betaloc injection 5 ml - Metoprolol Tartrate (1mg) medicine

Betaloc Injection 5 ml: Complete Medicine Guide

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🏭 AstraZeneca 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe bradycardia (heart rate < 50 bpm)
  • Severe hypotension (systolic BP < 90 mmHg)
  • Signs of heart block (dizziness, fainting, irregular heartbeat)
  • Difficulty breathing or wheezing
  • Swelling of face, lips, or throat
  • Chest pain or worsening heart failure symptoms
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is betaloc injection 5 ml used for?

This medicine is a beta-1 selective blocker given intravenously to rapidly control heart rate and blood pressure in acute conditions like supraventricular tachycardia and hypertensive emergencies. It works by blocking beta-1 receptors in the heart, reducing heart rate and cardiac output. It must be administered by a healthcare professional in a monitored setting.

  • Generic Name: Metoprolol Tartrate
  • Manufacturer: AstraZeneca
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 betaloc injection 5 ml के बारे में (Hindi Summary)

उपयोग: यह दवा मेटोप्रोलोल टार्ट्रेट इंजेक्शन है, जिसका उपयोग अस्पताल में डॉक्टर द्वारा तेज दिल की धड़कन और उच्च रक्तचाप को तुरंत नियंत्रित करने के लिए किया जाता है। यह दिल के बीटा-1 रिसेप्टर्स को ब्लॉक करके दिल की गति और रक्तचाप को कम करती है। इसका उपयोग सुप्रावेंट्रिकुलर टैचीकार्डिया, एट्रियल फिब्रिलेशन, और हाइपरटेंसिव इमरजेंसी में किया जाता है। यह दवा केवल डॉक्टर की देखरेख में ही दी जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में धीमी हृदय गति, निम्न रक्तचाप, चक्कर आना, थकान, मतली और ठंडे हाथ-पैर शामिल हैं। गंभीर दुष्प्रभावों में गंभीर ब्रैडीकार्डिया, हृदय ब्लॉक, तीव्र हृदय विफलता, ब्रोंकोस्पाज्म और एनाफिलेक्सिस हो सकते हैं। इनके होने पर तुरंत डॉक्टर को सूचित करें।

सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा अस्पताल या क्लिनिक में निरंतर निगरानी में ही दी जानी चाहिए। इसे स्वयं न लगाएं। यदि आपको अस्थमा, सीओपीडी, मधुमेह, थायरॉइड विकार या परिधीय संवहनी रोग है, तो अपने डॉक्टर को बताएं। इस दवा को अचानक बंद न करें, क्योंकि इससे एनजाइना या दिल का दौरा पड़ सकता है। शराब से बचें। धीमी हृदय गति, गंभीर चक्कर, सांस लेने में कठिनाई या सूजन के लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 betaloc injection 5 ml Uses & Benefits

[{"condition":"Supraventricular tachycardia","description":"Used intravenously to rapidly control heart rate in acute supraventricular tachyarrhythmias.","evidence":"Well-established"},{"condition":"Atrial fibrillation or flutter with rapid ventricular response","description":"Administered to slow the ventricular rate in acute settings when oral therapy is not feasible.","evidence":"Well-established"},{"condition":"Hypertensive emergencies","description":"Used parenterally to lower blood pressure in severe hypertension when urgent control is needed.","evidence":"Well-established"},{"condition":"Acute myocardial infarction","description":"May be used intravenously in the acute phase of myocardial infarction to reduce heart rate and myocardial oxygen demand, followed by oral therapy.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Thyroid storm","description":"Occasionally used off-label to control heart rate in thyroid storm when other measures are insufficient.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Not typically used as an injection for this purpose; oral metoprolol may be prescribed off-label for migraine prevention.","evidence":"Limited"}]

Primary treatment for: Supraventricular tachycardia

Also treats: Atrial fibrillation, Atrial flutter, Hypertensive emergency, Acute myocardial infarction

📋 Drug Information

Generic Name(s)Metoprolol Tartrate
Brand NameBetaloc 25mg Tablet
ManufacturerAstraZeneca
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassBeta blocker- Cardioselective
Route of AdministrationParenteral (intravenous)
StorageStore at controlled room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and freezing. Keep in the original container until use.
Shelf LifeThe shelf life is typically 24 months from the date of manufacture, but refer to the product label for the exact expiration date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine slowly over 1-2 minutes to avoid sudden hypotension.
2
Monitor heart rate and blood pressure continuously during and after administration.
3
Have resuscitation equipment readily available in case of severe adverse reactions.
4
Assess for contraindications such as severe bradycardia or heart block before administration.
5
Consider transitioning to oral therapy once the patient is stable.
6
Educate patients on the importance of not stopping beta-blockers abruptly.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Rapid heart rate
This medicine is commonly used to control rapid heart rate.
Likely Use
High blood pressure
This medicine is used in hypertensive emergencies.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot applicable for intravenous administration, as absorption is bypassed and the drug is directly introduced into the systemic circulation.
DistributionThis medicine is widely distributed throughout the body, including the heart, lungs, liver, and kidneys. It crosses the blood-brain barrier and the placenta, and is excreted in breast milk.
Protein BindingApproximately 12% bound to plasma proteins.
MetabolismThis medicine undergoes extensive hepatic metabolism, primarily by the CYP2D6 enzyme, with some contribution from CYP3A4. The major metabolite is alpha-hydroxymetoprolol, which has weak beta-blocking activity.
Half-LifeThe elimination half-life is approximately 3 to 7 hours in healthy adults, but it may be prolonged in patients with hepatic impairment or poor CYP2D6 metabolizers.
ExcretionThis medicine and its metabolites are primarily excreted in the urine, with about 95% of the dose recovered in urine and less than 5% in feces. Only a small fraction is excreted unchanged.
BioavailabilityNot applicable for intravenous administration, as bioavailability is 100% by this route.
Onset of ActionThe onset of action following intravenous administration is rapid, typically within 5 to 10 minutes.
Peak Plasma TimePeak plasma concentration is achieved immediately after intravenous injection.
Duration of ActionThe duration of action is approximately 5 to 8 hours after intravenous administration, depending on the dose and patient factors.

How It Works

This medicine works by selectively blocking beta-1 adrenergic receptors located primarily in the heart. By binding to these receptors, it prevents catecholamines such as epinephrine and norepinephrine from stimulating the heart, leading to a reduction in heart rate, myocardial contractility, and cardiac conduction velocity. This results in decreased cardiac output, lowered blood pressure, and reduced myocardial oxygen demand.

Mechanism Steps

1
Binding to beta-1 receptors: This medicine binds selectively to beta-1 adrenergic receptors on cardiac myocytes and conduction tissue.
2
Inhibition of catecholamine effects: By occupying these receptors, it prevents endogenous catecholamines from exerting their stimulatory effects on the heart.
3
Reduction in heart rate and contractility: This leads to a decrease in heart rate (negative chronotropy) and myocardial contractility (negative inotropy).
4
Slowing of AV conduction: It slows conduction through the atrioventricular node, which helps control ventricular rate in atrial arrhythmias.
5
Decreased cardiac output and blood pressure: The combined effects reduce cardiac output and lower blood pressure, decreasing myocardial oxygen demand.

💡 How to Take betaloc injection 5 ml

Strength: Injection, 1 mg per ml, 5 ml vial

1This medicine is given by a healthcare professional as an intravenous injection.
2It is administered slowly over 1-2 minutes to minimize risk of hypotension.
3Continuous monitoring of heart rate, blood pressure, and ECG is required during and after administration.
4The dose may be repeated based on clinical response, as determined by the healthcare provider.
5Transition to oral therapy may be considered once the patient is stable.

Dosage Information

Adult DosageThe dosage of this medicine must be individualized by a qualified clinician based on the indication, patient's age, weight, renal and hepatic function, and clinical response. For intravenous administration, typical initial doses range from 1 to 5 mg given slowly, and may be repeated at intervals based on heart rate and blood pressure. Continuous monitoring is required. Do not self-administer.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, particularly bradycardia and hypotension. Doses should be titrated carefully, and renal function should be considered. Close monitoring is advised.
Renal ImpairmentNo specific dose adjustment is typically required for mild to moderate renal impairment. In severe renal impairment, caution is advised, and dose reduction may be necessary based on clinical response.
Hepatic ImpairmentIn patients with hepatic impairment, the metabolism of this medicine may be reduced, leading to increased plasma levels. Dose reduction and careful monitoring are recommended.
Maximum Daily DoseThe maximum daily dose for intravenous administration is not well established and depends on the clinical situation. It should not exceed the dose determined by the healthcare provider. For oral metoprolol, the maximum daily dose is typically 400 mg, but this is not applicable to the injectable form.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Alcohol
Avoid
May enhance hypotensive and sedative effects.
Grapefruit juice
Avoid
May increase metoprolol levels.

⏰ What to Do If You Miss a Dose

📌 If you miss a dose while in hospital
→ Inform your nurse or doctor immediately.
💡 They will determine if a dose is needed based on your condition.
📌 If you miss a dose at home (not applicable for injection)
→ This medicine is not for home use. Contact your healthcare provider.
💡 Do not attempt to self-administer.

⚠️ Side Effects of betaloc injection 5 ml

✅ Common Side Effects

Bradycardia (Common (5-10%))
Monitor heart rate; if symptomatic or severe, inform the healthcare provider immediately.
Hypotension (Common (5-10%))
Monitor blood pressure; if symptomatic, inform the healthcare provider.
Dizziness (Common (5-10%))
Usually resolves; avoid sudden position changes. Report if persistent.
Fatigue (Common (5-10%))
Rest if needed; report if it interferes with daily activities.
Nausea (Common (5-10%))
Usually transient; inform healthcare provider if severe or persistent.
Cold extremities (Common (5-10%))
Keep warm; report if it causes discomfort or skin changes.

🚨 Serious Side Effects

Severe bradycardia (Uncommon (0.1-1%))
Seek immediate medical attention if heart rate drops significantly or you feel faint.
Heart block (Rare (<0.1%))
Requires immediate medical intervention; monitor ECG.
Acute heart failure (Uncommon (0.1-1%))
Seek emergency care if you experience shortness of breath, swelling, or fatigue.
Bronchospasm (Rare (<0.1%))
Seek immediate medical attention if you have difficulty breathing or wheezing.
Anaphylaxis (Rare (<0.1%))
Call emergency services immediately if you experience swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Depression
Consult healthcare provider if mood changes occur.
Hallucinations
Report to healthcare provider immediately.
Thrombocytopenia
Monitor for unusual bleeding or bruising; seek medical attention if present.
Retroperitoneal fibrosis
Seek medical attention if you experience abdominal or flank pain, or decreased urine output.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Verapamil Major
Diltiazem Major
Clonidine Major
MAOIs Major
Digoxin Moderate
Amiodarone Moderate
Fluoxetine Moderate
Paroxetine Moderate
NSAIDs Moderate
Cimetidine Minor

🚨 Major Interactions

  • Verapamil
  • Diltiazem
  • Clonidine
  • Monoamine oxidase inhibitors (MAOIs)

⚡ Moderate Interactions

  • Digoxin
  • Amiodarone
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
  • NSAIDs

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering and sedative effects of this medicine, leading to increased dizziness, drowsiness, and risk of hypotension. It is advisable to avoid alcohol while receiving this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe bradycardia","Second- or third-degree heart block without a pacemaker","Cardiogenic shock","Decompensated heart failure","Severe peripheral arterial disease","Hypersensitivity to metoprolol or other beta-blockers"]

⚠️ Warnings & Precautions

["Do not abruptly discontinue; taper gradually to avoid angina exacerbation or myocardial infarction.","Use with caution in patients with bronchospastic disease; may cause bronchospasm.","May mask symptoms of hypoglycemia in diabetic patients.","May mask signs of hyperthyroidism; abrupt withdrawal can precipitate thyroid storm.","Use with caution in patients with peripheral vascular disease; may worsen symptoms.","May cause dizziness; avoid driving or operating machinery until effects are known."]

🤱 Lactation Safety

Metoprolol is excreted in breast milk in small amounts. The American Academy of Pediatrics considers it compatible with breastfeeding, but monitor the infant for bradycardia and other signs of beta-blockade. Consult a healthcare provider before breastfeeding.

💊 Overdose Management

Overdose of this medicine can cause severe bradycardia, hypotension, heart failure, bronchospasm, and hypoglycemia. Management includes supportive care, atropine for bradycardia, vasopressors for hypotension, and beta-agonists for bronchospasm. In severe cases, glucagon, high-dose insulin, and cardiac pacing may be required. Immediate medical attention is essential.

⏰ Missed Dose

This medicine is typically administered in a hospital setting by healthcare professionals. If a dose is missed, it should be administered as soon as possible if the patient is still under medical care. Do not double the dose. Follow the healthcare provider's instructions.

Additional Safety Advice

General Safety

This medicine must be administered only by a qualified healthcare professional in a hospital or clinic setting with continuous cardiac and blood pressure monitoring. Do not self-administer this injection. Inform your doctor if you have asthma, chronic obstructive pulmonary disease, diabetes, thyroid disorders, or peripheral vascular disease. Do not stop this medicine abruptly without medical advice, as it can worsen angina or precipitate a heart attack. Avoid alcohol while receiving this medicine, as it may enhance the blood pressure-lowering effect. Report any signs of slow heartbeat, severe dizziness, difficulty breathing, or swelling to your healthcare provider immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the effects of this medicine, especially bradycardia and hypotension. Doses should be titrated carefully, and renal function should be monitored. Close observation is required.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. Metoprolol is Pregnancy Category C and should be used only if clearly needed. Alternative treatments may be considered.

🏥 Post-Surgery Considerations

This medicine may be used during surgery to control heart rate and blood pressure. After surgery, monitor for bradycardia and hypotension. Transition to oral therapy may be needed.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with epinephrine used in local anesthetics, potentially causing severe hypertension or bradycardia.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce cardiac workload.
🥗
Engage in regular low-impact exercise as advised by your doctor.
😴
Monitor your heart rate and blood pressure regularly.
💧
Avoid excessive caffeine and stimulants.
🧘
Manage stress through relaxation techniques.
🌞
Get adequate sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise until your condition is stable and your doctor approves. Beta-blockers can reduce exercise tolerance and mask symptoms of overexertion. Start with light activities and gradually increase under medical guidance.

🥗 Diet Recommendations

Follow a heart-healthy diet rich in fruits, vegetables, and whole grains.
Limit sodium intake to control blood pressure.
Avoid excessive caffeine and alcohol.
Include potassium-rich foods if not contraindicated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness and fatigue, affecting your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is usually given in a hospital setting, so work life impact is minimal during acute use.

🛑 When to Stop This Medicine

Do not stop this medicine abruptly without consulting your doctor. Abrupt discontinuation can worsen angina or precipitate a heart attack. Your doctor will gradually taper the dose if needed.

📅 Long-Term Use Effects

Long-term use of metoprolol (oral) may lead to tolerance, reduced exercise tolerance, and masking of hypoglycemia symptoms in diabetics. Regular monitoring of heart rate, blood pressure, and cardiac function is recommended. Abrupt withdrawal should be avoided. The injectable form is for acute use only and not for long-term therapy.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Esmolol infusion

An ultra-short-acting beta-blocker for rapid heart rate control.

Evidence: Well-established
Labetalol injection

Combined alpha- and beta-blocker for hypertensive emergencies.

Evidence: Well-established
Calcium channel blockers (e.g., diltiazem)

Alternative for rate control in atrial fibrillation.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not store in direct sunlight

✈️ Traveling with This Medicine

This medicine is typically administered in a hospital setting and is not for self-administration during travel. If you are prescribed this medicine, ensure you have a copy of your prescription and medical records. Carry it in its original packaging with the pharmacy label. For air travel, keep it in your carry-on luggage. Check customs regulations for injectable medications. Store at room temperature and protect from light. If traveling across time zones, consult your doctor for dose adjustments.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 65-year-old man with atrial fibrillation and rapid ventricular response
He was admitted to the emergency department with a heart rate of 150 bpm and palpitations. He received this medicine intravenously under continuous monitoring. His heart rate gradually decreased to 90 bpm within 15 minutes, and his symptoms improved. He was later transitioned to oral metoprolol.
💡 Lesson: Intravenous metoprolol is effective for rapid heart rate control in atrial fibrillation, but requires close monitoring.
👤 A 50-year-old woman with hypertensive emergency
She presented with a blood pressure of 210/120 mmHg and severe headache. She was given this medicine intravenously, and her blood pressure decreased to 160/100 mmHg over 20 minutes. She was monitored for rebound hypertension and later started on oral antihypertensives.
💡 Lesson: Parenteral metoprolol can effectively lower blood pressure in hypertensive emergencies, but gradual titration and monitoring are essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 5 to 10 minutes after intravenous administration.

Q: How long does the effect last?

A: The effect typically lasts for 5 to 8 hours, but this can vary based on dose and individual factors.

Q: Can I take this medicine at home?

A: No, this medicine is for hospital use only and must be administered by a healthcare professional.

Q: What should I avoid while taking this medicine?

A: Avoid alcohol and inform your doctor about all other medications you are taking.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for betaloc injection 5 ml

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be self-administered at home.
    Fact: This medicine is an injectable prescription drug that must be given by a healthcare professional in a monitored setting.
  • Myth: This medicine is safe for everyone with high blood pressure.
    Fact: It is contraindicated in certain conditions like severe bradycardia and heart block, and must be used with caution in others.
  • Myth: You can stop this medicine abruptly without any risk.
    Fact: Abrupt discontinuation can worsen angina or cause a heart attack; it must be tapered gradually under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Metoprolol tartrate injection

Brand Alternatives

  • Betaloc injection 5 ml

📊 Comparison with Similar Medicines

[{"medicine":"Metoprolol tartrate injection","class":"Beta-1 selective blocker","route":"Intravenous","onset":"5-10 minutes","duration":"5-8 hours"},{"medicine":"Esmolol injection","class":"Beta-1 selective blocker","route":"Intravenous","onset":"1-2 minutes","duration":"10-30 minutes"},{"medicine":"Labetalol injection","class":"Alpha- and beta-blocker","route":"Intravenous","onset":"2-5 minutes","duration":"2-6 hours"}]

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