Axus S 100mg/10mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Severe skin rash with blistering
If experiencing severe symptoms, call emergency services immediately.
What is axus s 100mg/10mg tablet used for?
This medicine is a combination of Aceclofenac and Serratiopeptidase used to treat pain and inflammation in conditions like arthritis, post-surgical swelling, and injuries. It works by reducing pain-causing chemicals and breaking down inflammatory proteins. Take it with food to avoid stomach upset and follow your doctor's advice.
- Generic Name: Aceclofenac + Serratiopeptidase
- Manufacturer: Nexus Biotech
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 axus s 100mg/10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एसिटोक्लोफेनाक और सेरेशियोपेप्टिडेज़ का संयोजन है, जिसका उपयोग दर्द, सूजन और जलन को कम करने के लिए किया जाता है। यह गठिया, जोड़ों के दर्द, सर्जरी के बाद की सूजन, और चोट लगने पर होने वाले दर्द में प्रभावी है। यह दवा सूजन पैदा करने वाले रसायनों को रोककर और सूजन पैदा करने वाले प्रोटीन को तोड़कर काम करती है। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो। इसका उपयोग डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और त्वचा पर दाने शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत विषाक्तता और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकते हैं। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, पेशाब में कमी, आंखों या त्वचा का पीलापन, या चेहरे और गले में सूजन महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक या अवधि से अधिक न लें। पेट की जलन से बचने के लिए इसे भोजन या दूध के साथ लें। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ जाता है। बिना डॉक्टर की सलाह के अन्य दर्द निवारक दवाएं न लें। यदि आपको अल्सर, गुर्दे या यकृत की बीमारी, हृदय की समस्या या अस्थमा है, तो डॉक्टर को पहले बताएं। लंबे समय तक उपयोग के दौरान गुर्दे और यकृत की नियमित जांच करवाएं।
💊 axus s 100mg/10mg tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain, stiffness, and inflammation" class="semantic-link" title="Medicines for swelling">swelling in joints, improving mobility and quality of life.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint inflammation and pain, helping to maintain joint function.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Decreases back pain and stiffness, improving spinal flexibility.","evidence":"Well-established"},{"condition":"Post-operative inflammation","description":"Reduces swelling and pain after surgical procedures, aiding recovery.","evidence":"Well-established"},{"condition":"Post-traumatic inflammation","description":"Alleviates pain and swelling following injuries such as sprains and fractures.","evidence":"Well-established"},{"condition":"Dental pain and swelling","description":"Used to manage pain and inflammation after dental procedures or infections.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, though not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Inflammatory pain conditions such as osteoarthritis, rheumatoid arthritis, and post-operative inflammation.
Also treats: Ankylosing spondylitis, Dental pain, Post-traumatic inflammation, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Aceclofenac + Serratiopeptidase |
| Brand Name | Acimol-SP Tablet |
| Manufacturer | Nexus Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Proteolytic Enzyme |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac, an NSAID, inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, thereby reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Serratiopeptidase is a proteolytic enzyme that breaks down fibrin and other proteins involved in inflammation, thereby reducing swelling and promoting tissue repair. Together, they provide anti-inflammatory, analgesic, and anti-edema effects.
Mechanism Steps
💡 How to Take axus s 100mg/10mg tablet
Strength: Each tablet contains Aceclofenac 100 mg and Serratiopeptidase 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally twice daily, preferably with meals. However, the dose may vary depending on the condition being treated, its severity, and the patient's response. For acute conditions, it may be taken for a short duration, while for chronic conditions like arthritis, it may be continued for longer periods under medical supervision. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and renal impairment. Use with caution and at the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Avoid in severe renal impairment (creatinine clearance <30 mL/min). Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Avoid in severe hepatic impairment. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose of aceclofenac is 200 mg (two tablets of 100 mg). Do not exceed this dose without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of axus s 100mg/10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| ARBs | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Digoxin | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (e.g., ACE inhibitors, ARBs, diuretics)
- SSRIs
- Digoxin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulcers, and liver toxicity. It may also worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to aceclofenac, serratiopeptidase, or any component of the formulation","History of asthma, urticaria, or allergic reactions after taking aspirin or other NSAIDs","Active or history of recurrent peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe hepatic impairment","Severe renal impairment","Third trimester of pregnancy","Children under 18 years (safety and efficacy not established)","Coronary artery bypass graft (CABG) surgery peri-operative period"]
⚠️ Warnings & Precautions
["Take with food to minimize gastrointestinal irritation.","Avoid alcohol consumption.","Use with caution in elderly patients due to increased risk of side effects.","Monitor renal and hepatic function during long-term use.","May impair ability to drive or operate machinery due to dizziness.","Do not use for self-medication of minor pains without medical advice.","Consult doctor if symptoms persist beyond 7 days.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Serratiopeptidase may increase the risk of bleeding; use with caution in patients with bleeding disorders."]
🤱 Lactation Safety
Aceclofenac may pass into breast milk. Serratiopeptidase is likely safe as it is a protein and would be digested. However, due to lack of sufficient data, consult your doctor before use during breastfeeding.
💊 Overdose Management
Overdose may cause severe gastrointestinal pain, nausea, vomiting, bleeding, headache, dizziness, and renal impairment. Seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and renal function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. If you have a history of ulcers, kidney or liver disease, heart problems, or asthma, inform your doctor before taking this medicine. Regular monitoring of kidney and liver function may be needed during long-term use. Do not use this medicine for self-medication of minor aches and pains without medical advice.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly. Avoid concurrent use of other NSAIDs or anticoagulants.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before taking this medicine. NSAIDs like aceclofenac may affect ovulation and are generally avoided during pregnancy, especially in the third trimester. Discuss alternative pain management options with your doctor.
🏥 Post-Surgery Considerations
This medicine is often prescribed after surgery to manage pain and swelling. Take it as directed by your surgeon. Inform your surgeon if you have a history of ulcers or bleeding disorders. Monitor for signs of bleeding and report any unusual symptoms.
🦷 Dental Procedures
This medicine can be used for pain and swelling after dental procedures. Inform your dentist if you are taking this medicine before any dental work, as it may increase bleeding risk. Do not stop taking it without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. Low-impact exercises like swimming or walking are generally safe and beneficial for joint health.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take breaks and stay hydrated. Inform your employer if you need any accommodations.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience any serious side effects such as black stools, vomiting blood, severe abdominal pain, yellowing of eyes or skin, decreased urine output, or signs of an allergic reaction. Do not stop taking this medicine for chronic conditions without consulting your doctor, as abrupt discontinuation may worsen symptoms.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal ulcers, bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of renal and hepatic function, blood counts, and blood pressure is recommended. Use the lowest effective dose for the shortest duration. Consult your doctor for periodic reviews.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedApplying heat or cold packs can help reduce pain and swelling.
Evidence: Well-establishedMay provide pain relief for some individuals with chronic pain.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, continue taking it as prescribed, but adjust timing gradually to avoid missing doses. Check local customs regulations regarding prescription medicines. Always carry enough supply for your trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts relieving pain within 30-60 minutes after taking it. However, the full anti-inflammatory effect may take a few days of regular use.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset. Taking it on an empty stomach may increase the chance of gastrointestinal irritation.
A: Do not take other NSAIDs or painkillers without consulting your doctor, as it may increase the risk of side effects, especially gastrointestinal bleeding.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Do not stop taking this medicine without consulting your doctor, especially if you are being treated for a chronic condition. Your doctor will advise you on the appropriate duration.
🤔 Common Patient Concerns
🔄 Substitutes for axus s 100mg/10mg tablet
View AllAlternative brands with exact same active ingredient:
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cynac p 100mg/10mg tabletCyno Pharmaceuticals Ltd ₹32.34 34% CHEAPER
-
sdf 100mg/10mg tabletZoetic Formulations Pvt Ltd ₹49.22 0.4% COSTLIER
-
cycloplus 100mg/10mg tabletAbatis Holistic ₹51.56 5.2% COSTLIER
-
flamese sp 100mg/10mg tabletMeridian Medicare Ltd ₹53.44 9.1% COSTLIER
-
nutraflam 100mg/10mg tabletNutramedica Inc. ₹55.00 12.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of pain.
Fact: This medicine is specifically for inflammatory pain and should not be used for all types of pain without medical advice. - Myth: It is safe to take this medicine long-term without monitoring.
Fact: Long-term use requires regular monitoring of kidney and liver function due to potential side effects. - Myth: This medicine is safe to take during pregnancy.
Fact: NSAIDs like aceclofenac are generally avoided during pregnancy, especially in the third trimester, due to risks to the fetus.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 100 mg + Serratiopeptidase 10 mg tablet (various manufacturers)
Brand Alternatives
- Aceclo-SP
- Zerodol-SP
- Hifenac-SP
- Aceproxy-SP
- Acenac-SP