Azined SF Kit - Uses, Price, Side Effects, Dosage
💊 What is azined sf kit used for?
Fluconazole + Azithromycin
Accord Pharmaceuticals
Allopathy
Category A
🇮🇳 azined sf kit के बारे में संक्षिप्त जानकारी
azined sf kit का उपयोग मुख्य रूप से gynaecological और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Fluconazole (150mg) + Azithromycin (1gm) मौजूद है।
📋 Complete Drug Information
| Generic Name(s) | Fluconazole + Azithromycin |
|---|---|
| Brand Name | Azithral XP 150mg/1000mg/1000mg Tablet |
| Manufacturer | Accord Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Antifungal + Antibiotic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from light and moisture. |
🔬 Pharmacology
Pharmacokinetics
Mechanism of Action
Fluconazole inhibits fungal cytochrome P450 14α-demethylase, preventing ergosterol synthesis; Azithromycin binds to 50S ribosomal subunit, inhibiting bacterial protein synthesis.
Step-by-Step Mechanism
💡 How to take azined sf kit
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose.
- ✅ Complete the full course of medication.
- ✅ Store at room temperature (20-25°C), protect from light and moisture.
⚠️ Side Effects of azined sf kit
✅ Common Side Effects
- Nausea
- Diarrhea
- Abdominal pain
- Headache
- Vaginal discharge
🚨 Serious Side Effects
- QT prolongation
- Torsades de pointes
- Hepatotoxicity
- Stevens-Johnson syndrome
- Anaphylaxis
⚠️ Rare Side Effects
- Agranulocytosis
- Thrombocytopenia
- Pancreatitis
- Hearing loss
- Tinnitus
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Cisapride | Major | Risk of cardiac arrhythmias |
| Ergotamine | Major | Ergotism risk |
| Digoxin | Moderate | Increased digoxin levels |
| Oral Contraceptives | Moderate | Reduced contraceptive efficacy |
🚨 Major Interactions
- Warfarin
- Cisapride
- Terfenadine
- Astemizole
- Pimozide
- Quinidine
- Ergotamine
⚡ Moderate Interactions
- Oral hypoglycemics
- Phenytoin
- Rifampin
- Cyclosporine
- Theophylline
- Digoxin
🍽️ Food Interactions
Azithromycin absorption may be reduced with food; fluconazole unaffected.
🍷 Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to azithromycin, fluconazole, or other azoles; concurrent use with cisapride, terfenadine, astemizole, pimozide, quinidine, ergotamine.
📊 Monitoring Parameters
Liver function tests, renal function, ECG (if risk factors), signs of superinfection.
🤱 Lactation Safety
Fluconazole and azithromycin are excreted in breast milk; use with caution.
💊 Overdose
Supportive care; gastric lavage if recent; monitor ECG for QT prolongation; hemodialysis may remove fluconazole.
⏰ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose.