Benfotor Injection - Uses, Price, Side Effects & Dosage
What is benfotor injection used for?
Benfotor Injection is a combination of Methylcobalamin (1000mcg) and Vitamin B6 (Pyridoxine 100mg) used to treat nerve disorders and vitamin B deficiencies. Methylcobalamin helps regenerate nerves and improve nerve function, while Vitamin B6 supports neurotransmitter synthesis. It is commonly prescribed for peripheral neuropathy, diabetic neuropathy, and neuralgias. The injection is administered intramuscularly or intravenously as directed by a physician.
- Generic Name: Methylcobalamin + Vitamin B6 (Pyridoxine)
- Manufacturer: Cnscure India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ benfotor injection Uses & Benefits
Peripheral neuropathy, megaloblastic anemia, homocysteinemia, vitamin B12 and B6 deficiency.
Off-label uses: Chronic fatigue syndrome, diabetic neuropathy, carpal tunnel syndrome.
๐ Drug Information
| Generic Name(s) | Methylcobalamin + Vitamin B6 (Pyridoxine) |
| Brand Name | Alnacob Plus Injection |
| Manufacturer | Cnscure India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Vitamins/Minerals/Nutrients |
| Route of Administration | Intramuscular injection |
| Storage | Store at 2-8ยฐC, protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Methylcobalamin acts as a cofactor for methionine synthase, essential for myelin synthesis; Pyridoxine is a cofactor for enzymes in neurotransmitter synthesis and homocysteine metabolism.
Mechanism Steps
๐ก How to Take benfotor injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of benfotor injection
โ Common Side Effects
- Injection site pain
- Mild diarrhea
- Headache
๐จ Serious Side Effects
- Anaphylaxis
- Peripheral neuropathy (with high dose pyridoxine)
- Thrombotic events
โ ๏ธ Rare Side Effects
- Acne
- Photosensitivity
- Hypersensitivity reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Levodopa | Major | Pyridoxine reduces levodopa efficacy by increasing peripheral metabolism. |
| Chloramphenicol | Major | May impair response to vitamin B12 therapy. |
| Colchicine | Major | May decrease absorption of vitamin B12. |
| Phenytoin | Moderate | Pyridoxine may decrease phenytoin levels. |
| Oral contraceptives | Moderate | May increase requirement for pyridoxine. |
| Isoniazid | Moderate | May cause pyridoxine deficiency. |
| Penicillamine | Minor | May increase pyridoxine requirement. |
| Cycloserine | Minor | May increase pyridoxine requirement. |
๐จ Major Interactions
- Levodopa
- Chloramphenicol
- Colchicine
โก Moderate Interactions
- Anticonvulsants (phenytoin, phenobarbital)
- Oral contraceptives
- Isoniazid
โน๏ธ Minor Interactions
- Penicillamine
- Cycloserine
๐ฝ๏ธ Food Interactions
None significant
๐ท Alcohol Interaction
Chronic alcohol use may reduce absorption of vitamin B6.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component; severe renal impairment (for high doses of pyridoxine).
๐ Monitoring Parameters
Serum vitamin B12 and B6 levels, homocysteine levels, neurological examination.
๐คฑ Lactation Safety
Safe; both vitamins are excreted in breast milk but not harmful.
๐ Overdose Management
Discontinue injection; symptomatic treatment; pyridoxine overdose may cause neuropathy.
โฐ Missed Dose
Administer as soon as remembered; if close to next dose, skip missed dose.