axpero 5 tablet
What is axpero 5 tablet used for?
Axpero 5 Tablet (Axitinib) is used to treat ANTI NEOPLASTICS. It contains Axitinib (5mg), which Inhibits receptor tyrosine kinases including VEGFR-1, VEGFR-2, VEGFR-3, PDGFR, a. Always consult your doctor before use. Take as prescribed.
- Generic Name: Axitinib
- Manufacturer: Intas Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ axpero 5 tablet Uses & Benefits
Advanced renal cell carcinoma after failure of prior systemic therapy.
Off-label uses: Other solid tumors (e.g., thyroid cancer, melanoma) with VEGFR expression.
๐ Drug Information
| Generic Name(s) | Axitinib |
| Brand Name | Axpero 5 Tablet |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Tyrosine kinase inhibitors |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits receptor tyrosine kinases including VEGFR-1, VEGFR-2, VEGFR-3, PDGFR, and c-KIT.
Mechanism Steps
๐ก How to Take axpero 5 tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of axpero 5 tablet
โ Common Side Effects
- Diarrhea
- Hypertension
- Fatigue
- Nausea
- Dysphonia
- Hand-foot skin reaction
๐จ Serious Side Effects
- Hemorrhage
- Gastrointestinal perforation
- Thrombotic events
- Hypertensive crisis
- Reversible posterior leukoencephalopathy syndrome
โ ๏ธ Rare Side Effects
- Pancreatitis
- Interstitial lung disease
- Nephrotic syndrome
- QT prolongation
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased axitinib exposure (AUC increased by 2-fold) |
| Rifampin | Major | Decreased axitinib exposure (AUC decreased by 79%) |
| Grapefruit juice | Minor | May increase axitinib levels |
๐จ Major Interactions
- Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole)
- Strong CYP3A4 inducers (e.g., rifampin, phenytoin)
โก Moderate Interactions
- Moderate CYP3A4 inhibitors (e.g., erythromycin, verapamil)
- Moderate CYP3A4 inducers (e.g., bosentan, efavirenz)
โน๏ธ Minor Interactions
- Grapefruit juice
- St. John's Wort
๐ฝ๏ธ Food Interactions
Avoid grapefruit juice; may increase plasma concentrations.
๐ท Alcohol Interaction
No specific interaction; caution due to potential hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to axitinib; pregnancy; severe hepatic impairment.
๐ Monitoring Parameters
Blood pressure, liver function, renal function, thyroid function, proteinuria, cardiac function.
๐คฑ Lactation Safety
Contraindicated; excreted in animal milk, potential harm to infant.
๐ Overdose Management
No specific antidote; symptomatic and supportive care.
โฐ Missed Dose
If missed, take as soon as remembered unless next dose is within 12 hours; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for axpero 5 tablet
View AllAlternative brands with exact same active ingredient (Axitinib (5mg)):
-
tykinax 5mg tabletDr Reddy's Laboratories Ltd โน1,406.02 31.7% CHEAPER
-
inlybest 5mg tabletAprazer Healthcare Pvt Ltd โน1,870.31 9.1% CHEAPER
-
bdaxit 5mg tabletBDR Pharmaceuticals Internationals Pvt โน2,070.00 0.6% COSTLIER
-
raxitinib 5mg tabletMedicamen Biotech Ltd โน2,160.00 5% COSTLIER
-
axishil 5mg tabletShilpa Medicare Ltd โน3,735.00 81.5% COSTLIER
-
axzyb tabletGlenmark Pharmaceuticals Ltd โน3,937.50 91.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Found this to be a helpful product. Good results.
Helpful and effective medicine as per my experience. Always consult a doctor.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.