azeemal 15mg injection - Arteether (15mg) medicine

Azeemal 15mg Injection (arteether): Complete Medicine Guide

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🏭 Euporie Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 29, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not classified by old letter categories. This medicine is not recommended during the first trimester of pregnancy unless the doctor decides it is absolutely necessary because of severe malaria. In later pregnancy, it may be used if needed. Always consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for severe malaria, but not first-line in all guidelines.
Reviewed by
SaathiMed Expert Panel | Oct 29, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe rash or itching
  • Very slow or irregular heartbeat
  • Fainting or severe dizziness
  • Yellowing of skin or eyes
  • Decreased urine output
  • Severe abdominal pain
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is azeemal 15mg injection used for?

This medicine is an intramuscular injection containing Arteether 15mg, used to treat severe malaria. It is given by a healthcare professional, usually once daily for 3 days, followed by oral antimalarial tablets. It works by killing the malaria parasite in the blood.

  • Generic Name: Arteether
  • Manufacturer: Euporie Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 azeemal 15mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा आर्टीथर 15mg इंजेक्शन के रूप में उपलब्ध है और गंभीर मलेरिया के इलाज के लिए दी जाती है। यह मलेरिया परजीवी को मारती है और बुखार, ठंड लगना, सिरदर्द और मांसपेशियों के दर्द जैसे लक्षणों को कम करती है। यह इंजेक्शन डॉक्टर या नर्स द्वारा मांसपेशी में लगाया जाता है, आमतौर पर रोज एक बार तीन दिन तक। इसके बाद मलेरिया की गोलियां पूरी करनी चाहिए ताकि बीमारी दोबारा न हो। यह दवा घर पर खुद से नहीं लगानी चाहिए।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में इंजेक्शन वाली जगह पर दर्द, हल्का बुखार, सिरदर्द, चक्कर आना, जी मिचलाना और उल्टी शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर सांस लेने में तकलीफ, चेहरे या गले में सूजन, त्वचा पर चकत्ते, धड़कन धीमी होना, पेशाब कम आना, या आंखों-त्वचा का पीला पड़ना हो, तो तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा सिर्फ डॉक्टर या प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही लगाई जानी चाहिए। खुद से इंजेक्शन न लगाएं। अगर आपको किसी दवा से एलर्जी है, तो डॉक्टर को बताएं। गर्भवती महिलाओं को पहले तीन महीनों में यह दवा नहीं दी जाती, जब तक डॉक्टर जरूरी न समझें। स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। इंजेक्शन के बाद चक्कर आ सकते हैं, इसलिए आराम करें और गाड़ी न चलाएं। डॉक्टर द्वारा बताई गई मलेरिया की गोलियां पूरी करें। शराब न पिएं।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 azeemal 15mg injection Uses & Benefits

[{"condition":"Severe and complicated malaria","description":"This medicine is used to treat severe malaria caused by Plasmodium falciparum, especially when oral treatment is not possible.","evidence":"Well-established"},{"condition":"Cerebral malaria","description":"It is used in patients with cerebral malaria, a serious form of malaria affecting the brain.","evidence":"Well-established"},{"condition":"Malaria in patients who cannot take oral medicines","description":"It is given when patients are vomiting, unconscious, or unable to swallow tablets.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Severe malaria

Also treats: Cerebral malaria, Complicated malaria

📋 Drug Information

Generic Name(s)Arteether
Brand NameArtisun 150mg Injection
ManufacturerEuporie Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI MALARIALS
Action ClassAntimalarial- Artemisinin and derivatives
Route of AdministrationIntramuscular (into the muscle, usually the buttock)
StorageStore in a cool, dry place away from direct sunlight. Do not freeze. Keep out of reach of children. Follow the storage instructions on the pack.
Shelf LifeNot established from the available information. Check the expiry date on the pack.
WHO GuidelineThe World Health Organization recommends artemisinin-based combination therapies for the treatment of uncomplicated malaria and intravenous or intramuscular artesunate for severe malaria. Arteether is an artemisinin derivative that may be used for severe malaria where artesunate is not available, but it is not the first-line choice in WHO guidelines. Always follow national malaria treatment guidelines.
ICMR GuidelineThe Indian Council of Medical Research (ICMR) guidelines for malaria treatment in India recommend artesunate as the first-line treatment for severe malaria. Arteether may be used as an alternative in some settings. Please consult the latest ICMR guidelines for specific recommendations.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always confirm the diagnosis of severe malaria with a blood test before giving this injection.
2
Give the injection deep intramuscularly in the buttock, rotating sites to reduce pain.
3
Monitor the patient's heart rate and blood pressure during and after the injection.
4
Follow the injection course with a full course of oral artemisinin-based combination therapy to prevent recurrence.
5
Check for allergies to artemisinin drugs before administering.
6
In pregnant women, use only if the benefit outweighs the risk, especially in the first trimester.
7
Advise the patient to avoid alcohol during treatment.
8
Educate the patient about the importance of completing the full treatment course.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High fever with chills
This medicine is used for severe malaria which causes these symptoms.
Likely Use
✅
Severe headache
May be a symptom of severe malaria.
Likely Use
✅
Vomiting
This medicine is used when oral medicines cannot be taken due to vomiting.
Likely Use
❌
Common cold
This medicine is not for viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAfter intramuscular injection, Arteether is absorbed from the muscle into the bloodstream. The absorption may be slow and variable depending on the injection site and blood flow. Not established from the available information for exact absorption rate.
DistributionAfter absorption, Arteether is distributed to various tissues in the body. It is believed to cross the blood-brain barrier, which is important for treating cerebral malaria. Not established from the available information for exact distribution volume.
Protein BindingNot established from the available information.
MetabolismArteether is metabolized in the liver into its active metabolite, dihydroartemisinin. This metabolite also has antimalarial activity. The metabolism involves certain liver enzymes, but the exact pathways are not fully established from the available information.
Half-LifeNot established from the available information.
ExcretionArteether and its metabolites are mainly excreted in the urine and bile. Not established from the available information for exact excretion proportions.
BioavailabilityNot established from the available information.
Onset of ActionThe antimalarial effect starts within a few hours after injection. Fever and other symptoms may begin to improve within 24 to 48 hours.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effect lasts for about 24 hours, which is why the injection is usually given once daily. However, a full course of treatment is needed to cure the infection.

How It Works

Arteether is a derivative of artemisinin. It works by entering the malaria parasite and reacting with iron-containing compounds inside the parasite. This reaction produces harmful substances called free radicals that damage the parasite's proteins and membranes. The parasite is killed quickly, especially in the early stages of its life cycle. This helps to reduce the number of parasites in the blood rapidly and prevents the infection from becoming more severe.

Mechanism Steps

1
Entry into parasite: Arteether enters the malaria parasite after being injected into the muscle and reaching the bloodstream.
2
Activation by iron: Inside the parasite, Arteether reacts with iron-containing molecules, especially heme, which is released when the parasite digests hemoglobin.
3
Free radical formation: This reaction produces free radicals that are highly reactive and damage the parasite's essential proteins and cell membranes.
4
Parasite death: The damage leads to the death of the malaria parasite, reducing the parasite load in the blood.

💡 How to Take azeemal 15mg injection

Strength: Injection: 15 mg per ml. The total strength of the injection may vary based on the volume in the ampoule or vial.

1This medicine is given by a healthcare professional as an intramuscular injection.
2You will lie down or sit comfortably for the injection.
3The injection is usually given in the buttock.
4After the injection, you may be asked to stay for a short while to monitor for any reactions.
5Follow your doctor's instructions for follow-up oral antimalarial treatment.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 150 mg (which is 10 ml of the 15 mg/ml injection) given once daily for 3 days by intramuscular injection into the buttock. However, the exact dose and duration must be individualized by a qualified clinician based on the severity of malaria, the patient's weight, kidney and liver function, and other factors. This medicine is often followed by a full course of oral antimalarial tablets. Do not self-administer.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. This medicine may be used in children with severe malaria under strict medical supervision, but the dose must be calculated by a doctor based on the child's weight.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. The doctor will decide the dose based on kidney and liver function and overall health. Close monitoring is advised.
Renal ImpairmentDose adjustment may be needed in patients with kidney disease. Consult your doctor. Not established from the available information for specific dose adjustments.
Hepatic ImpairmentDose adjustment may be needed in patients with liver disease. Consult your doctor. Not established from the available information for specific dose adjustments.
Maximum Daily DoseThe maximum daily dose is usually 150 mg (10 ml of 15 mg/ml injection) for adults, but this must be confirmed by a qualified clinician. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Food
No specific food restrictions
This medicine is given by injection, so food does not affect it.

⏰ What to Do If You Miss a Dose

📌 You miss a scheduled injection
→ Contact your doctor or clinic as soon as possible to reschedule.
💡 Do not try to inject yourself. Do not double the dose.

⚠️ Side Effects of azeemal 15mg injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold compress if needed. It usually goes away in a day or two.
Fever (Common (5-10%))
Fever may be due to malaria itself. Take paracetamol if prescribed. Inform your doctor if it persists.
Headache (Common (5-10%))
Rest and stay hydrated. Consult your doctor if it is severe or persistent.
Dizziness (Common (5-10%))
Lie down and rest. Avoid driving or operating machinery until you feel better.
Nausea (Common (5-10%))
Eat small, light meals. Inform your doctor if vomiting occurs.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical help if you have rash, itching, swelling of face or throat, difficulty breathing, or a sudden drop in blood pressure.
Slow heart rate (bradycardia) (Rare (<0.1%))
Tell your doctor if you feel dizzy, faint, or have a very slow pulse.
Liver problems (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe stomach pain to your doctor immediately.
Kidney problems (Rare (<0.1%))
Inform your doctor if you notice decreased urine output or swelling in your legs.

⚠️ Rare Side Effects

Blood disorders
Report unusual bleeding, bruising, or fatigue to your doctor.
Seizures
Seek emergency medical attention if seizures occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Mefloquine Major
Rifampicin Major
Warfarin Moderate
Amiodarone Moderate
Paracetamol Minor

🚨 Major Interactions

  • Other antimalarials (e.g., mefloquine, lumefantrine)
  • Drugs that affect liver enzymes (e.g., rifampicin, carbamazepine)

⚡ Moderate Interactions

  • Warfarin
  • Drugs that can cause heart rhythm changes (e.g., amiodarone, sotalol)

🍷 Alcohol Interaction

Alcohol may worsen dizziness and liver stress. It is best to avoid alcohol while receiving this medicine and until you have fully recovered from malaria.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Allergy to Arteether or other artemisinin medicines","First trimester of pregnancy (unless life-threatening severe malaria)","Severe liver disease","Severe kidney disease"]

⚠️ Warnings & Precautions

["This medicine must only be given by a healthcare professional.","Do not use for preventing malaria.","Use with caution in patients with heart problems.","Use with caution in patients with liver or kidney disease.","Inform your doctor if you are pregnant or breastfeeding.","Complete the full course of oral antimalarial tablets after injection.","Avoid alcohol during treatment.","Do not drive or operate machinery if you feel dizzy."]

🤱 Lactation Safety

It is not known if Arteether passes into breast milk. Consult your doctor before breastfeeding while receiving this medicine. Your doctor will decide if it is safe based on your condition.

💊 Overdose Management

Overdose of this medicine is unlikely because it is given by a healthcare professional. If overdose is suspected, seek immediate medical attention. Treatment is supportive and may include monitoring of heart rate, blood pressure, and vital organs.

⏰ Missed Dose

This medicine is given by a healthcare professional, so a missed dose is unlikely. If you miss a scheduled injection, contact your doctor or clinic as soon as possible to reschedule. Do not try to inject yourself.

Additional Safety Advice

General Safety

This medicine must only be given by a qualified healthcare professional. Do not try to inject it yourself. Always tell your doctor if you are allergic to any medicine, especially antimalarials. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. This medicine is not recommended in the first trimester of pregnancy unless clearly needed. Tell your doctor about all other medicines you are taking, including herbal products. After the injection, you may feel dizzy or weak; rest for a while before driving or operating machinery. Complete the full course of oral antimalarial tablets prescribed after this injection to prevent the infection from coming back. Do not miss any follow-up appointments. Store this medicine as directed by the pharmacy, away from direct sunlight and out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more prone to side effects such as dizziness and heart rate changes. Close monitoring is advised. Dose adjustment may be needed based on kidney and liver function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, discuss with your doctor before receiving this medicine. It is not recommended in the first trimester unless absolutely necessary. Use effective contraception during treatment if you are of childbearing age and not planning pregnancy.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your surgeon and anesthesiologist about this medicine. It may affect heart rate and blood pressure. Your doctor will decide if it is safe to use.

🦷 Dental Procedures

Inform your dentist if you are receiving this medicine. It is generally safe for dental procedures, but your dentist may take precautions if you have heart rhythm issues.

💚 Lifestyle Tips for Better Results

🏃
Get plenty of rest while recovering from malaria.
🥗
Drink plenty of fluids to stay hydrated.
😴
Eat a healthy diet to regain strength.
💧
Avoid alcohol during treatment.
🧘
Use mosquito nets and repellents to prevent malaria.
🌞
Complete the full course of oral antimalarial tablets.

🏋️ Exercise Considerations

Avoid strenuous exercise until you have fully recovered from malaria. Start with light activities and gradually increase as you feel better. Consult your doctor before resuming intense exercise.

🥗 Diet Recommendations

Eat light, easily digestible meals.
Include fruits and vegetables rich in vitamins.
Stay well hydrated with water, soups, and juices.
Avoid oily and spicy foods if you have nausea.

💼 Impact on Daily Work & Life

You may feel weak and tired for a few days after treatment. Avoid driving or operating machinery if you feel dizzy. Take rest and return to work only when you feel fully recovered.

🛑 When to Stop This Medicine

Do not stop this medicine on your own. The course is usually for 3 days. If you experience severe side effects, your doctor may stop it. Always consult your doctor before stopping.

📅 Long-Term Use Effects

Long-term effects of this medicine are not well established because it is usually given for a short duration (3 days). However, repeated or prolonged use may increase the risk of liver or kidney problems. Monitoring may be needed if used for longer than recommended. Always follow your doctor's advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Artesunate injection

Another artemisinin derivative, often preferred for severe malaria.

Evidence: Well-established
Quinine injection

An older antimalarial used for severe malaria.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are due for a vaccine, inform your doctor. It is generally safe to receive vaccines during or after malaria treatment, but follow your doctor's advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

If you are traveling and need this medicine, carry it in its original packaging with a copy of your prescription. This medicine is given by a healthcare professional, so arrange for administration at a clinic or hospital. Store it at room temperature, away from direct sunlight. If traveling across time zones, follow the advice of your doctor regarding timing of doses. Check customs regulations for carrying injectable medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with severe malaria and vomiting
He was admitted with high fever, chills, and vomiting. He could not take oral medicines. He was given this injection once daily for 3 days. His fever came down within 2 days. After the injections, he was switched to oral antimalarial tablets and recovered fully.
💡 Lesson: This injection is life-saving for severe malaria when oral medicines cannot be taken.
👤 A 28-year-old pregnant woman in her second trimester with severe malaria
She was diagnosed with severe malaria and needed immediate treatment. After consulting with specialists, she was given this injection under close monitoring. She recovered well, and her pregnancy continued normally.
💡 Lesson: This medicine can be used in pregnancy if clearly needed, but only under strict medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within a few hours. Fever and other symptoms usually improve within 24 to 48 hours.

Q: Can I take this medicine at home?

A: No, this medicine must only be given by a trained healthcare professional in a clinic or hospital.

Q: Is this medicine safe in pregnancy?

A: It is not recommended in the first trimester unless absolutely necessary. In later pregnancy, it may be used if needed. Consult your doctor.

Q: What if I miss a dose?

A: Contact your doctor or clinic to reschedule. Do not try to inject yourself.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine at home?
  • How many days do I need this injection?
  • Is this medicine safe for children?
  • Can I take this medicine if I am pregnant?
  • What should I do if I miss a dose?
  • Can I drink alcohol while on this medicine?

🛑 Myths vs. Facts

  • Myth: Arteether injection can be used to prevent malaria.
    Fact: This medicine is only for treating severe malaria, not for prevention.
  • Myth: You can inject Arteether yourself at home.
    Fact: This medicine must only be given by a trained healthcare professional.
  • Myth: Arteether injection alone is enough to cure malaria.
    Fact: It is usually followed by a full course of oral antimalarial tablets to prevent recurrence.

🔄 Alternative Options

Generic Alternatives

  • Arteether injection

Brand Alternatives

  • Azeemal 15mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Arteether injection","class":"Artemisinin","route":"Intramuscular","use":"Severe malaria","note":"Given once daily for 3 days."},{"medicine":"Artesunate injection","class":"Artemisinin","route":"Intravenous or intramuscular","use":"Severe malaria","note":"First-line in many guidelines."},{"medicine":"Quinine injection","class":"Cinchona alkaloid","route":"Intravenous","use":"Severe malaria","note":"Older medicine, more side effects."}]

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