beniduce 4mg tablet

4.6 (20 reviews)

Benidipine (4mg)

🏭 Macleods Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is beniduce 4mg tablet used for?

Benitowa 4 Tablet (Benidipine) is used to treat CARDIAC. It contains Benidipine (4mg), which Blocks voltage-dependent L-type calcium channels, inhibiting calcium influx into. Always consult your doctor before use. Take as prescribed.

Generic Name: Benidipine
Manufacturer: Macleods Pharmaceuticals Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 beniduce 4mg tablet Uses & Benefits

Hypertension, angina pectoris

Off-label uses: Raynaud's phenomenon, chronic kidney disease

📋 Drug Information

Generic Name(s)	Benidipine
Brand Name	Benitowa 4 Tablet
Manufacturer	Macleods Pharmaceuticals Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	CARDIAC
Action Class	Calcium channel blockers- Dihydropyridines (DHP)
Route of Administration	Oral
Storage	Store at room temperature (20-25°C), protect from light and moisture
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration

DistributionWidely distributed; high affinity for vascular smooth muscle

Protein Binding>99%

MetabolismHepatic via CYP3A4

Half-Life20-30 hours

ExcretionFecal (60%) and renal (40%)

BioavailabilityApproximately 10-20% due to first-pass metabolism

Onset of Action1-2 hours

Peak Plasma Time2-4 hours

Duration of Action24 hours

How It Works

Blocks voltage-dependent L-type calcium channels, inhibiting calcium influx into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure.

Mechanism Steps

1Benidipine binds to L-type calcium channels on vascular smooth muscle and cardiac muscle cells.

2Inhibition of calcium influx prevents calcium-dependent contraction.

3Vascular smooth muscle relaxation leads to vasodilation and decreased peripheral vascular resistance.

💡 How to Take beniduce 4mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of beniduce 4mg tablet

✅ Common Side Effects

Headache
Dizziness
Flushing
Peripheral edema
Palpitations

🚨 Serious Side Effects

Severe hypotension
Angina exacerbation
Hepatotoxicity
Stevens-Johnson syndrome

⚠️ Rare Side Effects

Gingival hyperplasia
Gynecomastia
Leukopenia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Ketoconazole	Major	Increased benidipine plasma concentration
Rifampin	Major	Decreased benidipine efficacy
Grapefruit juice	Moderate	Increased benidipine levels
Beta-blockers	Moderate	Additive bradycardia and hypotension
Digoxin	Moderate	Increased digoxin levels
Cimetidine	Minor	Slight increase in benidipine levels
Antacids	Minor	Reduced absorption of benidipine

🚨 Major Interactions

CYP3A4 inhibitors (e.g., ketoconazole, itraconazole)
CYP3A4 inducers (e.g., rifampin, phenytoin)
Other antihypertensives (additive effect)

⚡ Moderate Interactions

Grapefruit juice
Beta-blockers
Digoxin

ℹ️ Minor Interactions

Cimetidine
Antacids

🍽️ Food Interactions

Grapefruit juice increases plasma concentration; avoid concurrent use.

🍷 Alcohol Interaction

May enhance hypotensive effect; avoid excessive alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to benidipine or dihydropyridines, severe hypotension, cardiogenic shock, unstable angina, acute myocardial infarction

📊 Monitoring Parameters

Blood pressure, heart rate, liver function tests, renal function

🤱 Lactation Safety

Not recommended; excreted in breast milk

💊 Overdose Management

Symptomatic and supportive; monitor blood pressure and heart rate; administer vasopressors if needed

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for beniduce 4mg tablet

View All

Alternative brands with exact same active ingredient (Benidipine (4mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.