Apriace 5mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Severe dizziness or fainting.
- Chest pain or irregular heartbeat.
- Decreased urine output or swelling in the legs.
- Yellowing of the skin or eyes, or dark urine.
- Severe abdominal pain or persistent vomiting.
- Unusual bleeding or bruising.
If experiencing severe symptoms, call emergency services immediately.
What is apriace 5mg tablet used for?
This medicine is an ACE inhibitor used to treat high blood pressure and protect kidney function in diabetes. It works by relaxing blood vessels. Take it exactly as prescribed, usually once daily. Do not use during pregnancy.
- Generic Name: Benazepril (5mg)
- Manufacturer: Nectazen Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 apriace 5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है। यह मधुमेह (डायबिटीज) वाले रोगियों में गुर्दे की रक्षा के लिए भी इस्तेमाल की जा सकती है। यह दवा हृदय पर दबाव कम करती है और स्ट्रोक तथा दिल के दौरे के जोखिम को कम करने में मदद करती है। इसे डॉक्टर के निर्देशानुसार नियमित रूप से लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान, और सूखी खांसी शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे, होंठ, जीभ या गले में सूजन आए, सांस लेने में कठिनाई हो, या बेहोशी महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से दवा की मात्रा न बदलें और न ही बंद करें। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं और रक्तचाप बहुत कम हो सकता है। पोटेशियम सप्लीमेंट या नमक के विकल्प बिना डॉक्टर की सलाह के न लें। अगर आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं, तो तुरंत डॉक्टर को बताएं। नियमित रूप से रक्तचाप, गुर्दे की कार्यप्रणाली और पोटेशियम की जांच कराते रहें।
💊 apriace 5mg tablet Uses & Benefits
[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults, reducing the risk of strokes, heart attacks, and kidney problems.","evidence":"Well-established"},{"condition":"Diabetic nephropathy","description":"This medicine may be used to protect kidney function in people with diabetes and high blood pressure.","evidence":"Well-established"},{"condition":"Heart failure","description":"This medicine may be used as part of a treatment plan for heart failure to improve symptoms and reduce hospitalizations.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Post-myocardial infarction","description":"Sometimes prescribed after a heart attack to improve survival and reduce further heart events.","evidence":"Limited"},{"condition":"Proteinuria in non-diabetic kidney disease","description":"May be used to reduce protein loss in urine in certain kidney conditions.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Diabetic nephropathy, Heart failure, Post-myocardial infarction
📋 Drug Information
| Generic Name(s) | Benazepril (5mg) |
| Brand Name | apriace 5mg tablet |
| Manufacturer | Nectazen Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Angiotensin-converting enzyme (ACE) inhibitors |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and direct sunlight. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | ACE inhibitors like benazepril are recommended by the World Health Organization as first-line treatment for hypertension in certain patient groups, especially those with diabetes or kidney disease. However, specific recommendations should be verified with current guidelines. |
| ICMR Guideline | The Indian Council of Medical Research recommends ACE inhibitors as one of the first-line options for managing hypertension in adults, particularly in patients with diabetes or kidney disease. Always consult your doctor for personalized advice. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking the action of an enzyme called angiotensin-converting enzyme (ACE). This enzyme is responsible for converting angiotensin I into angiotensin II, a powerful substance that narrows blood vessels and raises blood pressure. By blocking ACE, this medicine reduces the levels of angiotensin II, which causes blood vessels to relax and widen. This lowers blood pressure and reduces the workload on the heart. It also reduces the secretion of aldosterone, a hormone that causes the body to retain salt and water. As a result, the body loses excess salt and water, further lowering blood pressure. In the kidneys, this medicine helps to reduce pressure within the kidney filters, which can protect kidney function over time.
Mechanism Steps
💡 How to Take apriace 5mg tablet
Strength: 5 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for high blood pressure is 10 mg once daily, but your doctor may start with 5 mg if you are also taking a diuretic or are at risk of low blood pressure. The dose may be increased gradually based on your response, up to a maximum of 40 mg per day. For kidney protection in diabetes, the dose may be 10 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults may be more sensitive to the blood pressure-lowering effects of this medicine. Your doctor may start with a lower dose and monitor you closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In people with kidney problems, the dose may need to be reduced. For moderate kidney impairment, the starting dose is often 5 mg once daily. For severe kidney impairment, this medicine is not recommended. Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | In people with liver problems, this medicine should be used with caution. The dose may need to be adjusted. Dose must be individualized by a qualified clinician based on hepatic function. |
| Maximum Daily Dose | 40 mg per day. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of apriace 5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | |
| NSAIDs | Major | |
| Potassium supplements | Major | |
| Lithium | Major | |
| Diuretics | Moderate | |
| Insulin | Moderate | |
| Aliskiren | Major | |
| Antacids | Minor | |
| Capsaicin | Minor | |
| Other antihypertensives | Moderate |
🚨 Major Interactions
- Potassium supplements or potassium-sparing diuretics
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Lithium
- Aliskiren
⚡ Moderate Interactions
- Diuretics (water pills)
- Other blood pressure medicines
- Insulin and oral antidiabetic drugs
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can enhance the blood pressure-lowering effect, leading to dizziness, lightheadedness, and fainting. It may also increase the risk of liver problems.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy","History of angioedema (swelling of face, lips, throat) related to ACE inhibitors","Severe kidney problems","Bilateral renal artery stenosis","Hypersensitivity to benazepril or any ACE inhibitor","Use with aliskiren in patients with diabetes"]
⚠️ Warnings & Precautions
["This medicine can cause a dry cough. If it becomes bothersome, consult your doctor.","It can cause dizziness, especially when standing up. Rise slowly.","Avoid potassium supplements and salt substitutes containing potassium unless prescribed.","Tell your doctor if you have kidney or liver problems.","Do not use during pregnancy. Use effective contraception while taking this medicine.","Avoid alcohol while taking this medicine.","This medicine may cause low blood sugar in people with diabetes. Monitor blood sugar closely.","Seek immediate medical help if you experience swelling of the face, lips, tongue, or throat."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks.
💊 Overdose Management
If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe dizziness, fainting, and very low blood pressure. Treatment is supportive and may include intravenous fluids and close monitoring of vital signs.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor, even if you feel well. High blood pressure often has no symptoms, so you may need to take this medicine long-term. Avoid alcohol while taking this medicine, as it can increase dizziness and lower your blood pressure too much. Stand up slowly from a sitting or lying position to avoid dizziness. Tell your doctor if you have kidney problems, liver problems, diabetes, or if you are on a salt-restricted diet. Do not use potassium supplements or salt substitutes containing potassium without your doctor's approval. If you become pregnant while taking this medicine, contact your doctor immediately. Keep all your medical appointments and get your blood pressure, kidney function, and potassium levels checked regularly.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more sensitive to the blood pressure-lowering effects of this medicine. They may be at higher risk of dizziness, falls, and kidney problems. Your doctor may start with a lower dose and monitor you closely. Regular monitoring of kidney function and potassium levels is important.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning to become pregnant, talk to your doctor about safer alternatives. Use effective contraception while taking this medicine. If you become pregnant, stop taking this medicine and contact your doctor immediately.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be temporarily stopped before surgery to avoid low blood pressure during the procedure. Follow your doctor's instructions carefully.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may cause dizziness or low blood pressure during the procedure. Your dentist may take precautions. Do not stop taking this medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause dizziness, especially when you first start taking it or when the dose is increased. Avoid strenuous exercise or heavy lifting until you know how this medicine affects you. Stay hydrated during exercise. If you feel dizzy or faint, stop exercising and rest.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or tiredness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities once they adjust to the medicine. Inform your employer if your job involves operating machinery or working at heights.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as angioedema, severe dizziness, or kidney problems, contact your doctor immediately. Your doctor may switch you to a different medicine. If you become pregnant, stop taking this medicine and contact your doctor right away.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for controlling blood pressure and protecting kidney function. Regular monitoring of kidney function, potassium levels, and blood pressure is important. In some people, a persistent dry cough may develop, which may require a change in medication. Rarely, long-term use can be associated with kidney impairment or high potassium levels. Your doctor will adjust the dose as needed based on your response and kidney function.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight loss can help lower blood pressure and complement medicine.
Evidence: Well-establishedCalcium channel blockers, diuretics, or angiotensin receptor blockers (ARBs) may be alternatives if ACE inhibitors are not tolerated.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from moisture. If crossing time zones, adjust the timing of your dose gradually, but consult your doctor first. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 1 hour, but the full effect may take 1 to 2 weeks of regular use.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.
A: If you remember within 12 hours, take it. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, this medicine is not safe during pregnancy. It can harm the unborn baby. Consult your doctor for safer alternatives.
A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping can cause it to rise again.
🤔 Common Patient Concerns
🔄 Substitutes for apriace 5mg tablet
View AllAlternative brands with exact same active ingredient:
-
bampril 5 tabletAAR ESS Remedies Pvt Ltd ₹192.19 19.6% CHEAPER
-
benzil 5 tabletSolarium Pharmaceuticals ₹219.99 8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure high blood pressure.
Fact: This medicine controls high blood pressure but does not cure it. You may need to take it long-term. - Myth: You can stop taking this medicine once your blood pressure is normal.
Fact: High blood pressure often has no symptoms. Stopping the medicine can cause your blood pressure to rise again. Always consult your doctor before stopping. - Myth: This medicine causes kidney damage.
Fact: This medicine actually protects kidney function in many people, especially those with diabetes. Regular monitoring is important.
🔄 Alternative Options
Generic Alternatives
- Benazepril 5 mg tablet
Brand Alternatives
- Lotensin
- Cibacen
- Benazepril