bdsure 3.75mg injection

4.5 (13 reviews)

Leuprolide (3.75mg)

🏭 BDR Pharmaceuticals Internationals Pvt 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is bdsure 3.75mg injection used for?

Agopride Injection (Leuprolide) is used to treat GYNAECOLOGICAL. It contains Leuprolide (3.75mg), which GnRH agonist; continuous stimulation downregulates pituitary GnRH receptors, red. Always consult your doctor before use. Take as prescribed.

Generic Name: Leuprolide
Manufacturer: BDR Pharmaceuticals Internationals Pvt
Form: Allopathy
Pregnancy Category: X
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 bdsure 3.75mg injection Uses & Benefits

Endometriosis, uterine fibroids, central precocious puberty, prostate cancer (male), assisted reproduction

Off-label uses: Breast cancer, transgender hormone therapy, hirsutism

📋 Drug Information

Generic Name(s)	Leuprolide
Brand Name	Agopride Injection
Manufacturer	BDR Pharmaceuticals Internationals Pvt
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	GYNAECOLOGICAL
Action Class	GNRH agonists/analogue
Route of Administration	Subcutaneous or intramuscular injection
Storage	Store at 20-25°C; protect from light
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after subcutaneous or intramuscular injection

DistributionDistributes widely; volume of distribution ~27 L

Protein Binding~43-49% bound to plasma proteins

MetabolismMetabolized primarily by peptidases; not significantly hepatic

Half-Life~3 hours (single dose); prolonged with depot formulations

ExcretionRenal (primarily as metabolites)

Bioavailability~90% after subcutaneous injection

Onset of ActionInitial flare (1-2 weeks) then suppression (2-4 weeks)

Peak Plasma Time1-2 hours after injection

Duration of Action1 month (depot formulation)

How It Works

GnRH agonist; continuous stimulation downregulates pituitary GnRH receptors, reducing LH and FSH secretion, thereby suppressing gonadal steroid production

Mechanism Steps

1Binds to GnRH receptors on pituitary gonadotropes

2Initial stimulation causes LH and FSH release (flare effect)

3Continuous exposure desensitizes receptors

💡 How to Take bdsure 3.75mg injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of bdsure 3.75mg injection

✅ Common Side Effects

Hot flashes
Sweating
Headache
Nausea
Injection site reactions
Vaginal dryness
Decreased libido

🚨 Serious Side Effects

Anaphylaxis
Seizures
Pituitary apoplexy
Spinal cord compression
QT prolongation

⚠️ Rare Side Effects

Osteoporosis
Hyperglycemia
Depression
Thromboembolism

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Estrogen-containing medications	Major	May counteract therapeutic effect
Progestins	Major	May counteract therapeutic effect
Gonadotropins	Major	May interfere with ovulation induction
Antidiabetic agents	Moderate	May alter glucose metabolism
Corticosteroids	Moderate	May increase risk of bone loss
Anticoagulants	Moderate	May increase bleeding risk

🚨 Major Interactions

Estrogen-containing medications
Progestins
Gonadotropins

⚡ Moderate Interactions

Antidiabetic agents
Corticosteroids
Anticoagulants

ℹ️ Minor Interactions

None significant

🍽️ Food Interactions

None known

🍷 Alcohol Interaction

No known interaction

🛡️ Safety & Warnings

🚫 Contraindications

Pregnancy, lactation, undiagnosed vaginal bleeding, hypersensitivity to GnRH agonists

📊 Monitoring Parameters

Hormone levels (LH, FSH, estradiol/testosterone), bone density, lipid profile, blood glucose

🤱 Lactation Safety

Not recommended; may suppress lactation

💊 Overdose Management

Supportive care; no specific antidote

⏰ Missed Dose

Administer as soon as remembered; do not double dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for bdsure 3.75mg injection

View All

Alternative brands with exact same active ingredient (Leuprolide (3.75mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026