bdpoma capsule - Uses, Price, Side Effects & Substitutes
What is bdpoma capsule used for?
Bdpoma Capsule (Pomalidomide) is used to treat ANTI NEOPLASTICS. It contains Pomalidomide (4mg), which Pomalidomide is an immunomodulatory agent with antineoplastic activity. It inhib. Always consult your doctor before use. Take as prescribed.
- Generic Name: Pomalidomide
- Manufacturer: BDR Pharmaceuticals Internationals Pvt
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bdpoma capsule Uses & Benefits
Multiple myeloma (relapsed/refractory) in combination with dexamethasone after at least two prior therapies including lenalidomide and a proteasome inhibitor.
Off-label uses: Myelofibrosis, systemic sclerosis, graft-versus-host disease (investigational).
๐ Drug Information
| Generic Name(s) | Pomalidomide |
| Brand Name | Bdpoma Capsule |
| Manufacturer | BDR Pharmaceuticals Internationals Pvt |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Immunomodulatory derivatives of thalidomide |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Pomalidomide is an immunomodulatory agent with antineoplastic activity. It inhibits proliferation and induces apoptosis of multiple myeloma cells, enhances T-cell and natural killer (NK) cell-mediated immunity, and inhibits angiogenesis.
Mechanism Steps
๐ก How to Take bdpoma capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bdpoma capsule
โ Common Side Effects
- Fatigue
- Anemia
- Neutropenia
- Thrombocytopenia
- Constipation
- Diarrhea
- Nausea
- Dyspnea
- Pyrexia
- Peripheral edema
๐จ Serious Side Effects
- Deep vein thrombosis
- Pulmonary embolism
- Severe neutropenia
- Febrile neutropenia
- Hepatotoxicity
- Tumor lysis syndrome
- Severe skin reactions (e.g., Stevens-Johnson syndrome)
โ ๏ธ Rare Side Effects
- QT prolongation
- Interstitial lung disease
- Progressive multifocal leukoencephalopathy (PML)
- Secondary malignancies
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Fluvoxamine | Major | Increased pomalidomide exposure; risk of toxicity. |
| Ciprofloxacin | Major | Increased pomalidomide exposure; risk of toxicity. |
| Ketoconazole | Major | Increased pomalidomide exposure; risk of toxicity. |
| Rifampin | Major | Decreased pomalidomide exposure; reduced efficacy. |
| Warfarin | Moderate | Increased INR; monitor closely. |
| Digoxin | Moderate | Increased digoxin levels; monitor. |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy; use additional methods. |
๐จ Major Interactions
- CYP1A2 inhibitors (e.g., fluvoxamine, ciprofloxacin)
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- CYP1A2 inducers (e.g., smoking, omeprazole)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
โก Moderate Interactions
- Warfarin
- Digoxin
- Oral contraceptives
โน๏ธ Minor Interactions
- Antacids
- H2 receptor antagonists
๐ฝ๏ธ Food Interactions
Avoid grapefruit juice (CYP3A4 inhibitor); high-fat meals may reduce absorption.
๐ท Alcohol Interaction
Avoid alcohol; may increase risk of hepatotoxicity and dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Pregnancy, hypersensitivity to pomalidomide or lenalidomide, women of childbearing potential not using effective contraception.
๐ Monitoring Parameters
Complete blood count (CBC) weekly for first 8 weeks, then monthly; liver function tests; renal function; pregnancy test (if applicable); ECG if risk of QT prolongation.
๐คฑ Lactation Safety
Not recommended; unknown if excreted in human milk.
๐ Overdose Management
No specific antidote; supportive care; monitor for adverse effects.
โฐ Missed Dose
If missed, take as soon as remembered unless next dose is within 12 hours; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for bdpoma capsule
View AllAlternative brands with exact same active ingredient (Pomalidomide (4mg)):
-
pomalong 4mg capsuleCipla Ltd โน11,250.00 166.7% COSTLIER
-
pomyelo 4mg tabletIntas Pharmaceuticals Ltd โน14,817.39 251.2% COSTLIER
-
pomalid 4mg capsuleNatco Pharma Ltd โน14,949.00 254.3% COSTLIER
-
pomired 4mg capsuleDr Reddy's Laboratories Ltd โน15,019.69 256% COSTLIER
-
pomavia 4mg capsuleLupin Ltd โน16,432.00 289.5% COSTLIER
-
pomahope 4mg capsuleAbbott โน16,833.51 299% COSTLIER
-
myhb 4mg tabletMylan Pharmaceuticals Pvt Ltd โน18,750.00 344.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.