b-nac 75mg injection - Diclofenac (75mg/3 ml) medicine

b-nac 75mg Injection: Complete Medicine Guide

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🏭 Elfin Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Diclofenac is generally avoided during the third trimester due to risk of premature closure of the ductus arteriosus. Use in pregnancy should be based on a careful risk-benefit assessment by a clinician. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for acute pain and inflammation.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding
  • Severe dizziness or fainting

If experiencing severe symptoms, call emergency services immediately.

What is b-nac 75mg injection used for?

This medicine is a diclofenac injection used for short-term relief of moderate to severe acute pain and inflammation. It works by blocking COX enzymes to reduce prostaglandins. It is given by a healthcare professional as an intramuscular injection, usually 75 mg once daily, with a maximum of 150 mg per day. It is not for self-administration.

  • Generic Name: Diclofenac
  • Manufacturer: Elfin Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 b-nac 75mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा डाइक्लोफेनाक का इंजेक्शन है, जिसका उपयोग मध्यम से गंभीर तीव्र दर्द और सूजन के इलाज के लिए किया जाता है। यह आमतौर पर मांसपेशियों में गहरे इंजेक्शन के रूप में दी जाती है। यह दर्द, सूजन और बुखार को कम करने में मदद करती है। यह दवा ऑस्टियोआर्थराइटिस, रूमेटाइड आर्थराइटिस, गुर्दे की पथरी के दर्द, और सर्जरी के बाद के दर्द के लिए दी जाती है। यह दवा केवल डॉक्टर या स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, मतली, उल्टी, दस्त, कब्ज, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, दिल का दौरा, स्ट्रोक, गुर्दे की समस्या, लीवर की समस्या, और गंभीर एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं।

सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों के बारे में बताएं, खासकर यदि आपको पेट के अल्सर, हृदय रोग, गुर्दे या लीवर की समस्या, या अस्थमा है। यदि आपको डाइक्लोफेनाक या अन्य NSAIDs से एलर्जी है तो इस दवा का उपयोग न करें। इस दवा के साथ शराब का सेवन न करें। यदि आपको चक्कर आना या नींद आना महसूस हो तो वाहन न चलाएं। किसी भी असामान्य रक्तस्राव, गंभीर पेट दर्द, सीने में दर्द, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर को बताएं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 b-nac 75mg injection Uses & Benefits

[{"condition":"Acute musculoskeletal pain","description":"Provides rapid relief from moderate to severe pain associated with muscle strains, sprains, and soft tissue injuries.","evidence":"Well-established"},{"condition":"Postoperative pain","description":"Used for short-term management of pain following surgical procedures when oral intake is not possible.","evidence":"Well-established"},{"condition":"Renal colic","description":"Effective in relieving the severe pain of kidney stones by reducing inflammation and spasms.","evidence":"Well-established"},{"condition":"Acute exacerbation of osteoarthritis or rheumatoid arthritis","description":"Provides rapid symptomatic relief during flare-ups when oral therapy is inadequate.","evidence":"Well-established"},{"condition":"Acute gout","description":"Helps reduce pain and inflammation during acute gouty attacks.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, though not first-line.","evidence":"Limited"},{"condition":"Biliary colic","description":"May be used off-label for pain relief in biliary colic.","evidence":"Limited"}]

Primary treatment for: Acute pain and inflammation

Also treats: Osteoarthritis, Rheumatoid arthritis, Renal colic, Postoperative pain, Acute gout

📋 Drug Information

Generic Name(s)Diclofenac
Brand NameAdiflam 50mg Tablet
ManufacturerElfin Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
Route of AdministrationParenteral (intramuscular injection)
StorageStore below 30°C in a dry place, protected from light. Do not freeze. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine by deep intramuscular injection into the gluteal region to minimize local irritation.
2
Use the lowest effective dose for the shortest duration to reduce the risk of cardiovascular and gastrointestinal side effects.
3
Assess renal and hepatic function before initiating therapy, especially in elderly or debilitated patients.
4
Avoid concomitant use with other NSAIDs, including aspirin, to prevent additive toxicity.
5
Consider gastroprotection with a proton pump inhibitor in patients at high risk of gastrointestinal bleeding.
6
Monitor for signs of bleeding, especially in patients on anticoagulants or with bleeding disorders.
7
Instruct patients to avoid alcohol and to report any unusual symptoms immediately.
8
Do not use this medicine for perioperative pain in coronary artery bypass graft surgery.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing intramuscular injection, diclofenac is rapidly and completely absorbed. The bioavailability is approximately 90% compared to oral administration. Peak plasma concentrations are achieved within 10 to 30 minutes after injection.
DistributionDiclofenac is highly bound to plasma proteins and distributes extensively into synovial fluid, where it can persist for up to 12 hours. It crosses the placenta and is excreted in breast milk in small amounts.
Protein BindingGreater than 99% bound to plasma proteins, primarily albumin.
MetabolismDiclofenac is metabolized in the liver by cytochrome P450 enzymes, primarily CYP2C9, into several metabolites, including 4'-hydroxydiclofenac, 5'-hydroxydiclofenac, and 3'-hydroxydiclofenac. Some metabolites may have weak pharmacological activity.
Half-LifeThe terminal elimination half-life is approximately 1 to 2 hours. However, the synovial fluid half-life is about 3 to 6 hours.
ExcretionDiclofenac and its metabolites are excreted primarily in the urine (about 65%) and bile/feces (about 35%).
BioavailabilityApproximately 90% following intramuscular injection.
Onset of ActionPain relief typically begins within 10 to 30 minutes after intramuscular injection.
Peak Plasma TimePeak plasma concentration occurs within 10 to 30 minutes after intramuscular administration.
Duration of ActionThe analgesic effect usually lasts 4 to 6 hours, but can be longer depending on the indication and individual factors.

How It Works

This medicine works by reversibly inhibiting both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, which are responsible for converting arachidonic acid into prostaglandins and thromboxanes. By blocking these enzymes, it reduces the production of prostaglandins, which are key mediators of pain, inflammation, and fever. The anti-inflammatory effect is primarily due to inhibition of COX-2, while the gastrointestinal and platelet effects are largely due to COX-1 inhibition.

Mechanism Steps

1
Inhibition of cyclooxygenase enzymes: This medicine binds to and reversibly inhibits the COX-1 and COX-2 enzymes in the arachidonic acid pathway.
2
Reduced prostaglandin synthesis: By inhibiting COX enzymes, the conversion of arachidonic acid to prostaglandin H2 is blocked, leading to decreased production of prostaglandins and thromboxanes.
3
Decreased pain and inflammation: Lower levels of prostaglandins result in reduced sensitization of pain receptors, decreased vasodilation, and less edema at sites of inflammation.
4
Antipyretic effect: Prostaglandin E2 in the hypothalamus is reduced, leading to lowering of elevated body temperature.
5
Platelet inhibition: Inhibition of COX-1 in platelets reduces thromboxane A2 production, impairing platelet aggregation and prolonging bleeding time.

💡 How to Take b-nac 75mg injection

Strength: 75 mg/3 mL solution for injection

1This medicine is administered by a healthcare professional as a deep intramuscular injection.
2The injection is typically given into the gluteal muscle (buttock).
3The site should be rotated if multiple injections are given.
4Do not self-administer this medicine.
5After injection, remain under observation for a short period to monitor for any immediate reactions.

Dosage Information

Adult DosageThe usual adult dose is 75 mg (3 mL) administered by deep intramuscular injection into the gluteal region once daily. For severe pain, some clinicians may administer a second dose after 6 to 8 hours, but the total daily dose should not exceed 150 mg. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Treatment should be limited to the shortest duration necessary to control symptoms.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients are at increased risk of adverse effects, particularly gastrointestinal bleeding and renal impairment. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely.
Renal ImpairmentIn patients with mild to moderate renal impairment (eGFR 30-89 mL/min), no dose adjustment is typically necessary, but use with caution. In severe renal impairment (eGFR <30 mL/min), diclofenac is contraindicated. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with mild to moderate hepatic impairment, no dose adjustment is typically necessary, but use with caution. In severe hepatic impairment, diclofenac is contraindicated. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is 150 mg (two 75 mg injections).

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of b-nac 75mg injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold pack to the injection site if needed. It usually resolves within a day.
Nausea (Common (5-10%))
Take small sips of water and avoid heavy meals. If persistent, consult your doctor.
Headache (Common (5-10%))
Rest in a quiet, dark room. Consult your doctor if it persists or worsens.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel normal. Lie down if needed.
Drowsiness (Common (5-10%))
Avoid activities requiring alertness. It usually subsides as your body adjusts.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black, tarry stools, vomiting blood, or severe abdominal pain.
Myocardial infarction (Rare (<0.1%))
Call emergency services if you experience chest pain, shortness of breath, or pain radiating to the arm or jaw.
Stroke (Rare (<0.1%))
Seek immediate medical help if you have sudden weakness, confusion, trouble speaking, or vision changes.
Acute kidney injury (Rare (<0.1%))
Report decreased urine output, swelling in legs, or fatigue to your doctor immediately.
Hepatotoxicity (Rare (<0.1%))
Contact your doctor if you notice yellowing of skin or eyes, dark urine, or right upper abdominal pain.
Anaphylaxis (Very rare (<0.01%))
Call emergency services immediately if you experience swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Aseptic meningitis
Seek immediate medical attention if you develop severe headache, stiff neck, fever, or sensitivity to light.
Pancreatitis
Go to the emergency room if you have severe upper abdominal pain that radiates to your back, with nausea and vomiting.
Blood dyscrasias
Report unusual bruising, bleeding, fever, or sore throat to your doctor promptly.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Aspirin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
Cyclosporine Major
Lithium Major
ACE inhibitors Moderate
Diuretics Moderate
SSRIs Moderate

🚨 Major Interactions

  • Warfarin
  • Aspirin
  • Other NSAIDs
  • Corticosteroids
  • Methotrexate
  • Cyclosporine
  • Lithium
  • ACE inhibitors and ARBs
  • Diuretics
  • Selective serotonin reuptake inhibitors (SSRIs)

⚡ Moderate Interactions

  • Beta-blockers
  • Digoxin
  • Phenytoin
  • Rifampicin

🍷 Alcohol Interaction

Avoid alcohol while receiving this medicine. Alcohol can increase the risk of gastrointestinal bleeding, ulceration, and liver toxicity. It may also enhance the central nervous system effects such as dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to diclofenac or other NSAIDs","Active peptic ulcer disease or history of recurrent ulcers","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Cardiovascular risk: NSAIDs increase the risk of serious cardiovascular thrombotic events. Use the lowest effective dose for the shortest duration.","Gastrointestinal risk: NSAIDs increase the risk of GI bleeding, ulceration, and perforation. Use with caution in patients with a history of GI disease.","Renal risk: NSAIDs can cause renal impairment. Monitor renal function, especially in dehydrated patients or those with pre-existing renal disease.","Hepatic risk: Monitor liver function in patients on long-term therapy.","Hypersensitivity: Serious allergic reactions, including anaphylaxis, can occur. Discontinue immediately if suspected.","Skin reactions: Serious skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis have been reported.","Hematologic effects: Diclofenac inhibits platelet aggregation and may prolong bleeding time.","Use in elderly: Increased risk of adverse effects. Use with caution and monitor closely."]

🤱 Lactation Safety

Diclofenac is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but consult your doctor before use.

💊 Overdose Management

Overdose with diclofenac can cause nausea, vomiting, abdominal pain, gastrointestinal bleeding, lethargy, drowsiness, and in severe cases, acute renal failure and convulsions. Management includes supportive care, gastric lavage if within 1-2 hours of ingestion, activated charcoal, and monitoring of vital signs and renal function. There is no specific antidote. Hemodialysis is not effective in removing diclofenac.

⏰ Missed Dose

This medicine is typically administered by a healthcare professional in a clinical setting. If you miss a scheduled dose, contact your healthcare provider as soon as possible. Do not attempt to self-administer an extra dose.

Additional Safety Advice

General Safety

This medicine should only be administered by a qualified healthcare professional. Inform your doctor about all your medical conditions, especially if you have a history of stomach ulcers, heart disease, kidney or liver problems, or asthma. Do not use this medicine if you are allergic to diclofenac or other NSAIDs. Avoid alcohol while receiving this medicine as it can increase the risk of stomach bleeding. Do not drive or operate heavy machinery if you experience dizziness or drowsiness after the injection. Use the lowest effective dose for the shortest duration possible. Do not take other NSAIDs or blood thinners without consulting your doctor. Report any signs of bleeding, severe abdominal pain, chest pain, or difficulty breathing immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at increased risk of gastrointestinal bleeding, renal impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor renal and hepatic function closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. NSAIDs may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.

🏥 Post-Surgery Considerations

This medicine may be used for postoperative pain, but it is contraindicated in the setting of coronary artery bypass graft (CABG) surgery. Inform your surgeon and anesthesiologist about all medications you are taking.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may increase bleeding risk during dental procedures. Your dentist may recommend temporary discontinuation or additional precautions.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may increase pain or risk of injury while on this medicine. Gentle stretching and low-impact exercises may be beneficial, but consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is administered in a clinical setting, so you may need to arrange for transportation after receiving the injection.

🛑 When to Stop This Medicine

Stop this medicine and seek immediate medical attention if you experience signs of a serious allergic reaction, gastrointestinal bleeding, chest pain, or difficulty breathing. Do not stop prescribed therapy without consulting your doctor, as abrupt discontinuation may not be appropriate for your condition.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to increased risks of cardiovascular events, gastrointestinal bleeding, renal impairment, and hepatotoxicity. If long-term therapy is necessary, regular monitoring of renal and hepatic function, blood counts, and cardiovascular status is essential. The lowest effective dose should be used for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Acupuncture

May help with pain relief for some conditions.

Evidence: Moderate
Topical NSAIDs

Alternative for localized pain with fewer systemic side effects.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor about all medications you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. This medicine is for parenteral use and should be administered by a healthcare professional. Store it at room temperature, away from direct sunlight and moisture. If traveling by air, keep it in your carry-on luggage. Check customs regulations for carrying prescription medications in your destination country. It is advisable to carry a doctor&#039;s note explaining the medical need for this medicine.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old man with acute gout attack
Received this medicine injection for severe gout pain. Pain relief began within 30 minutes and lasted for about 6 hours. He was advised to avoid alcohol and follow up with his doctor for long-term management.
💡 Lesson: This medicine provides rapid relief for acute gout attacks, but lifestyle modifications and follow-up are essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts relieving pain within 10 to 30 minutes after intramuscular injection.

Q: How long does the effect last?

A: The analgesic effect usually lasts 4 to 6 hours, but this can vary.

Q: Can I take this medicine if I am pregnant?

A: This medicine is generally avoided during the third trimester. Consult your doctor for personalized advice.

Q: Can I take this medicine with other painkillers?

A: Do not take other NSAIDs concurrently. Consult your doctor before combining with any other pain medication.

Q: What should I avoid while taking this medicine?

A: Avoid alcohol, other NSAIDs, and activities requiring alertness if you experience dizziness or drowsiness.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for b-nac 75mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a steroid.
    Fact: This medicine is a nonsteroidal anti-inflammatory drug (NSAID), not a steroid.
  • Myth: This medicine can be self-administered at home.
    Fact: This medicine must be administered by a healthcare professional in a clinical setting.
  • Myth: This medicine is safe to use for long periods.
    Fact: This medicine is intended for short-term use only. Long-term use increases the risk of serious side effects.
  • Myth: This medicine can be taken with alcohol.
    Fact: Alcohol should be avoided as it increases the risk of gastrointestinal bleeding and liver toxicity.

🔄 Alternative Options

Generic Alternatives

  • Diclofenac sodium injection

Brand Alternatives

  • Voveran
  • Dynapar
  • Nac

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","class":"NSAID","route":"Intramuscular","onset":"10-30 minutes","duration":"4-6 hours"},{"medicine":"Ketorolac injection","class":"NSAID","route":"Intramuscular/Intravenous","onset":"10-30 minutes","duration":"4-6 hours"},{"medicine":"Paracetamol injection","class":"Analgesic","route":"Intravenous","onset":"5-10 minutes","duration":"4-6 hours"}]

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