azrol 25mcg inhaler - Salmeterol (25mcg) medicine

azrol 25mcg inhaler - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Sun Pharmaceutical Industries Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is azrol 25mcg inhaler used for?

Azrol 25mcg Inhaler (Salmeterol) is used to treat RESPIRATORY. It contains Salmeterol (25mcg), which Selective long-acting beta2-adrenoceptor agonist that relaxes bronchial smooth m. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Salmeterol
  • Manufacturer: Sun Pharmaceutical Industries Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š azrol 25mcg inhaler Uses & Benefits

Maintenance treatment of asthma and COPD; prevention of exercise-induced bronchospasm.

Off-label uses: Prevention of bronchospasm in chronic bronchitis; off-label use in some cases of bronchiectasis.

๐Ÿ“‹ Drug Information

Generic Name(s)Salmeterol
Brand NameAzrol 25mcg Inhaler
ManufacturerSun Pharmaceutical Industries Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassLong acting ฮฒ2-agonists
Route of AdministrationInhalation
StorageStore at 20-25ยฐC (68-77ยฐF); protect from heat and direct sunlight; keep canister away from open flame.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionInhaled salmeterol acts locally in the lungs; systemic absorption occurs via the lungs and gastrointestinal tract.
DistributionDistributes extensively into tissues, with highest concentrations in lungs and gastrointestinal tract.
Protein Binding94-98%
MetabolismExtensively metabolized in the liver by CYP3A4 to alpha-hydroxysalmeterol.
Half-Life5.5 hours
ExcretionPrimarily in feces (60%) and urine (25%) as metabolites.
BioavailabilityLow systemic bioavailability due to extensive first-pass metabolism; inhaled dose primarily acts loc
Onset of Action30-60 minutes
Peak Plasma TimeNot clinically relevant; local effect peaks within 1-2 hours.
Duration of Action12 hours

How It Works

Selective long-acting beta2-adrenoceptor agonist that relaxes bronchial smooth muscle.

Mechanism Steps

1Binds to beta2-adrenergic receptors on bronchial smooth muscle
2Activates Gs protein, increasing adenylate cyclase activity
3Raises intracellular cAMP levels

๐Ÿ’ก How to Take azrol 25mcg inhaler

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of azrol 25mcg inhaler

โœ… Common Side Effects

  • Headache
  • Tremor
  • Palpitations
  • Cough
  • Throat irritation

๐Ÿšจ Serious Side Effects

  • Paradoxical bronchospasm
  • Hypokalemia
  • Cardiac arrhythmias
  • Hypertension

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • QT prolongation
  • Torsades de pointes

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Propranolol Major Antagonism of bronchodilator effect
Phenelzine Major Increased risk of hypertensive crisis
Amitriptyline Major Enhanced cardiovascular effects
Furosemide Moderate Hypokalemia risk
Prednisone Moderate Increased hypokalemia risk
Theophylline Moderate Increased cardiovascular effects
Albuterol Minor Additive bronchodilation
Ipratropium Minor Additive bronchodilation

๐Ÿšจ Major Interactions

  • Non-selective beta-blockers
  • MAOIs
  • Tricyclic antidepressants

โšก Moderate Interactions

  • Diuretics
  • Corticosteroids
  • Xanthine derivatives

โ„น๏ธ Minor Interactions

  • Other beta-agonists
  • Anticholinergics

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to salmeterol or any excipient; status asthmaticus; concurrent use of non-selective beta-blockers.

๐Ÿ“Š Monitoring Parameters

Peak flow, FEV1, symptom control, heart rate, blood pressure, serum potassium.

๐Ÿคฑ Lactation Safety

Caution; excreted in breast milk in small amounts.

๐Ÿ’Š Overdose Management

Supportive care; monitor cardiac function; consider cardioselective beta-blocker with caution.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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