aztric ct 25 tablet - Uses, Price, Side Effects & Substitutes
What is aztric ct 25 tablet used for?
Asar-CT 40/12.5 Tablet (Azilsartan medoxomil + Chlorthalidone) is used to treat CARDIAC. It contains Azilsartan medoxomil (40mg) + Chlorthalidone (25mg), which Azilsartan blocks AT1 receptor, reducing vasoconstriction and aldosterone secret. Always consult your doctor before use. Take as prescribed.
- Generic Name: Azilsartan medoxomil + Chlorthalidone
- Manufacturer: Intas Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ aztric ct 25 tablet Uses & Benefits
Hypertension (alone or in combination).
Off-label uses: Heart failure (limited data).
๐ Drug Information
| Generic Name(s) | Azilsartan medoxomil + Chlorthalidone |
| Brand Name | Asar-CT 40/12.5 Tablet |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Angiotensin II receptor blocker (ARB) + Thiazide-like diuretic |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Azilsartan blocks AT1 receptor, reducing vasoconstriction and aldosterone secretion; Chlorthalidone inhibits Na+/Cl- cotransporter in distal tubule, increasing diuresis.
Mechanism Steps
๐ก How to Take aztric ct 25 tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of aztric ct 25 tablet
โ Common Side Effects
- Dizziness
- Fatigue
- Diarrhea
- Hypokalemia
- Hyperuricemia
๐จ Serious Side Effects
- Angioedema
- Acute renal failure
- Hyperkalemia
- Hypotension
- Syncope
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Pancreatitis
- Stevens-Johnson syndrome
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Lithium | Major | Increased lithium toxicity risk |
| NSAIDs | Major | Reduced antihypertensive effect, increased renal impairment risk |
| ACE inhibitors | Major | Increased risk of hypotension, hyperkalemia, renal dysfunction |
| Aliskiren | Major | Increased risk of hypotension, hyperkalemia, renal dysfunction |
| Potassium-sparing diuretics | Major | Increased risk of hyperkalemia |
| Corticosteroids | Moderate | Reduced diuretic effect |
| Amphotericin B | Moderate | Increased risk of hypokalemia |
| Loop diuretics | Moderate | Additive diuretic effect, electrolyte imbalance |
| Dofetilide | Moderate | Increased risk of torsades de pointes due to hypokalemia |
| Antidiabetic agents | Minor | May alter blood glucose control |
| Alcohol | Minor | Additive hypotensive effect |
| Barbiturates | Minor | Additive hypotensive effect |
๐จ Major Interactions
- Lithium
- NSAIDs
- ACE inhibitors
- Aliskiren
- Potassium-sparing diuretics
โก Moderate Interactions
- Corticosteroids
- Amphotericin B
- Loop diuretics
- Dofetilide
โน๏ธ Minor Interactions
- Antidiabetic agents
- Alcohol
- Barbiturates
๐ฝ๏ธ Food Interactions
Avoid high-potassium foods; take with or without food.
๐ท Alcohol Interaction
May potentiate orthostatic hypotension.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Anuria, hypersensitivity to sulfonamides, severe renal impairment (CrCl <30 mL/min), pregnancy.
๐ Monitoring Parameters
Blood pressure, serum potassium, renal function, blood glucose, uric acid.
๐คฑ Lactation Safety
Not recommended; Chlorthalidone excreted in milk, Azilsartan unknown.
๐ Overdose Management
Symptomatic and supportive; monitor electrolytes, BP, renal function; consider gastric lavage.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose.