bicalpro 50mg tablet - Bicalutamide (50mg) medicine

Bicalpro 50mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Emcure Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is bicalpro 50mg tablet used for?

Bicalpro 50mg Tablet contains Bicalutamide, a non-steroidal anti-androgen used to treat prostate cancer. It works by blocking the effects of testosterone on prostate cancer cells, slowing tumor growth. It is often used in combination with other treatments like LHRH agonists.

  • Generic Name: Bicalutamide
  • Manufacturer: Emcure Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š bicalpro 50mg tablet Uses & Benefits

Treatment of prostate cancer (metastatic and locally advanced).

Off-label uses: Hirsutism, male pattern baldness (not FDA approved).

๐Ÿ“‹ Drug Information

Generic Name(s)Bicalutamide
Brand NameAblu
ManufacturerEmcure Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI NEOPLASTICS
Action ClassAndrogen receptor antagonist
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; bioavailability is approximately 100%.
DistributionExtensively distributed; high volume of distribution (~20 L/kg).
Protein Binding96% bound to plasma proteins, primarily albumin.
MetabolismExtensively metabolized in the liver via oxidation and glucuronidation; CYP3A4 is involved.
Half-LifeApproximately 5-6 days (active enantiomer).
ExcretionPrimarily excreted in urine (as metabolites) and feces.
Bioavailability~100%
Onset of ActionSeveral weeks for therapeutic effect.
Peak Plasma TimeAbout 31 hours (single dose).
Duration of ActionLong duration due to long half-life.

How It Works

Non-steroidal antiandrogen; competitively inhibits androgen binding to androgen receptors.

Mechanism Steps

1Bicalutamide enters prostate cancer cells.
2Binds competitively to androgen receptors (AR).
3Prevents androgen (testosterone/DHT) from binding to AR.

๐Ÿ’ก How to Take bicalpro 50mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of bicalpro 50mg tablet

โœ… Common Side Effects

  • Hot flashes
  • Gynecomastia
  • Breast pain
  • Asthenia
  • Constipation

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Interstitial pneumonitis
  • QT prolongation

โš ๏ธ Rare Side Effects

  • Photosensitivity
  • Angioedema
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
CYP3A4 substrates Moderate Altered metabolism of other drugs

๐Ÿšจ Major Interactions

  • Warfarin
  • CYP3A4 substrates
  • CYP3A4 inhibitors

โšก Moderate Interactions

  • Anticoagulants
  • Corticosteroids

โ„น๏ธ Minor Interactions

  • Grapefruit juice

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
High
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, pregnancy, women of childbearing potential.

๐Ÿ“Š Monitoring Parameters

PSA levels, liver function tests, serum testosterone.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in animal milk.

๐Ÿ’Š Overdose Management

No specific antidote; supportive care.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for bicalpro 50mg tablet

View All

Alternative brands with exact same active ingredient (Bicalutamide (50mg)):

Medical Note: Always consult your doctor before switching medications.

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