bemol p 50mg/500mg tablet - Diclofenac (50mg) + Paracetamol (500mg) medicine

Diclofenac Sodium & Paracetamol 50mg/500mg Tablet: Complete Information

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🏭 Brooks Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term pain relief.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is bemol p 50mg/500mg tablet used for?

This medicine is a combination of Diclofenac Sodium 50 mg and Paracetamol 500 mg used for short-term relief of acute pain and inflammation. It works by reducing prostaglandins that cause pain. Take it with food, do not exceed 3 tablets in 24 hours, and avoid alcohol.

  • Generic Name: Diclofenac (50mg) + Paracetamol (500mg)
  • Manufacturer: Brooks Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 bemol p 50mg/500mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डाइक्लोफेनाक सोडियम 50 मिलीग्राम और पैरासिटामोल 500 मिलीग्राम का संयोजन है। इसका उपयोग तीव्र दर्द और सूजन जैसे मांसपेशियों के दर्द, जोड़ों के दर्द, दांत दर्द, मासिक धर्म के दर्द और सर्जरी के बाद के दर्द के लिए किया जाता है। यह दवा सूजन पैदा करने वाले प्रोस्टाग्लैंडिन को कम करके काम करती है। इसे भोजन के साथ लें और 24 घंटे में 3 गोलियों से अधिक न लें। शराब का सेवन न करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, एलर्जी प्रतिक्रिया, गुर्दे की समस्या, यकृत की क्षति और हृदय संबंधी घटनाएं शामिल हैं। यदि आपको काला मल, खून की उल्टी, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या पेशाब में कमी जैसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को हमेशा भोजन या दूध के साथ लें ताकि पेट में जलन न हो। निर्धारित खुराक से अधिक न लें। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव और यकृत की क्षति का खतरा बढ़ जाता है। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको गुर्दे, यकृत, या हृदय की समस्या है, तो डॉक्टर से परामर्श लें। चक्कर आ सकते हैं, इसलिए वाहन चलाने से बचें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 bemol p 50mg/500mg tablet Uses & Benefits

[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and back pain.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after surgical procedures.","evidence":"Well-established"},{"condition":"Dental pain","description":"Effective for relief of toothache and pain following dental extraction.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Provides symptomatic relief of pain and stiffness in osteoarthritis, but only for short-term use.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"May be used for short-term relief of pain and inflammation in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Renal colic","description":"May be used off-label for pain relief in kidney stones, but requires medical supervision.","evidence":"Limited"}]

Primary treatment for: Acute pain and inflammation

Also treats: Osteoarthritis, Rheumatoid arthritis, Dysmenorrhea, Post-operative pain, Dental pain

📋 Drug Information

Generic Name(s)Diclofenac (50mg) + Paracetamol (500mg)
Brand Namebemol p 50mg/500mg tablet
ManufacturerBrooks Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce stomach upset.
2
Do not exceed 3 tablets in 24 hours.
3
Avoid alcohol completely while taking this medicine.
4
Do not combine with other NSAIDs or paracetamol-containing products.
5
Consult your doctor if pain persists beyond 7 days or worsens.
6
Report any signs of bleeding, such as black stools or easy bruising, immediately.
7
Stay well hydrated throughout the day.
8
Use the lowest effective dose for the shortest duration possible.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Acute joint pain
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine contains paracetamol which reduces fever, but it is not a primary fever reducer.
Not Primary
Chronic pain
Not recommended for long-term use without medical supervision.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDiclofenac is rapidly absorbed from the gastrointestinal tract after oral administration, with peak plasma concentrations occurring within 1-2 hours. Paracetamol is also rapidly and completely absorbed from the gastrointestinal tract, with peak plasma concentrations within 0.5-2 hours. Food may delay the absorption of both drugs but does not significantly reduce the extent of absorption.
DistributionDiclofenac is highly bound to plasma proteins (approximately 99%) and distributes widely into tissues, including synovial fluid. Paracetamol has a volume of distribution of approximately 0.9 L/kg and distributes throughout most body tissues. Both drugs cross the placenta and are excreted in breast milk in small amounts.
Protein BindingDiclofenac: approximately 99% bound to plasma proteins, primarily albumin. Paracetamol: approximately 10-25% bound to plasma proteins.
MetabolismDiclofenac is metabolized in the liver by cytochrome P450 enzymes, primarily CYP2C9, to several metabolites, including 4'-hydroxydiclofenac. Paracetamol is metabolized in the liver primarily by glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to the toxic intermediate N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified by glutathione.
Half-LifeDiclofenac: approximately 1-2 hours. Paracetamol: approximately 2-3 hours.
ExcretionDiclofenac is excreted mainly in urine (approximately 65%) and bile (approximately 35%) as metabolites. Paracetamol is excreted in urine as glucuronide and sulfate conjugates, with less than 5% excreted unchanged.
BioavailabilityDiclofenac: approximately 50-60% due to first-pass metabolism. Paracetamol: approximately 80-90%.
Onset of ActionPain relief typically begins within 30-60 minutes after oral administration.
Peak Plasma TimeDiclofenac: 1-2 hours. Paracetamol: 0.5-2 hours.
Duration of ActionPain relief lasts approximately 4-6 hours, requiring dosing every 6-8 hours as needed.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Diclofenac Sodium is a non-steroidal anti-inflammatory drug that reversibly inhibits both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, leading to decreased synthesis of prostaglandins, prostacyclin, and thromboxane. This results in reduced inflammation, pain, and fever. Paracetamol (acetaminophen) acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, producing analgesia and antipyresis with minimal anti-inflammatory effects. The combination provides enhanced pain relief through different pathways.

Mechanism Steps

1
Diclofenac inhibits COX enzymes: Diclofenac binds reversibly to the active site of cyclooxygenase-1 and cyclooxygenase-2 enzymes, blocking the conversion of arachidonic acid to prostaglandin H2.
2
Reduced prostaglandin synthesis: This leads to decreased production of prostaglandins, prostacyclin, and thromboxane, which are mediators of pain, inflammation, and fever.
3
Paracetamol acts centrally: Paracetamol inhibits prostaglandin synthesis in the central nervous system and may activate descending inhibitory pathways, reducing pain perception.
4
Combined analgesic effect: The combination of peripheral anti-inflammatory action and central analgesic action results in enhanced pain relief compared to either agent alone.

💡 How to Take bemol p 50mg/500mg tablet

Strength: Tablet containing Diclofenac Sodium 50 mg and Paracetamol 500 mg.

1Take this medicine orally with a full glass of water.
2Take with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow the prescribed dose and duration exactly.
5Do not take more than 3 tablets in 24 hours.
6If you miss a dose, take it as soon as you remember unless it is almost time for the next dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet (Diclofenac Sodium 50 mg + Paracetamol 500 mg) taken orally every 6 to 8 hours as needed for pain relief, not exceeding 3 tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration. Take with food or milk to reduce stomach upset.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration possible. Consult a doctor for appropriate dosing.
Renal ImpairmentUse with caution in patients with renal impairment. Dose reduction may be necessary. Avoid use in severe renal impairment (eGFR <30 mL/min). Consult a doctor for appropriate dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction may be necessary. Avoid use in severe hepatic impairment. Consult a doctor for appropriate dosing.
Maximum Daily DoseMaximum daily dose: 3 tablets (Diclofenac Sodium 150 mg + Paracetamol 1500 mg) in 24 hours. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding and liver damage.
Caffeine
Limit excessive intake
May increase stomach irritation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of bemol p 50mg/500mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce nausea. If persistent, consult your doctor.
Stomach pain or indigestion (Common (5-10%))
Take with food. Avoid alcohol. If severe, contact your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Avoid activities requiring alertness. Consult doctor if excessive.

🚨 Serious Side Effects

Gastrointestinal bleeding or ulceration (Rare (<0.1%))
Seek immediate medical attention if you notice black or tarry stools, vomiting blood, or severe abdominal pain.
Allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, or throat, difficulty breathing, or severe rash.
Kidney impairment (Rare (<0.1%))
Report decreased urine output, swelling in legs, or fatigue to your doctor immediately.
Liver damage (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or persistent nausea.
Cardiovascular events (heart attack, stroke) (Rare (<0.1%))
Call emergency services if you experience chest pain, shortness of breath, or sudden weakness.

⚠️ Rare Side Effects

Blood disorders (e.g., thrombocytopenia, leukopenia)
Report unusual bruising or bleeding to your doctor.
Severe skin reactions (e.g., Stevens-Johnson syndrome)
Seek immediate medical attention if you develop a rash with blisters or peeling skin.
Aseptic meningitis
Seek immediate medical attention if you experience severe headache, stiff neck, and fever.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Methotrexate Major
ACE inhibitors Major
Diuretics Major
Corticosteroids Moderate
SSRIs Moderate
Lithium Moderate
Cyclosporine Moderate
Digoxin Moderate

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., ibuprofen, aspirin)
  • Methotrexate
  • ACE inhibitors and angiotensin receptor blockers
  • Diuretics

⚡ Moderate Interactions

  • Corticosteroids
  • Selective serotonin reuptake inhibitors (SSRIs)
  • Lithium
  • Cyclosporine
  • Digoxin

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver damage, especially with paracetamol. It may also enhance the central nervous system effects such as dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to diclofenac, paracetamol, or any NSAID","History of asthma, urticaria, or allergic reaction to aspirin or other NSAIDs","Active or history of peptic ulcer or gastrointestinal bleeding","Severe heart failure, ischemic heart disease, peripheral arterial disease, and/or cerebrovascular disease","Severe hepatic impairment or active liver disease","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Take with food or milk to reduce gastrointestinal irritation.","Avoid alcohol consumption.","Do not exceed recommended dose or duration.","Use with caution in elderly patients due to increased risk of side effects.","Use with caution in patients with dehydration, kidney disease, or heart failure.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use concurrently with other NSAIDs or paracetamol-containing products.","Consult doctor if symptoms persist beyond 7 days or worsen."]

🤱 Lactation Safety

Diclofenac and paracetamol are excreted in breast milk in small amounts. Short-term use is generally considered compatible with breastfeeding, but consult your doctor before use.

💊 Overdose Management

Overdose of this medicine can cause severe liver damage due to paracetamol and gastrointestinal bleeding, kidney failure, and central nervous system effects due to diclofenac. Seek immediate medical attention. Treatment includes activated charcoal if within 1-2 hours, N-acetylcysteine for paracetamol toxicity, and supportive care. Do not induce vomiting unless instructed by a healthcare professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Always take this medicine with food or milk to reduce stomach upset. Do not exceed the recommended dose or duration of treatment. Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding and liver damage. Do not take other NSAIDs or paracetamol-containing products simultaneously to prevent overdose. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, asthma, or bleeding disorders. This medicine may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Store at room temperature away from moisture and heat. Do not use after the expiry date. If you miss a dose, take it as soon as you remember unless it is almost time for the next dose; do not double the dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney function and blood pressure regularly.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning pregnancy. Diclofenac is generally avoided in the third trimester. Paracetamol is considered relatively safe but should be used at the lowest effective dose for the shortest duration.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain, but it can increase the risk of bleeding. Inform your surgeon if you are taking this medicine before surgery. It may need to be stopped before certain procedures.

🦷 Dental Procedures

This medicine can be used for dental pain, but inform your dentist if you are taking it before any dental procedure, as it may increase bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Stay hydrated.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may increase pain while taking this medicine. Gentle stretching and low-impact exercises are generally safe. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce processed food intake.
Stay well hydrated.
Avoid alcohol.
Eat a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset, so take it with food. Generally, it does not significantly impact desk work.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or kidney problems. Do not stop abruptly if you are on long-term therapy without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, liver damage, and cardiovascular events. It is not recommended for chronic use without regular monitoring. If long-term therapy is necessary, your doctor may monitor liver and kidney function, blood counts, and blood pressure. Use the lowest effective dose for the shortest duration possible.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Hot/cold compresses

May help relieve localized pain and inflammation.

Evidence: Limited
Acupuncture

Some evidence for pain relief in certain conditions.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature, away from direct sunlight and moisture. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying prescription medicines. Do not leave it in a hot car.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 30-year-old woman with severe menstrual cramps
Used this medicine for dysmenorrhea. Experienced relief within 45 minutes. Was advised not to exceed 3 tablets per day and to avoid alcohol.
💡 Lesson: Short-term use as needed provides effective relief, but exceeding the dose can cause serious side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30-60 minutes after taking it orally.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce the risk of stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take with other NSAIDs or paracetamol-containing products without consulting your doctor, as it can increase the risk of side effects.

Q: How many tablets can I take in a day?

A: Do not exceed 3 tablets in 24 hours unless directed by your doctor.

Q: Can I drink alcohol while taking this medicine?

A: No, alcohol should be avoided as it increases the risk of stomach bleeding and liver damage.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for bemol p 50mg/500mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is safe for long-term use.
    Fact: It is intended for short-term use only. Long-term use increases the risk of gastrointestinal, cardiovascular, and kidney side effects.
  • Myth: It can be taken on an empty stomach.
    Fact: It should be taken with food or milk to reduce stomach upset.
  • Myth: It is safe to take with alcohol.
    Fact: Alcohol increases the risk of stomach bleeding and liver damage. Avoid alcohol.
  • Myth: It can be combined with other painkillers.
    Fact: Combining with other NSAIDs or paracetamol can lead to overdose and serious side effects. Consult your doctor.

🔄 Alternative Options

Generic Alternatives

  • Diclofenac Sodium 50 mg + Paracetamol 500 mg Tablet (various manufacturers)

Brand Alternatives

  • Blue Cross Laboratories Ltd's Diclofenac Sodium & Paracetamol 50mg/500mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Diclofenac Sodium & Paracetamol 50mg/500mg Tablet","composition":"Diclofenac 50 mg + Paracetamol 500 mg","onset":"30-60 minutes","duration":"4-6 hours","common_use":"Acute pain and inflammation"},{"medicine":"Aceclofenac 100 mg + Paracetamol 325 mg Tablet","composition":"Aceclofenac 100 mg + Paracetamol 325 mg","onset":"30-60 minutes","duration":"4-6 hours","common_use":"Acute pain and inflammation"},{"medicine":"Ibuprofen 400 mg + Paracetamol 500 mg Tablet","composition":"Ibuprofen 400 mg + Paracetamol 500 mg","onset":"30-60 minutes","duration":"4-6 hours","common_use":"Acute pain and inflammation"}]

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