimetidine
- Rifampin
- Beta-blockers
- ACE inhibitors
โก Moderate Interactions
- NSAIDs
- Diuretics
- Corticosteroids
- Oral contraceptives
โน๏ธ Minor Interactions
- Calcium channel blockers
- Isoniazid
๐ฝ๏ธ Food Interactions
Food may delay absorption of glipizide; metformin absorption decreased by food
๐ท Alcohol Interaction
Increased risk of hypoglycemia and lactic acidosis
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Renal impairment (eGFR <30 mL/min), metabolic acidosis, hypersensitivity, type 1 diabetes
๐ Monitoring Parameters
Blood glucose, HbA1c, renal function, liver function, lactic acid levels
๐คฑ Lactation Safety
Not recommended; metformin excreted in milk, glipizide unknown
๐ Overdose Management
Monitor blood glucose, treat hypoglycemia with oral glucose or IV dextrose, supportive care
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose