Aciloc Injection (Ranitidine 25mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, or throat, or difficulty breathing
- Severe dizziness, fainting, or a very slow heartbeat
- Confusion, hallucinations, or unusual behavior
- Unusual bruising or bleeding
- Severe abdominal pain or vomiting blood
- Yellowing of the skin or eyes
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is aztec 25mg injection used for?
This medicine is an injectable form of ranitidine, an H2 blocker that reduces stomach acid. It is given by a healthcare professional for conditions such as peptic ulcers, GERD, and Zollinger-Ellison syndrome when oral therapy is not possible. It works within 30 to 60 minutes and lasts about 8 to 12 hours. It must be dosed by a clinician, especially in kidney impairment.
- Generic Name: Ranitidine
- Manufacturer: Ind Swift Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 aztec 25mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा रैनिटिडीन का इंजेक्शन रूप है, जिसे पेट में एसिड बनने को कम करने के लिए दिया जाता है। इसका उपयोग पेट के अल्सर, गैस्ट्रिक अल्सर, एसिड रिफ्लक्स (जीईआरडी), और ज़ोलिंगर-एलिसन सिंड्रोम जैसी स्थितियों में किया जाता है, खासकर जब मरीज मुँह से दवा नहीं ले सकता या तुरंत एसिड कम करने की जरूरत होती है। यह दवा अस्पताल में डॉक्टर या नर्स द्वारा नस या मांसपेशी में इंजेक्शन के रूप में दी जाती है। यह 30 से 60 मिनट में काम करना शुरू कर देती है और लगभग 8 से 12 घंटे तक असर करती है। इसे अपने आप घर पर नहीं लगाना चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में सिरदर्द, चक्कर आना, कब्ज, जी मिचलाना, और इंजेक्शन लगाने की जगह पर दर्द या लालिमा शामिल हैं। कुछ मरीजों को नींद आना या थकान महसूस हो सकती है। गंभीर लेकिन दुर्लभ दुष्प्रभावों में धड़कन का धीमा होना, भ्रम, मतिभ्रम, और चेहरे, होंठ या गले में सूजन के साथ गंभीर एलर्जी प्रतिक्रिया शामिल हैं। अगर आपको सांस लेने में तकलीफ, बेहोशी, या असामान्य खून बहना दिखे तो तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा अस्पताल या क्लिनिक में ही दी जानी चाहिए। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो अपने डॉक्टर को बताएं। अपनी सभी दवाओं के बारे में डॉक्टर को जानकारी दें, खासकर वारफेरिन, फेनिटॉइन, थियोफिलिन, और कीटोकोनाज़ोल। किडनी की बीमारी में खुराक कम करनी पड़ सकती है, इसलिए किडनी की जांच जरूरी है। इस दवा को लेते समय शराब न पिएं। चक्कर या नींद आने तक गाड़ी न चलाएं। अपने आप खुराक बदलें या दवा बंद न करें।
💊 aztec 25mg injection Uses & Benefits
[{"condition":"Active duodenal ulcer","description":"This medicine reduces gastric acid secretion and helps heal duodenal ulcers in patients who cannot take oral therapy.","evidence":"Well-established"},{"condition":"Gastric ulcer","description":"It is used to decrease acid production and support healing of benign gastric ulcers when oral treatment is not feasible.","evidence":"Well-established"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"This medicine reduces acid reflux and relieves heartburn and esophageal irritation in hospitalized patients.","evidence":"Well-established"},{"condition":"Zollinger-Ellison syndrome","description":"It helps control excessive acid secretion in pathological hypersecretory conditions.","evidence":"Well-established"},{"condition":"Stress ulcer prophylaxis","description":"It is used in critically ill patients to prevent stress-related mucosal bleeding.","evidence":"Established"},{"condition":"Pre-anesthesia acid reduction","description":"It may be given before surgery to reduce stomach acid volume and acidity, lowering the risk of aspiration pneumonitis.","evidence":"Established"}]
Off-label uses: [{"condition":"Prevention of aspiration pneumonitis","description":"Sometimes used before emergency surgery to reduce gastric acid volume, though evidence is limited.","evidence":"Limited"},{"condition":"Non-ulcer dyspepsia","description":"Occasionally used for short-term relief of dyspepsia when oral therapy is not possible.","evidence":"Limited"}]
Primary treatment for: Peptic ulcer disease
Also treats: Gastroesophageal reflux disease, Zollinger-Ellison syndrome, Stress ulcer prophylaxis in critically ill patients
📋 Drug Information
| Generic Name(s) | Ranitidine |
| Brand Name | Aciloc 150 Tablet |
| Manufacturer | Ind Swift Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | H2 Receptor Blocker |
| Route of Administration | Parenteral (intravenous or intramuscular injection). This medicine is not for oral use in this form |
| Storage | Store this medicine at room temperature between 15°C and 30°C (59°F to 86°F). Protect it from light and moisture. Do not freeze. Keep it in its original carton or container until it is time to use it. Once prepared for intravenous infusion, use it within the time recommended by the manufacturer or hospital pharmacy. |
| Shelf Life | The shelf life is typically 24 to 36 months from the date of manufacture, depending on the manufacturer and packaging. Always check the expiry date on the label before use. Do not use the medicine if the solution is discolored or contains particles. |
| WHO Guideline | Not established from the available information for this specific injectable product. Ranitidine has been widely used for acid-related disorders, but current guidelines often favor proton pump inhibitors for many indications. Follow your local hospital protocol and your doctor's advice. |
| ICMR Guideline | Not established from the available information for this specific injectable product. Follow the prescribing advice of your treating clinician and local institutional guidelines. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by competitively blocking histamine at the H2 receptors located on the basolateral membrane of gastric parietal cells. This blockade reduces intracellular cyclic AMP levels, which in turn decreases the activity of the proton pump and lowers both basal and stimulated gastric acid secretion. It also reduces pepsin output and gastric volume. Because it acts on H2 receptors rather than the proton pump itself, it is less potent than proton pump inhibitors but works quickly when given intravenously.
Mechanism Steps
💡 How to Take aztec 25mg injection
Strength: This medicine is supplied as a 25 mg strength in an injectable form. It is intended for parenteral use only.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, age, weight, kidney and liver function, and other medicines. For active ulcers or reflux, a common adult intravenous dose is 50 mg every 6 to 8 hours, but the exact dose and frequency will be decided by your doctor. For Zollinger-Ellison syndrome, higher doses may be needed. In kidney impairment, the dose is usually reduced to 50 mg every 12 to 24 hours or as directed. The injection should be given slowly over at least 2 minutes. Do not self-administer this medicine. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific injectable product. Consult a pediatrician or specialist for dosing in children. |
| Elderly Dosage | Elderly patients are more sensitive to the central nervous system effects of this medicine, such as confusion and drowsiness. The dose may need to be reduced, especially if kidney function is reduced. Kidney function should be checked before and during treatment. The clinician will decide the appropriate dose based on the patient's condition and kidney function. |
| Renal Impairment | In patients with kidney impairment, the dose of this medicine must be reduced. For moderate kidney impairment, a common adjustment is 50 mg every 12 hours. For severe kidney impairment, 50 mg every 24 hours may be used. The exact dose must be determined by a qualified clinician based on the measured kidney function. Monitoring of kidney function is recommended during treatment. |
| Hepatic Impairment | In patients with liver impairment, this medicine is usually used with caution. Dose reduction may be needed because the medicine is partly metabolized by the liver. The clinician will decide the appropriate dose based on liver function tests and the patient's overall condition. |
| Maximum Daily Dose | The maximum daily dose of this medicine must be determined by a qualified clinician. For most adult indications, the total daily dose usually does not exceed 200 mg to 300 mg per day, but higher doses may be used in Zollinger-Ellison syndrome under specialist supervision. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of aztec 25mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Phenytoin | Major | |
| Theophylline | Major | |
| Procainamide | Major | |
| Ketoconazole | Moderate | |
| Itraconazole | Moderate | |
| Atazanavir | Moderate | |
| Delavirdine | Moderate | |
| Antacids | Minor | |
| Metoclopramide | Minor |
🚨 Major Interactions
- Warfarin
- Phenytoin
- Theophylline
- Procainamide
⚡ Moderate Interactions
- Ketoconazole
- Itraconazole
- Atazanavir
- Delavirdine
🍷 Alcohol Interaction
Alcohol should be avoided while receiving this medicine. Alcohol increases gastric acid secretion and can worsen ulcers or reflux. It can also add to dizziness and drowsiness caused by this medicine. If you drink alcohol regularly, tell your doctor so they can advise you appropriately.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to ranitidine or other H2-receptor antagonists","Use in children under 1 month of age unless specifically directed by a specialist","Severe kidney impairment without appropriate dose adjustment","Porphyria, because this medicine may trigger attacks"]
⚠️ Warnings & Precautions
["This medicine must be given by a healthcare professional only.","The intravenous dose should be given slowly over at least 2 minutes to avoid low blood pressure and slow heart rate.","Dose reduction is needed in patients with kidney impairment.","Elderly patients are more likely to develop confusion or delirium.","This medicine may mask the symptoms of stomach cancer, so a doctor should evaluate persistent symptoms.","Avoid alcohol while receiving this medicine.","Do not drive or operate machinery until you know how this medicine affects you.","Tell your doctor about all other medicines you take, especially warfarin, phenytoin, and theophylline.","Use with caution in patients with liver disease.","Use with caution in patients with heart rhythm problems."]
🤱 Lactation Safety
This medicine passes into breast milk. It is generally considered compatible with breastfeeding, but the amount that reaches the infant is small. Because it can reduce stomach acid in the infant, monitor for feeding problems or unusual sleepiness. Consult your doctor before breastfeeding while receiving this medicine.
💊 Overdose Management
Overdose with this medicine is uncommon because it is given by healthcare professionals. Symptoms of overdose may include severe dizziness, slow heartbeat, low blood pressure, confusion, and difficulty breathing. Treatment is supportive and includes monitoring of vital signs, heart rhythm, and kidney function. There is no specific antidote. If an overdose is suspected, seek emergency medical care immediately. Hemodialysis may remove some of the medicine from the blood in severe cases.
⏰ Missed Dose
Because this medicine is given by a healthcare professional in a hospital or clinic, missed doses are managed by the medical team. If you miss a scheduled dose at home, contact your doctor or nurse for instructions. Do not try to give yourself an extra dose to catch up. If you are receiving this medicine at a clinic, the staff will adjust the schedule as needed.
Additional Safety Advice
This medicine must only be given by a healthcare professional in a setting where emergency equipment is available. Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. Inform your doctor about all other medicines you take, especially warfarin, phenytoin, theophylline, ketoconazole, and any medicine for heart rhythm. Your kidney function may need to be checked before and during treatment because the dose often needs adjustment in kidney disease. Do not drive or operate heavy machinery until you know how this medicine affects you, as it can cause dizziness or drowsiness. Avoid alcohol while receiving this medicine because it can worsen stomach irritation and increase drowsiness. Do not stop or change the dose on your own; the treating clinician will decide when to switch to oral therapy or stop treatment.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to experience confusion, delirium, and drowsiness with this medicine. Kidney function often declines with age, so the dose may need to be reduced. Monitor elderly patients closely for changes in mental status and adjust the dose as needed.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss this medicine with your doctor before conception. This medicine crosses the placenta, and while human data have not shown a clear increase in birth defects, the data are limited. Your doctor may consider alternative treatments if appropriate.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to reduce the risk of stress ulcers or aspiration. It is given by injection while the patient is recovering. The dose and duration will be decided by the surgical team based on the patient's condition and kidney function.
🦷 Dental Procedures
Inform your dentist if you are receiving this medicine. It does not usually interfere with dental procedures, but your dentist should know about all medicines you are taking. If you need sedation or anesthesia, tell the dentist and anesthesiologist about this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause dizziness or drowsiness. Avoid strenuous exercise or activities that require balance until you know how the medicine affects you. If you feel dizzy or weak, sit down and rest. Ask your doctor when it is safe to resume your normal exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is usually given in a hospital or clinic, so it may affect your work schedule during treatment. It can cause dizziness or drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. Ask your doctor when you can return to work and whether any work restrictions are needed.
🛑 When to Stop This Medicine
This medicine is stopped by your doctor when your condition improves or when you can take oral medicines. Do not stop it on your own. If you experience serious side effects such as severe allergic reaction, slow heartbeat, or confusion, the doctor will stop the medicine immediately. Always consult your doctor before stopping any medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is uncommon because it is usually given for short periods in a hospital. If used for a long time, it may lead to vitamin B12 deficiency, increased risk of certain infections, and rarely, breast symptoms in men. Long-term use should be reviewed regularly by a doctor, and the need for continued treatment should be reassessed. Kidney and liver function should be monitored during prolonged therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Medicines such as pantoprazole or omeprazole may be used instead, depending on the condition.
Evidence: Well-establishedOral ranitidine or famotidine may be used once the patient can take medicines by mouth.
Evidence: Well-establishedAvoiding trigger foods, reducing alcohol, and quitting smoking can help manage acid-related symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known vaccine interactions with this medicine. However, if you are due for any vaccine, inform your doctor that you are receiving this medicine. Live vaccines should generally be avoided in patients who are critically ill or immunocompromised, but this is not directly related to this medicine.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not freeze the injection.
✅ DO
Keep in the original carton or container.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Protect from light and moisture.
❌ DON'T
Do not store in the bathroom.
✅ DO
Check the expiry date before use.
❌ DON'T
Do not use if the solution is discolored or contains particles.
✈️ Traveling with This Medicine
This medicine is given by a healthcare professional, so travel advice mainly applies if you are being discharged with a prescription for a similar oral medicine. If you must travel with this injectable, carry it in its original packaging with the prescription copy. Keep it at room temperature and protect it from light and moisture. If you are crossing time zones, ask your doctor how to adjust the dosing schedule. Check customs rules for carrying injectable medicines before you travel. Always carry a letter from your doctor explaining why you need this medicine.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts reducing stomach acid within 30 to 60 minutes after injection. The effect lasts about 8 to 12 hours.
A: It is given by a healthcare professional as an injection into a vein or muscle. It is not for home use.
A: Common side effects include headache, dizziness, constipation, nausea, and pain at the injection site.
A: This medicine crosses the placenta. Use it only if your doctor decides the benefit outweighs the risk.
A: The dose needs to be reduced in kidney impairment. Your doctor will check your kidney function and adjust the dose.
A: It is best to avoid alcohol because it can worsen stomach irritation and increase drowsiness.
🤔 Common Patient Concerns
🔄 Substitutes for aztec 25mg injection
View AllAlternative brands with exact same active ingredient:
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ozotac 25mg injectionOzone Pharmaceuticals Ltd ₹1.92 17.9% CHEAPER
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acigo 25mg injectionAncalima Lifesciences Ltd ₹2.19 6.4% CHEAPER
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nicotac 25mg injectionAbbott ₹2.23 4.7% CHEAPER
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lantac 25mg injectionLaborate Pharmaceuticals India Ltd ₹2.34 SAME PRICE
-
afdiloc injectionAnglo-French Drugs & Industries Ltd ₹2.36 0.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken at home by yourself.
Fact: This medicine is an injectable and must only be given by a trained healthcare professional. - Myth: This medicine is the same as an antacid.
Fact: This medicine reduces acid production at the source, while antacids only neutralize acid already in the stomach. - Myth: This medicine works instantly.
Fact: It starts working within 30 to 60 minutes, not instantly. - Myth: This medicine is safe for everyone with stomach pain.
Fact: It is not for everyone. People with porphyria or severe kidney problems may need to avoid it or take a lower dose.
🔄 Alternative Options
Generic Alternatives
- Ranitidine injection
Brand Alternatives
- Aciloc injection