Dynaglipt-M Tablet SR: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Rapid breathing or difficulty breathing
- Severe abdominal pain that may radiate to the back
- Muscle pain with extreme tiredness
- Yellowing of skin or eyes (jaundice)
- Decreased urine output or swelling in legs
- Severe hypoglycemia symptoms (confusion, shakiness, sweating)
- Signs of allergic reaction (rash, swelling of face/lips/throat)
If experiencing severe symptoms, call emergency services immediately.
What is azneten m tablet er used for?
This medicine is a combination of Metformin and Teneligliptin used to treat type 2 diabetes. It helps control blood sugar by improving insulin sensitivity and increasing insulin release when needed. It is taken orally once daily with a meal.
- Generic Name: Metformin + Teneligliptin
- Manufacturer: Daylon Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 azneten m tablet er के बारे में (Hindi Summary)
उपयोग: यह दवा टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए इस्तेमाल की जाती है। इसमें मेटफॉर्मिन और टेनेलिग्लिप्टिन दो सक्रिय तत्व होते हैं जो मिलकर ब्लड शुगर को कंट्रोल करने में मदद करते हैं। मेटफॉर्मिन लिवर में शुगर बनना कम करता है और शरीर की इंसुलिन के प्रति संवेदनशीलता बढ़ाता है, जबकि टेनेलिग्लिप्टिन पैंक्रियाज से इंसुलिन रिलीज को बढ़ाता है। यह दवा उन वयस्कों के लिए है जिनका डायबिटीज डाइट और एक्सरसाइज से कंट्रोल नहीं हो पाता। इसे खाने के साथ रोज एक बार लेना चाहिए। इसका सेवन डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के आम साइड इफेक्ट्स में जी मिचलाना, दस्त, पेट में असहजता, सिरदर्द और मुंह में धातु जैसा स्वाद शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर साइड इफेक्ट्स दुर्लभ हैं लेकिन लैक्टिक एसिडोसिस (खून में लैक्टिक एसिड का बढ़ना) हो सकता है, जिसमें मांसपेशियों में दर्द, सांस लेने में तकलीफ, पेट दर्द और अत्यधिक थकान हो सकती है। पैंक्रियाटाइटिस (अग्नाशय की सूजन) भी हो सकती है। अगर आपको कोई भी गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को कम या ज्यादा न करें और बिना सलाह के बंद न करें। इसे खाने के साथ लें ताकि पेट की तकलीफ कम हो। दिनभर पर्याप्त पानी पिएं। शराब का सेवन न करें क्योंकि इससे लैक्टिक एसिडोसिस का खतरा बढ़ सकता है। अपने ब्लड शुगर की नियमित जांच करें। अगर आपको किडनी या लिवर की समस्या है तो डॉक्टर को बताएं। सर्जरी या कंट्रास्ट टेस्ट से पहले डॉक्टर को इस दवा के बारे में जरूर बताएं।
💊 azneten m tablet er Uses & Benefits
[{"condition":"Type 2 Diabetes Mellitus","description":"Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who are not adequately controlled on Metformin alone or who require combination therapy.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prediabetes","description":"Sometimes prescribed off-label to delay progression to diabetes in high-risk individuals, but this is not an approved indication.","evidence":"Limited"},{"condition":"Polycystic Ovary Syndrome (PCOS)","description":"Metformin component may be used off-label for insulin resistance in PCOS, but the combination with Teneligliptin is not established for this use.","evidence":"Limited"}]
Primary treatment for: Type 2 Diabetes Mellitus
Also treats: Obesity, Metabolic Syndrome, Polycystic Ovary Syndrome (off-label for Metformin component)
📋 Drug Information
| Generic Name(s) | Metformin + Teneligliptin |
| Brand Name | Afoglip M 500 Tablet ER |
| Manufacturer | Daylon Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Antidiabetic (Biguanide + DPP-4 inhibitor) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antidiabetic agents with complementary mechanisms. Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that prolongs the activity of incretin hormones (GLP-1 and GIP), which stimulate insulin release from pancreatic beta cells and reduce glucagon secretion from alpha cells, leading to better blood sugar control.
Mechanism Steps
💡 How to Take azneten m tablet er
Strength: Tablet containing Metformin 500 mg and Teneligliptin 20 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once daily with a meal, preferably in the morning. The dose may be adjusted by your doctor based on your blood sugar levels, kidney function, and other medications. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially regarding renal function. Dose should be adjusted based on renal function. Regular monitoring of kidney function is recommended. |
| Renal Impairment | Metformin dose should be adjusted in renal impairment. In patients with eGFR 30-45 mL/min/1.73 m², Metformin should be used with caution and at reduced doses. Metformin is contraindicated if eGFR <30 mL/min/1.73 m². Teneligliptin dose may need adjustment in moderate to severe renal impairment. Consult your doctor for personalized dosing. |
| Hepatic Impairment | Metformin should be avoided in severe hepatic impairment due to increased risk of lactic acidosis. Teneligliptin has not been studied in severe hepatic impairment. Consult your doctor for dose adjustment. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet containing Metformin 500 mg and Teneligliptin 20 mg. Do not exceed this dose unless directed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of azneten m tablet er
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Contrast media | Major | |
| Alcohol | Major | |
| Diuretics | Major | |
| Sulfonylureas | Moderate | |
| Insulin | Moderate | |
| CYP3A4 inhibitors | Moderate | |
| CYP3A4 inducers | Moderate | |
| NSAIDs | Minor | |
| ACE inhibitors | Minor | |
| Cationic drugs | Major |
🚨 Major Interactions
- Contrast media (iodinated)
- Alcohol
- Diuretics (e.g., furosemide)
- Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, vancomycin)
⚡ Moderate Interactions
- Sulfonylureas (e.g., glimepiride, glipizide)
- Insulin
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. It increases the risk of lactic acidosis, a rare but serious complication of Metformin, and can also cause hypoglycemia. If you drink alcohol, discuss safe limits with your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Lactic acidosis: Rare but serious. Risk increases with renal impairment, liver disease, alcohol use, and conditions causing tissue hypoxia.","Pancreatitis: Has been reported with DPP-4 inhibitors. Monitor for signs.","Hypoglycemia: Risk increases when used with insulin or sulfonylureas.","Renal function: Monitor regularly; dose adjustment may be needed.","Vitamin B12 deficiency: Long-term Metformin use may cause deficiency. Monitor levels.","Surgery: Discontinue temporarily before surgery and restart after renal function is confirmed normal.","Alcohol: Avoid excessive consumption.","Pregnancy and lactation: Consult doctor before use."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause hypoglycemia, lactic acidosis, or pancreatitis. Seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered for Metformin overdose if lactic acidosis is present. There is no specific antidote for Teneligliptin.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor. Take it with a meal to reduce stomach upset. Drink plenty of water throughout the day. Avoid excessive alcohol consumption while taking this medicine, as it increases the risk of lactic acidosis. Monitor your blood sugar levels regularly as advised. Inform your doctor if you have kidney or liver problems, or if you are scheduled for surgery or imaging tests using contrast dyes. Tell your doctor about all other medicines you are taking, including over-the-counter products. If you experience symptoms like rapid breathing, muscle pain, or extreme fatigue, seek medical help immediately. Do not use this medicine if you are pregnant or planning pregnancy without consulting your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can increase the risk of Metformin accumulation and lactic acidosis. Regular monitoring of renal function is essential. Dose adjustments may be needed. Elderly patients may also be more sensitive to the blood sugar-lowering effects, increasing the risk of hypoglycemia.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Diabetes should be well-controlled before conception to reduce the risk of complications. Your doctor may switch you to insulin or another medicine that is safer during pregnancy. Do not stop or change your medicine without medical advice.
🏥 Post-Surgery Considerations
This medicine should be temporarily discontinued before surgery and restarted only after your doctor confirms that your kidney function is normal. This is to prevent lactic acidosis. Inform your surgeon and anesthesiologist about all medicines you are taking.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. Dental procedures may cause stress and affect blood sugar levels. Monitor your blood sugar before and after the procedure. If you are unable to eat normally after dental work, consult your doctor about adjusting your diabetes medicines.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is encouraged as part of diabetes management, but monitor your blood sugar before and after exercise. If you take other diabetes medicines that can cause hypoglycemia, carry fast-acting sugar with you. Stay hydrated during exercise. Consult your doctor before starting a new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or low blood sugar in some people, which can affect your ability to drive or operate machinery. Avoid driving if you feel dizzy or shaky. Take regular breaks if your job involves prolonged standing or physical activity. Inform your employer about your condition and keep a source of fast-acting sugar at your workplace.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects like lactic acidosis, pancreatitis, or severe allergic reactions, stop the medicine and seek immediate medical attention. Your doctor may adjust or discontinue the medicine based on your condition and test results.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to vitamin B12 deficiency due to Metformin. Regular monitoring of vitamin B12 levels is advised. Kidney function should be checked at least annually. The combination has been shown to be safe and effective for long-term management of type 2 diabetes when used as prescribed. Do not stop the medicine without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise are the cornerstone of diabetes management and can complement medicine.
Evidence: Well-establishedSulfonylureas, SGLT2 inhibitors, or GLP-1 receptor agonists may be considered based on individual needs.
Evidence: Well-establishedMay be required if oral agents fail to control blood sugar.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, people with diabetes are at higher risk of complications from infections like influenza and pneumonia. Ensure you are up to date with recommended vaccinations, including annual flu shots and pneumococcal vaccine, as advised by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry your medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the timing of your dose. Carry enough supply for the entire trip plus extra in case of delays. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within a few days, but the full effect on HbA1c may take 2-3 months. Regular monitoring is important.
A: It is best taken with food to reduce stomach upset. Taking it without food may increase the risk of nausea and diarrhea.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Do not stop taking this medicine without consulting your doctor. Blood sugar may rise again if you stop suddenly.
A: Metformin can affect kidney function in some people. Your doctor will monitor your kidney function regularly and adjust the dose if needed.
🤔 Common Patient Concerns
🔄 Substitutes for azneten m tablet er
View AllAlternative brands with exact same active ingredient:
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tenlizem-m500 sr tabletZeelab Pharmacy Pvt Ltd ₹25.00 77.2% CHEAPER
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kriptan m 500mg/20mg tablet srZylig Lifesciences ₹35.63 67.5% CHEAPER
-
davaindia metformin+teneligliptin 500mg/20mg tablet srDavaindia Generic Pharmacy ₹46.00 58.1% CHEAPER
-
ecoglip-tm tablet srOzone Pharmaceuticals Ltd ₹50.00 54.4% CHEAPER
-
gudglip m 500mg/20mg tabletCurewin Hylico Pharma Pvt Ltd ₹51.56 53% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps manage blood sugar levels but does not cure diabetes. Lifestyle changes and ongoing treatment are essential. - Myth: It can be taken without food.
Fact: It should be taken with food to reduce stomach upset and improve tolerability. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol increases the risk of lactic acidosis and hypoglycemia. It should be avoided. - Myth: This medicine causes weight gain.
Fact: Metformin is weight-neutral or may cause slight weight loss. Teneligliptin is weight-neutral.
🔄 Alternative Options
Generic Alternatives
- Metformin 500 mg + Teneligliptin 20 mg tablet (generic)
Brand Alternatives
- Dynaglipt-M Tablet SR