besol tablet - Betamethasone (0.5mg) medicine

Besol Tablet (Betamethasone 0.5mg) - Uses, Price, Side Effects

4.7 (15 reviews)

Betamethasone (0.5mg)

🏭 Akme Biotec 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is besol tablet used for?

Besol Tablet contains Betamethasone 0.5mg, a corticosteroid that reduces inflammation and suppresses the immune system. It is used to treat respiratory conditions like asthma and allergies, as well as inflammatory disorders. It works by blocking the release of substances that cause inflammation.

Generic Name: Betamethasone
Manufacturer: Akme Biotec
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 besol tablet Uses & Benefits

Allergic conditions, asthma, COPD exacerbations, inflammatory disorders, autoimmune diseases.

Off-label uses: COVID-19 (severe cases), certain dermatoses, cerebral edema.

📋 Drug Information

Generic Name(s)	Betamethasone
Brand Name	Alerkim
Manufacturer	Akme Biotec
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	RESPIRATORY
Action Class	Glucocorticoids
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; peak plasma concentration within 1-2 hours.

DistributionDistributes widely; crosses placenta and enters breast milk.

Protein BindingApproximately 64% bound to plasma proteins.

MetabolismHepatic via CYP3A4.

Half-Life36-54 hours (plasma); biological half-life 36-54 hours.

ExcretionRenal (primarily as metabolites) and fecal.

BioavailabilityHigh oral bioavailability (approximately 100%).

Onset of ActionWithin hours for anti-inflammatory effects.

Peak Plasma Time1-2 hours.

Duration of ActionDuration of action: 3-4 days (single dose).

How It Works

Agonist at glucocorticoid receptors, leading to anti-inflammatory and immunosuppressive effects.

Mechanism Steps

1Betamethasone binds to glucocorticoid receptor (GR) in cytoplasm.

2Receptor-ligand complex translocates to nucleus.

3Complex binds to glucocorticoid response elements (GREs) on DNA.

💡 How to Take besol tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of besol tablet

✅ Common Side Effects

Increased appetite
Weight gain
Insomnia
Mood changes
Fluid retention
Hypertension
Hyperglycemia

🚨 Serious Side Effects

Adrenal suppression
Osteoporosis
Glaucoma
Cataracts
Peptic ulcer
Pancreatitis
Psychiatric disturbances

⚠️ Rare Side Effects

Avascular necrosis
Cushing's syndrome
Growth suppression in children
Kaposi's sarcoma
Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
NSAIDs	Moderate	Increased risk of gastrointestinal bleeding
Diuretics	Moderate	Increased potassium loss
Anticoagulants	Major	Increased bleeding risk

🚨 Major Interactions

CYP3A4 inducers (e.g., rifampin, phenytoin, carbamazepine)
CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
Anticoagulants (e.g., warfarin)
NSAIDs (increased GI bleeding risk)
Antidiabetic agents (reduced efficacy)
Live vaccines (increased infection risk)

⚡ Moderate Interactions

Diuretics (increased hypokalemia risk)
Cardiac glycosides (increased toxicity risk)
Amphotericin B (increased hypokalemia)
Cholestyramine (reduced absorption)

ℹ️ Minor Interactions

Antacids (slight reduction in absorption)
Oral contraceptives (increased corticosteroid levels)

🍽️ Food Interactions

Grapefruit juice may increase levels (CYP3A4 inhibition).

🍷 Alcohol Interaction

May increase risk of GI irritation and bleeding.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Moderate

Pregnancy

Category C

🚫 Contraindications

Systemic fungal infections, hypersensitivity to betamethasone, live vaccine administration.

📊 Monitoring Parameters

Blood glucose, blood pressure, electrolytes, signs of infection, adrenal suppression.

🤱 Lactation Safety

Use with caution; excreted in breast milk.

💊 Overdose Management

Supportive care; no specific antidote; monitor electrolytes and glucose.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for besol tablet

View All

Alternative brands with exact same active ingredient (Betamethasone (0.5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026